Zobrazeno 1 - 10
of 239
pro vyhledávání: '"Markku A. Savolainen"'
Autor:
Noora Oikarinen, Terhi Jokelainen, Laura Heikkilä, Marjukka Nurkkala, Janne Hukkanen, Tuire Salonurmi, Markku J. Savolainen, Anna-Maria Teeriniemi
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Success in long-term weight management depends partly on psychological and behavioral aspects. Understanding the links between psychological factors and eating behavior tendencies is needed to develop more effective weight management methods
Externí odkaz:
https://doaj.org/article/91f9ce8784d34faa828a4611ae220b9e
Autor:
Markku J. Savolainen, Antti Karlsson, Samppa Rohkimainen, Iiro Toppila, Mariann I. Lassenius, Carlos Vaca Falconi, Kristiina Uusi-Rauva, Kaisa Elomaa
Publikováno v:
Molecular Genetics and Metabolism Reports, Vol 27, Iss , Pp 100725- (2021)
Background: Gaucher disease (GD) is a rare inherited multiorgan disorder, yet a diagnosis can be significantly delayed due to a broad spectrum of symptoms and lack of disease awareness. Recently, the prototype of a GD point-scoring system (PSS) was e
Externí odkaz:
https://doaj.org/article/38f284b8027447c3a34e8bc0e1e81f11
Publikováno v:
Lipids in Health and Disease, Vol 17, Iss 1, Pp 1-9 (2018)
Abstract Background Krill powder is rich in bioactive ingredients such as eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), phospholipids, protein and astaxanthin. Containing dominantly EPA, it is considered to be effective in lowering lipids,
Externí odkaz:
https://doaj.org/article/77c86312b19941adb8258b4a8a72326b
Autor:
Tuire Salonurmi, Heba Nabil, Justiina Ronkainen, Tuulia Hyötyläinen, Heidi Hautajärvi, Markku J. Savolainen, Ari Tolonen, Matej Orešič, Päivi Känsäkoski, Jaana Rysä, Jukka Hakkola, Janne Hukkanen
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Activation of pregnane X receptor (PXR) elevates circulating 4β-hydroxycholesterol (4βHC), an agonist of liver X receptor (LXR). PXR may also regulate 25-hydroxycholesterol and 27-hydroxycholesterol. Our aim was to elucidate the roles of PXR and ox
Externí odkaz:
https://doaj.org/article/fb0247ae26fc400a98ce2a9c876ed0e1
Autor:
Johannes Kettunen, Ayşe Demirkan, Peter Würtz, Harmen H.M. Draisma, Toomas Haller, Rajesh Rawal, Anika Vaarhorst, Antti J. Kangas, Leo-Pekka Lyytikäinen, Matti Pirinen, René Pool, Antti-Pekka Sarin, Pasi Soininen, Taru Tukiainen, Qin Wang, Mika Tiainen, Tuulia Tynkkynen, Najaf Amin, Tanja Zeller, Marian Beekman, Joris Deelen, Ko Willems van Dijk, Tõnu Esko, Jouke-Jan Hottenga, Elisabeth M van Leeuwen, Terho Lehtimäki, Evelin Mihailov, Richard J. Rose, Anton J.M. de Craen, Christian Gieger, Mika Kähönen, Markus Perola, Stefan Blankenberg, Markku J. Savolainen, Aswin Verhoeven, Jorma Viikari, Gonneke Willemsen, Dorret I. Boomsma, Cornelia M. van Duijn, Johan Eriksson, Antti Jula, Marjo-Riitta Järvelin, Jaakko Kaprio, Andres Metspalu, Olli Raitakari, Veikko Salomaa, P. Eline Slagboom, Melanie Waldenberger, Samuli Ripatti, Mika Ala-Korpela
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-9 (2016)
Circulating metabolites reflect human health and disease. Here, Kettunen et al. perform a genome-wide association study on 123 circulating metabolic traits and identify novel genetic loci influencing systemic metabolism. They also link new molecular
