Measurement of brown adipose tissue mass using a novel dual-echo magnetic resonance imaging approach: A validation study

Autor: Jukka Laine, Virva Lepomäki, Jarna C. Hannukainen, Milja Holstila, Pirjo Nuutila, Jani Saunavaara, Tove J. Grönroos, Irina Lisinen, Markku Komu, Ronald Borra, Kirsi A. Virtanen, Riitta Parkkola

Publikováno v: METABOLISM-CLINICAL AND EXPERIMENTAL, 62(8), 1189-1198. W B SAUNDERS CO-ELSEVIER INC

Objective. The aim of this study was to evaluate and validate magnetic resonance imaging (MRI) for the visualization and quantification of brown adipose tissue (BAT) in vivo in a rat model. We hypothesized that, based on differences in tissue water a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74e16e64157fae6911d346a21f136584
https://doi.org/10.1016/j.metabol.2013.03.002

Effect of antenatal growth on brain white matter maturation in preterm infants at term using tract-based spatial statistics

Autor: Jaakko Matomäki, Leena Haataja, Markku Komu, Riitta Parkkola, Liisa Lehtonen, Helena Lapinleimu, Virva Lepomäki

Publikováno v: Pediatric Radiology. 43:80-85

White matter maturation of infants can be studied using diffusion tensor imaging (DTI). DTI of the white matter of the infant brain provides the best available clinical measures of brain tissue organisation and integrity. The purpose of this study wa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fee8f05bb5d27874f99ef8dc8b37d16e
https://doi.org/10.1007/s00247-012-2509-9

Liver and pancreatic fat content and metabolism in healthy monozygotic twins with discordant physical activity

Autor: Pirjo Nuutila, Markku Komu, Terho Lehtimäki, Virva Lepomaki, Kaisa M. Linderborg, Urho M. Kujala, Risto Huupponen, Ronald Borra, Jarna C. Hannukainen, Jan Kiss, Markku Ahotupa, Heikki Kallio, Jaakko Kaprio, Riitta Parkkola, Kari K. Kalliokoski, Patricia Iozzo, Olli J. Heinonen

Publikováno v: Journal of Hepatology, 54(3), 545-552. ELSEVIER SCIENCE BV

Background & Aims: Ectopic fat in muscle and liver is linked to obesity and type 2 diabetes. Recently, pancreatic lipid accumulation has also been associated with beta-cell dysfunction and reduced insulin production, leading to the development of typ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59839b9d2fee220f2b71b521dc0fbe88
http://juuli.fi/Record/0253082911

Quantitative liver iron measurement by magnetic resonance imaging: in vitro and in vivo assessment of the liver to muscle signal intensity and the R2* methods

Autor: Johanna Virtanen, Markku Komu, Riitta Parkkola

Publikováno v: Magnetic Resonance Imaging. 26:1175-1182

Purpose To evaluate the liver-to-muscle signal intensity and R2* methods to gain a transferable, clinical application for liver iron measurement. Materials and Methods Sixteen liver phantoms and 33 human subjects were examined using three 1.5-T MRI s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb6458bd44bd493b0b6012c80fd61a12
https://doi.org/10.1016/j.mri.2008.01.028

Liver steatosis coexists with myocardial insulin resistance and coronary dysfunction in patients with type 2 diabetes

Autor: K.E. Juhani Airaksinen, Ronald Borra, Markku Komu, Pirjo Nuutila, Terho Lehtimäki, Riikka Lautamäki, Sirpa Jalkanen, Juhani Knuuti, Riitta Parkkola, Patricia Iozzo, Marko Salmi

Publikováno v: American Journal of Physiology-Endocrinology and Metabolism, 291(2), E282-E290. AMER PHYSIOLOGICAL SOC
Diabetes, 55. AMER DIABETES ASSOC

Nonalcoholic fatty liver (NAFL) is a common comorbidity in patients with type 2 diabetes and links to the risk of coronary syndromes. The aim was to determine the manifestations of metabolic syndrome in different organs in patients with liver steatos

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33c82b2a5aabdf2f3eedc1a0a2d8a872
https://doi.org/10.1152/ajpendo.00604.2005