Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Markku Peräaho"'
Autor:
Valeriia Dotsenko, Mikko Oittinen, Juha Taavela, Alina Popp, Markku Peräaho, Synnöve Staff, Jani Sarin, Francisco Leon, Jorma Isola, Markku Mäki, Keijo Viiri
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 1, Pp 13-32 (2021)
Background & Aims: Gluten challenge studies are instrumental in understanding the pathophysiology of celiac disease. Our aims in this study were to reveal early gluten-induced transcriptomic changes in duodenal biopsies and to find tools for clinics.
Externí odkaz:
https://doaj.org/article/903f1c5952eb4cb0ba7ff22dc96ad2f9
Autor:
Juha Taavela, Keijo Viiri, Alina Popp, Mikko Oittinen, Valeriia Dotsenko, Markku Peräaho, Synnöve Staff, Jani Sarin, Francisco Leon, Markku Mäki, Jorma Isola
Publikováno v:
BMC Gastroenterology, Vol 19, Iss 1, Pp 1-10 (2019)
Abstract Background There is an unmet need for novel treatments, such as drugs or vaccines, adjunctive to or replacing a burdensome life-long gluten-free diet for coeliac disease. The gold standard for successful treatment is a healed small intestina
Externí odkaz:
https://doaj.org/article/8c0ba4ac103841a88a91d20b653f154e
Autor:
Markku Peräaho, Francisco León, Markku Mäki, Valeriia Dotsenko, Alina Popp, Jorma Isola, Keijo Viiri, Jani Sarin, Synnöve Staff, Mikko Oittinen, Juha Taavela
Background & AimsGluten challenge studies are instrumental in understanding the pathophysiology of celiac disease. Our aims in this study were to reveal early gluten-induced transcriptomic changes in duodenal biopsies and to find tools for clinics.Me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::63694888ec0b5149d413d9cc5df497c0
https://doi.org/10.1101/2020.04.17.20067942
https://doi.org/10.1101/2020.04.17.20067942
Autor:
Ilkka Vihriälä, Jari Punkkinen, Tero Ylisaukko-oja, Taina Sipponen, Eija Hirsi, Christian Nielsen, Jyrki Tillonen, Markku Pajala, Jouni Silvennoinen, Ville Liukkonen, Mikko Kellokumpu, Jari Jokelainen, Henna Rautiainen, Veikko Moilanen, Hans Henricson, Hannu Sulonen, Mirva Esterinen, Timo Blomster, Kari Toljamo, Klaus Tamminen, Pauliina Molander, Airi Jussila, Jaakko Aaltonen, Juha Kuisma, Petri Mäkelä, Kalle Hakala, Margus Lääne, Kimmo Salminen, Sauli Herrala, Ulla-Maija Suhonen, Mika Puhto, Markku Peräaho, Heikki Nuutinen
Publikováno v:
Scandinavian Journal of Gastroenterology. 53:158-167
Objectives: The efficacy and tolerability of vedolizumab in the treatment of inflammatory bowel diseases (IBD) has been demonstrated in an extensive GEMINI clinical trial programme. Clinical trials represent highly selected patient populations and, t
Autor:
Klaus Tamminen, Mikko Kellokumpu, Tero Ylisaukko-oja, Sauli Herrala, Markku Peräaho, Taina Sipponen, Henna Rautiainen, Petri Mäkelä, Jari Jokelainen, Ulla-Maija Suhonen, Heikki Nuutinen, Markku Pajala, Mirva Esterinen, Margus Lääne, Mika Puhto, Christian Nielsen, Jyrki Tillonen, Veikko Moilanen, Juha Kuisma, Ville Liukkonen, Kalle Hakala, Pauliina Molander, Hannu Sulonen, Saku Torvinen, Jaakko Aaltonen, Jouni Silvennoinen, Hans Henricson, Ilkka Vihriälä, Eija Hirsi, Kari Toljamo, Airi Jussila, Jari Punkkinen, Timo Blomster, Kimmo Salminen
Publikováno v:
Biologicals : journal of the International Association of Biological Standardization. 58
Limited data is available on vedolizumab combination therapies in real-world clinical practice. Here, we evaluated the concomitant corticosteroid, immunosuppressive, and 5-aminosalicylic acid utilization of inflammatory bowel disease (IBD) patients t
Autor:
Jukka Partanen, Markku Peräaho, Katri Kaukinen, Katri Lindfors, Pekka Collin, N. Woolley, Outi Koskinen, Markku Mäki, Kaija Laurila
Publikováno v:
Digestive and Liver Disease. 42:692-697
Background and aims The diagnosis of coeliac disease is problematic in individuals not responding to a gluten-free diet. Small-bowel villous atrophy occurs in other enteropathies and non-responsive patients are often seronegative. We investigated whe
Autor:
Eeva Pehkonen, Jahangir Khan, Pekka Pikkarainen, Tuula Mäkelä, Pekka Collin, Anna-Liisa Karvonen, Markku Peräaho
Publikováno v:
Scandinavian Journal of Gastroenterology. 44:970-974
To assess the aetiology, prognosis and prevalence of spontaneous bacterial peritonitis (SBP) in patients hospitalized for ascites. The validity of an elevated (11 g/l) serum-ascites albumin gradient (SAAG) in the diagnostic work-up was evaluated. Mor
Autor:
Harri Sievänen, Pekka Collin, N. Woolley, Markku Peräaho, Jukka Partanen, Pekka Pikkarainen, Katri Lindfors, Katri Kaukinen, Anna-Liisa Karvonen, Markku Mäki, T. Laasanen
Publikováno v:
Alimentary Pharmacology & Therapeutics. 25:1237-1245
SUMMARY Background Refractory sprue with malabsorption carries a risk of lymphoma. Aim To examine whether a good clinical but poor histological response during a strict gluten-free diet predicts a poor outcome. Methods The study involved all coeliac
Autor:
Markku Peräaho, Harri Sievänen, S Lohiniemi, K. Paasikivi, Markku Mäki, Pekka Collin, Katri Kaukinen
Publikováno v:
Alimentary Pharmacology & Therapeutics. 17:587-594
Summary Background : The safety of wheat-starch-based gluten-free products in the treatment of coeliac disease is debatable. Prospective studies are lacking. Aim : To compare the clinical, histological and serological response to a wheat-starch-based
Publikováno v:
Annals of Medicine. 33:445-449
Neurological symptoms of unknown origin are common in coeliac disease (CD). Evidence suggests that CD may also contribute to the development of idiopathic late-onset ataxia.To evaluate the frequency of CD in patients with cerebellar ataxia of unknown