Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Markku Vänttinen"'
Autor:
Patricia Iozzo, Kirsti Hällsten, Juhani Knuuti, Ronald Borra, Jukka Kemppainen, Teemu Takala, Jussi Pihlajamäki, Markku Laakso, Pirjo Nuutila, Miikka-Juhani Honka, Kirsi A. Virtanen, Markku Vänttinen, Antti Viljanen, Riikka Lautamäki
Publikováno v:
METABOLISM-CLINICAL AND EXPERIMENTAL, 58(4), 541-546. W B SAUNDERS CO-ELSEVIER INC
The Ala12 allele of the peroxisome proliferator-activated receptor gamma gene (PPARG2) has been associated with reduced risk of type 2 diabetes mellitus (T2DM) and increased whole-body and skeletal muscle insulin sensitivity in nondiabetic subjects.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f794624ef17b115e70b54d0d871ff6c
https://doi.org/10.1016/j.metabol.2008.11.015
https://doi.org/10.1016/j.metabol.2008.11.015
Autor:
Ann Hammarstedt, Per-Anders Jansson, Maria Adelaide Marini, Andreas Fritsche, Alena Stančáková, Jone Zilinskaite, Giorgio Sesti, Hans-Ulrich Häring, Norbert Stefan, Markku Laakso, Harald Staiger, Oluf Pedersen, Ulf Smith, Torben Hansen, Markku Vänttinen
Publikováno v:
Diabetes. 57:514-517
OBJECTIVE—In recent genome-wide association studies, two single nucleotide polymorphisms (SNPs) near the HHEX locus were shown to be more frequent in type 2 diabetic patients than in control subjects. Based on HHEX's function during embryonic devel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29d06fe62602919639621ff32facf2c2
https://doi.org/10.2337/db07-1254
https://doi.org/10.2337/db07-1254
Autor:
Markku Vänttinen, Jarno Rutanen, Markku Laakso, Johanna Kuusisto, Sakari Kainulainen, Jussi Pihlajamäki, Urpu Salmenniemi, Eija Ruotsalainen, Teemu Kuulasmaa
Publikováno v:
Obesity. 15:2902-2907
Melanin concentrating hormone receptor-1 (MCHR1) is a centrally and peripherally expressed receptor that regulates energy expenditure and appetite. Single nucleotide polymorphisms (SNPs) of the MCHR1 gene have been previously associated with obesity,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::028a34dce93958d95637ef7a06bca1e6
https://doi.org/10.1038/oby.2007.345
https://doi.org/10.1038/oby.2007.345
Autor:
Urpu Salmenniemi, Teemu Kuulasmaa, Jarno Rutanen, Markku Laakso, Sakari Kainulainen, Eija Ruotsalainen, Jussi Pihlajamäki, Markku Vänttinen
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 92:1112-1117
The melanocortin-3 receptor (MC3R) is a part of the melanocortin system that regulates appetite and energy metabolism. The Thr/Thr 6 and Val/Val81 [corrected] polymorphisms of the MC3R gene have been previously associated with high insulin levels and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f94d283f7862abbed687d4b3c273b5c
https://doi.org/10.1210/jc.2006-1201
https://doi.org/10.1210/jc.2006-1201
Autor:
Antti Viljanen, Teemu Takala, Pirjo Nuutila, Markku Vänttinen, Kirsti Hällsten, Jukka Kemppainen, Riikka Lautamäki, Pauliina Peltoniemi, Juhani Knuuti, Jussi Pihlajamäki, Kirsi A. Virtanen, Markku Laakso
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 90:4249-4254
The Pro(12)Ala polymorphism of the peroxisome proliferator-activated receptor-gamma2 gene is associated with insulin sensitivity. Obesity is a major risk factor for insulin resistance, but the association of the Pro(12)Ala polymorphism with body weig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26dec282aacd7a38bded0911c70bb8ec
