Zobrazeno 1 - 10
of 344
pro vyhledávání: '"Markku Seppälä"'
Autor:
Jannica S. Selenius, Patricia P. Silveira, Mikaela von Bonsdorff, Jari Lahti, Hannu Koistinen, Riitta Koistinen, Markku Seppälä, Johan G. Eriksson, Niko S. Wasenius
Publikováno v:
Diabetes & Metabolism Journal, Vol 48, Iss 5, Pp 960-970 (2024)
Background To investigate associations between variations in the co-expression-based brain insulin receptor polygenic score and cardiometabolic risk factors and diabetes mellitus. Methods This cross-sectional study included 1,573 participants from th
Externí odkaz:
https://doaj.org/article/84938c1dd65e4ea9907ca5c26c24d518
Autor:
Madhavi, Vijayan, Cheuk-Lun, Lee, Vera H H, Wong, Xia, Wang, Kungfeng, Bai, Jian, Wu, Hannu, Koistinen, Markku, Seppälä, Kai-Fai, Lee, William S B, Yeung, Ernest H Y, Ng, Philip C N, Chiu
Publikováno v:
Journal of cell science. 133(14)
Decidual macrophages constitute 20-30% of the total leukocytes in the uterus of pregnant women, regulating the maternal immune tolerance and placenta development. Abnormal number or activities of decidual macrophages (dMs) are associated with fetal l
Autor:
Jian Wu, Markku Seppälä, Kungfeng Bai, Philip C.N. Chiu, Kai-Fai Lee, Ernest Hung Yu Ng, William S.B. Yeung, Hannu Koistinen, Madhavi Vijayan, Cheuk-Lun Lee, Vera H.H. Wong, Xia Wang
Publikováno v:
Journal of Cell Science.
Decidual macrophages constitute 20-30% of the total leukocytes in the uterus of pregnant women, regulating the maternal immune tolerance and placenta development. Abnormal number or activities of decidual macrophages (dMs) are associated with fetal l
Autor:
Ernest Hung Yu Ng, Xia Wang, Madhavi Vijayan, Kevin K.W. Lam, Raymond H.W. Li, Cheuk-Lun Lee, Markku Seppälä, Philip C.N. Chiu, Hannu Koistinen, William S.B. Yeung
Publikováno v:
Human reproduction (Oxford, England). 34(4)
Study question Does glycodelin-A (GdA) induce conversion of human peripheral blood CD16-CD56bright natural killer (NK) cells to decidual NK (dNK) cells to facilitate placentation? Summary answer GdA binds to blood CD16-CD56bright NK cells via its sia
Publikováno v:
American Journal of Reproductive Immunology. 69:42-170
Autor:
Maciej Kurpisz, Kevin K.W. Lam, Hannu Koistinen, Nelson Fernandez, Markku Seppälä, Ronald T.K. Pang, Cheuk-Lun Lee, William S.B. Yeung, Philip C.N. Chiu
Publikováno v:
Journal of Reproductive Immunology. 90:29-34
Glycodelin-A (GdA) is a glycoprotein secreted from the endometrial glands and decidual glandular epithelium. Given its abundance and ubiquitous distribution in the first trimester uterus, GdA may be involved in early placental development via its mod
Autor:
Riitta Koistinen, Kai-Fai Lee, Philip C.N. Chiu, Ivan K. Chu, Markku Seppälä, Cheuk-Lun Lee, William S.B. Yeung, Maria Panico, Howard R. Morris, Hannu Koistinen, Anne Dell, Poh-Choo Pang, Bérangère Tissot
Publikováno v:
Diabetes. 60:909-917
OBJECTIVE Gestational diabetes mellitus (GDM) is a common metabolic disorder of pregnancy. Patients with GDM are at risk for high fetal mortality and gestational complications associated with reduced immune tolerance and abnormal carbohydrate metabol
Autor:
Markku Seppälä, S. O. Siu, Hannu Koistinen, Riitta Koistinen, Ivan K. Chu, Kai-Fai Lee, Cheuk-Lun Lee, Kevin K.W. Lam, Philip C.N. Chiu, William S.B. Yeung
Publikováno v:
Human Reproduction. 26:517-526
background: The maternal –fetal interface has a unique immunological response towards the implanting placenta. It is generally accepted that a T-helper type-2 (Th-2) cytokine prevailing environment is important in pregnancy. The proportion of Th-2
Autor:
Fernando Larrea, Marta Durand, Riitta Koistinen, Markku Seppälä, José Luis Rodríguez, Elena Zambrano, Mayel Chirinos
Publikováno v:
Contraception. 82:526-533
Background The study was conducted to assess the effects of levonorgestrel (LNG) on hormonal behavior and on the secretory pattern of intrauterine glycodelin at the midcycle of ovulatory women. Study Design Thirty healthy sterilized women with normal
Autor:
Laura Hautala, Markku Seppälä, Wsb Yeung, Philip C.N. Chiu, Riitta Koistinen, Hannu Koistinen
Publikováno v:
European Journal of Endocrinology. 160:121-133
Glycodelin is an endocrine-regulated glycoprotein that has significant effects on immune cells, apoptosis, reproduction, cell adhesion, differentiation and cancer. In reproduction, glycodelin contributes to capacitation and immunoprotection of sperma