Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Marko, Fonović"'
Autor:
Livija Tušar, Jure Loboda, Francis Impens, Piotr Sosnowski, Emmy Van Quickelberghe, Robert Vidmar, Hans Demol, Koen Sedeyn, Xavier Saelens, Matej Vizovišek, Marko Mihelič, Marko Fonović, Jaka Horvat, Gregor Kosec, Boris Turk, Kris Gevaert, Dušan Turk
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-15 (2023)
Abstract Addressing the elusive specificity of cysteine cathepsins, which in contrast to caspases and trypsin-like proteases lack strict specificity determining P1 pocket, calls for innovative approaches. Proteomic analysis of cell lysates with human
Externí odkaz:
https://doaj.org/article/ca692483d89a43aea2681a5be3fe722b
Publikováno v:
Viruses, Vol 16, Iss 2, p 232 (2024)
Bacteriophages, prokaryotic viruses, hold great potential in genetic engineering to open up new avenues for vaccine development. Our study aimed to establish engineered M13 bacteriophages expressing MAGE-A1 tumor peptides as a vaccine for melanoma tr
Externí odkaz:
https://doaj.org/article/3be89086974a4412a95e536e2e6a0496
Publikováno v:
Acta Chimica Slovenica, Vol 66, Iss 1, Pp 50-57 (2019)
Legumain or asparagine endopeptidase is a unique cysteine endopeptidase with a distinctive specificity for the hydrolysis of peptide bonds after asparagine and to a lesser extent after aspartate. It is ubiquitously expressed in various tissues and be
Externí odkaz:
https://doaj.org/article/4b4c36c181f3416a9823130898149664
Autor:
Katarina Hočevar, Matej Vizovišek, Alicia Wong, Joanna Kozieł, Marko Fonović, Barbara Potempa, Richard J. Lamont, Jan Potempa, Boris Turk
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
Porphyromonas gingivalis, the main etiologic agent of periodontitis, secretes cysteine proteases named gingipains. HRgpA and RgpB gingipains have Arg-specificity, while Kgp gingipain is Lys-specific. Together they can cleave an array of proteins and
Externí odkaz:
https://doaj.org/article/b5f84353b5654e30925e7e9b2cbb8b13
Autor:
Beáta Róka, Pál Tod, Tamás Kaucsár, Matej Vizovišek, Robert Vidmar, Boris Turk, Marko Fonović, Gábor Szénási, Péter Hamar
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 1, p 200 (2019)
(1) Background: Sepsis-induced acute kidney injury (AKI) is the most common form of acute kidney injury (AKI). We studied the temporal profile of the sepsis-induced renal proteome changes. (2) Methods: Male mice were injected intraperitoneally with b
Externí odkaz:
https://doaj.org/article/1bcc1f14f2714467826ee9fcc05f0b70
Autor:
Tina Zavašnik-Bergant, Robert Vidmar, Andreja Sekirnik, Marko Fonović, Jiří Salát, Lenka Grunclová, Petr Kopáček, Boris Turk
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 7 (2017)
To ensure successful feeding tick saliva contains a number of inhibitory proteins that interfere with the host immune response and help to create a permissive environment for pathogen transmission. Among the potential targets of the salivary cystatin
Externí odkaz:
https://doaj.org/article/1f4e448840424b1a869c507907d453e8
Publikováno v:
Cancers; Volume 14; Issue 18; Pages: 4524
Circular RNAs (circRNAs) have been shown to play an important role in the pathogenesis of hepatocellular carcinoma (HCC). By implementing available transcriptomic analyses of HCC patients, we identified an upregulated circRNA hsa_circ_0062682. Stable
Publikováno v:
Acta Chimica Slovenica, Vol 66, Iss 1, Pp 50-57 (2019)
Acta chimica slovenica
Acta chimica slovenica
Legumain or asparagine endopeptidase is a unique cysteine endopeptidase with a distinctive specificity for the hydrolysis of peptide bonds after asparagine and to a lesser extent after aspartate. It is ubiquitously expressed in various tissues and be
Autor:
Boris Turk, Marko Šoštar, Lucija Mijanović, Vedrana Filić, Matej Vizovišek, Marko Fonović, Jan Faix, Igor Weber, Alexander Junemann, Maja Marinović
Publikováno v:
Proceedings of the National Academy of Sciences
Macropinocytosis and phagocytosis are evolutionarily conserved forms of bulk endocytosis used by cells to ingest large volumes of fluid and solid particles, respectively. Both processes are regulated by Ras signaling, which is precisely controlled by
Publikováno v:
Matrix Biology. :141-159
Cysteine cathepsins have been for a long time considered to execute mainly nonspecific bulk proteolysis in the endolysosomal system. However, this view has been changing profoundly over the last decade as cathepsins were found in the cytoplasm, nucle