https://doi.org/10.1210/jc.2005-0101
https://doi.org/10.1210/jc.2005-0101
Autor:
Harald, Staiger, Alena, Stancáková, Jone, Zilinskaite, Markku, Vänttinen, Torben, Hansen, Maria Adelaide, Marini, Ann, Hammarstedt, Per-Anders, Jansson, Giorgio, Sesti, Ulf, Smith, Oluf, Pedersen, Markku, Laakso, Norbert, Stefan, Andreas, Fritsche, Hans-Ulrich, Häring
In recent genome-wide association studies, two single nucleotide polymorphisms (SNPs) near the HHEX locus were shown to be more frequent in type 2 diabetic patients than in control subjects. Based on HHEX's function during embryonic development of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::f3250082c44bb40094b85ee39d67a520
http://hdl.handle.net/2108/43750
http://hdl.handle.net/2108/43750
Autor:
J. Zilinskaite, Fredrik Pellmé, Torben Hansen, T. Welløv Boesgaard, Markku Vänttinen, Norbert Stefan, Markku Laakso, Marta Letizia Hribal, Giorgio Sesti, Andreas Fritsche, Alena Stančáková, Oluf Pedersen, Ulf Smith, Per-Anders Jansson, J. J. Holst, HU Häring, Teemu Kuulasmaa
AIMS/HYPOTHESIS: We examined the phenotype of individuals with impaired fasting glucose (IFG) and/or impaired glucose tolerance (IGT) with regard to insulin release and insulin resistance. METHODS: Non-diabetic offspring (n=874; mean age 40+/-10.4 ye
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe038b11468af9bee0b3d78945410d7b
http://hdl.handle.net/11588/705583
http://hdl.handle.net/11588/705583
Autor:
Teemu Kuulasmaa, Jon Lindstrom, Jianjun Wang, Markku Vänttinen, J. Tuomilehto, M. I. J. Uusitupa, Johanna Kuusisto, Markku Laakso
Publikováno v:
Diabetologia. 50(6)
We investigated the association of variants of the transcription factor 7-like 2 (TCF7L2) gene with: (1) incident diabetes in the Finnish Diabetes Prevention Study (DPS, Study I); (2) type 2 diabetes and impaired glucose regulation (i.e. IGT or IFG)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bc0b190065d4a5ed70b8be452719942
https://pubmed.ncbi.nlm.nih.gov/17437080
https://pubmed.ncbi.nlm.nih.gov/17437080
Autor:
Jussi Pihlajamäki, Nancy J. Cox, I. Vauhkonen, Markku Vänttinen, Maggie C.Y. Ng, Johanna Kuusisto, Markku Laakso, Eija Ruotsalainen, Urpu Salmenniemi, Graeme I. Bell, Sakari Kainulainen
Publikováno v:
Diabetologia. 49(7)
The mechanisms by which the calpain-10 gene (CAPN10) affects the risk of type 2 diabetes are unclear. Therefore, we investigated the effects of four polymorphisms in CAPN10 (single nucleotide polymorphism [SNP]-43, SNP-44, Insertion/Deletion [Indel]-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1de24adfa398bb5c7203a58a9184c6f9
https://pubmed.ncbi.nlm.nih.gov/16752174
https://pubmed.ncbi.nlm.nih.gov/16752174
Autor:
Juhani Knuuti, Antti Viljanen, Pauliina Peltoniemi, Jussi Pihlajamäki, Markku Vänttinen, Kirsti Hällsten, Kirsi A. Virtanen, Riikka Lautamäki, Teemu Takala, Teemu Kuulasmaa, Markku Laakso, Pirjo Nuutila
Publikováno v:
Diabetes. 54(12)
The peroxisome proliferator–activated receptors (PPARs) belong to a superfamily of nuclear receptors. It includes PPAR-δ, a key regulator of fatty acid oxidation and energy uncoupling, universally expressed in different tissues. The PPAR-δ gene (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::963471d9fe272caaf758b87067cf0d89
https://pubmed.ncbi.nlm.nih.gov/16306381
https://pubmed.ncbi.nlm.nih.gov/16306381