Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Markku Vaara"'
Autor:
Sara P. Cruz, Qin Zhang, Raman Devarajan, Christos Paia, Binjie Luo, Kai Zhang, Saara Koivusalo, Longguang Qin, Jihan Xia, Anne Ahtikoski, Markku Vaarala, Tomasz Wenta, Gong‐Hong Wei, Aki Manninen
Publikováno v:
Advanced Science, Vol 11, Iss 11, Pp n/a-n/a (2024)
Abstract The extracellular matrix (ECM) undergoes substantial changes during prostate cancer (PCa) progression, thereby regulating PCa growth and invasion. Herein, a meta‐analysis of multiple PCa cohorts is performed which revealed that downregulat
Externí odkaz:
https://doaj.org/article/8122d00339f94410a874a0dfe4629d49
Autor:
Juhani E. Syväoja, Minna Nyström, Helmut Pospiech, Bernhard Schlott, Sinikka Parkkinen, Jukka Kantelinen, Frank Grosse, Harri M. Itkonen, Markku Vaara
Publikováno v:
FEBS Letters. 590:4233-4241
High fidelity of genome duplication is ensured by cooperation of polymerase proofreading and mismatch repair (MMR) activities. Here, we show that human mismatch recognizing proteins MutS homolog 2 (MSH2) and MSH6 copurify and interact with replicativ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e74a488c6075b38d2019deece7af8eb
https://doi.org/10.1002/1873-3468.12475
https://doi.org/10.1002/1873-3468.12475
Autor:
Juhani E. Syväoja, Heinz-Peter Nasheuer, Helmut Pospiech, Harri Itkonen, Zhe Liu, Daniel Schaarschmidt, Tomi Hillukkala, Markku Vaara
Publikováno v:
Journal of Biological Chemistry. 287:33327-33338
DNA polymerases (Pol) alpha, delta, and is an element of replicate the bulk of chromosomal DNA in eukaryotic cells, Pol is an element of being the main leading strand and Pol delta the lagging strand DNA polymerase. By applying chromatin immunoprecip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7794b08c35601352993b4a1139cbdc9b
https://doi.org/10.1074/jbc.m112.357996
https://doi.org/10.1074/jbc.m112.357996
Autor:
Tamar Nethanel, Heinz-Peter Nasheuer, Maarit Jokela, Gabriel Kaufmann, Anna K. Rytkönen, Markku Vaara, Raija Sormunen, Tomi Hillukkala, Helmut Pospiech, Juhani E. Syväoja, Miiko Sokka
Publikováno v:
FEBS Journal. 273:5535-5549
DNA polymerase e co-operates with polymerases α and δ in the replicative DNA synthesis of eukaryotic cells. We describe here a specific physical interaction between DNA polymerase e and RNA polymerase II, evidenced by reciprocal immunoprecipitation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::75c162a69481558435fd5d734955c4ea
https://doi.org/10.1111/j.1742-4658.2006.05544.x
https://doi.org/10.1111/j.1742-4658.2006.05544.x
Autor:
Deqi Huang, Juhani E. Syväoja, Helmut Pospiech, Jussi T. Tuusa, Kaarina Reini, Inkeri Majuri, Thomas Westerling, Tomi P. Mäkelä, Minna Mäkiniemi, Markku Vaara, Tomi Hillukkala
Publikováno v:
Journal of Biological Chemistry. 276:30399-30406
Topoisomerase IIbeta-binding protein (TopBP1), a human protein with eight BRCT domains, is similar to Saccharomyces cerevisiae Dpb11 and Schizosaccharomyces pombe Cut5 checkpoint proteins and closely related to Drosophila Mus101. We show that human T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::428f38a2ad247c60754efa8b5b36c7ba
https://doi.org/10.1074/jbc.m102245200
https://doi.org/10.1074/jbc.m102245200
Autor:
Markku Vaara, Seiki Nakao, Sufang Zhang, Shinya Oda, Peter Karran, Marietta Y.W.T. Lee, Toshiki Tsurimoto, Juhani E. Syväoja
Publikováno v:
Biochimie. 95(2)
In vitro assay of mammalian DNA replication has been variously approached. Using gapped circular duplex substrates containing a 500-base single-stranded DNA region, we have constructed a mammalian cell-free system in which physiological DNA replicati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a0a0cd16579441d51bfee05adfaf5e4
https://pubmed.ncbi.nlm.nih.gov/23063694
https://pubmed.ncbi.nlm.nih.gov/23063694
Autor:
Elisa Mäkäräinen-Uhlbäck, Jaana Vironen, Markku Vaarala, Pia Nordström, Anu Välikoski, Jyrki Kössi, Ville Falenius, Aristotelis Kechagias, Anne Mattila, Pasi Ohtonen, Tom Scheinin, Tero Rautio
Publikováno v:
BMC Surgery, Vol 21, Iss 1, Pp 1-5 (2021)
Abstract Background Previous research on parastomal hernia repair following ileal conduit urinary diversion is limited. This nationwide cohort study aims to present the results of keyhole and Sugarbaker techniques in parastomal hernia repair in the s
Externí odkaz:
https://doaj.org/article/19504a6bdd764b6e8dafbca502d03a25
Autor:
Anna K, Rytkönen, Tomi, Hillukkala, Markku, Vaara, Miiko, Sokka, Maarit, Jokela, Raija, Sormunen, Heinz-Peter, Nasheuer, Tamar, Nethanel, Gabriel, Kaufmann, Helmut, Pospiech, Juhani E, Syväoja
Publikováno v:
The FEBS journal. 273(24)
DNA polymerase epsilon co-operates with polymerases alpha and delta in the replicative DNA synthesis of eukaryotic cells. We describe here a specific physical interaction between DNA polymerase epsilon and RNA polymerase II, evidenced by reciprocal i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8621c79a26a593edc89be1874be550a7
https://pubmed.ncbi.nlm.nih.gov/17212775
https://pubmed.ncbi.nlm.nih.gov/17212775
Autor:
Markku Vaara, Gabriel Kaufmann, Amal Rahmeh, Anna K. Rytkönen, Helmut Pospiech, Marietta Y.W.T. Lee, Juhani E. Syväoja, Esa Läärä, Heinz-Peter Nasheuer, Raija Sormunen, Tamar Nethanel
Publikováno v:
The FEBS journal. 273(13)
The contributions of human DNA polymerases (pols) alpha, delta and epsilon during S-phase progression were studied in order to elaborate how these enzymes co-ordinate their functions during nuclear DNA replication. Pol delta was three to four times m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92b009ae142042d4db506ad241aaa38c
https://pubmed.ncbi.nlm.nih.gov/16762037
https://pubmed.ncbi.nlm.nih.gov/16762037