Externí odkaz:
https://doaj.org/article/efa9e82fc86e4339bfe2f9945de63686
Autor:
Gözde Gürdeniz, Matti Uusitupa, Kjeld Hermansen, Markku J. Savolainen, Ursula Schwab, Marjukka Kolehmainen, Lea Brader, Lieselotte Cloetens, Karl-Heinz Herzig, Janne Hukkanen, Fredrik Rosqvist, Stine Marie Ulven, Ingibjörg Gunnarsdóttir, Inga Thorsdottir, Matej Oresic, Kaisa S. Poutanen, Ulf Risérus, Björn Åkesson, Lars Ove Dragsted
Publikováno v:
Gürdeniz, G, Uusitupa, M, Hermansen, K, Savolainen, M J, Schwab, U, Kolehmainen, M, Brader, L, Cloetens, L, Herzig, K H, Hukkanen, J, Rosqvist, F, Ulven, S M, Gunnarsdóttir, I, Thorsdottir, I, Orešič, M, Poutanen, K S, Risérus, U, Åkesson, B & Dragsted, L O 2022, ' Analysis of the SYSDIET Healthy Nordic Diet randomized trial based on metabolic profiling reveal beneficial effects on glucose metabolism and blood lipids ', Clinical Nutrition, vol. 41, no. 2, pp. 441-451 . https://doi.org/10.1016/j.clnu.2021.12.031
Gürdeniz, G, Uusitupa, M, Hermansen, K, Savolainen, MJ, Schwab, U, Kolehmainen, M, Brader, L J, Cloetens, L, Herzig, K-H, Hukkanen, J, Rosqvist, F, Ulven, SM, Gunnarsdóttir, I, Thorsdottir, I, Oresic, M, Poutanen, KS, Risérus, U, Åkesson, B & Dragsted, L O 2022, ' Analysis of the SYSDIET Healthy Nordic Diet randomized trial based on metabolic profiling reveal beneficial effects on glucose metabolisk and blood lipids. ', Clinical Nutrition, vol. 41, 41, pp. 441-451 . https://doi.org/10.1016/j.clnu.2021.12.031
Gürdeniz, G, Uusitupa, M, Hermansen, K, Savolainen, M J, Schwab, U, Kolehmainen, M, Brader, L J, Cloetens, L, Herzig, K-H, Hukkanen, J, Rosqvist, F, Ulven, S M, Gunnarsdóttir, I, Thorsdottir, I, Orešič, M, Poutanen, K S, Risérus, U, Åkesson, B & Dragsted, L O 2022, ' Analysis of the SYSDIET Healthy Nordic Diet randomized trial based on metabolic profiling reveal beneficial effects on glucose metabolism and blood lipids ', Clinical Nutrition, vol. 41, no. 2, pp. 441-451 . https://doi.org/10.1016/j.clnu.2021.12.031
Gürdeniz, G, Uusitupa, M, Hermansen, K, Savolainen, M J, Schwab, U, Kolehmainen, M, Brader, L, Cloetens, L, Herzig, K-H, Hukkanen, J, Rosqvist, F, Ulven, S M, Gunnarsdóttir, I, Thorsdottir, I, Oresic, M, Poutanen, K S, Risérus, U, Åkesson, B & Dragsted, L O 2022, ' Analysis of the SYSDIET Healthy Nordic Diet randomized trial based on metabolic profiling reveal beneficial effects on glucose metabolism and blood lipids ', Clinical Nutrition, vol. 41, no. 2, pp. 441-451 . https://doi.org/10.1016/j.clnu.2021.12.031
Gürdeniz, G, Uusitupa, M, Hermansen, K, Savolainen, M J, Schwab, U, Kolehmainen, M, Brader, L, Cloetens, L, Herzig, K H, Hukkanen, J, Rosqvist, F, Ulven, S M, Gunnarsdóttir, I, Thorsdottir, I, Oresic, M, Poutanen, K S, Risérus, U, Åkesson, B & Dragsted, L O 2022, ' Analysis of the SYSDIET Healthy Nordic Diet randomized trial based on metabolic profiling reveal beneficial effects on glucose metabolism and blood lipids ', Clinical Nutrition, vol. 41, no. 2, pp. 441-451 . https://doi.org/10.1016/j.clnu.2021.12.031
Gürdeniz, G, Uusitupa, M, Hermansen, K, Savolainen, MJ, Schwab, U, Kolehmainen, M, Brader, L J, Cloetens, L, Herzig, K-H, Hukkanen, J, Rosqvist, F, Ulven, SM, Gunnarsdóttir, I, Thorsdottir, I, Oresic, M, Poutanen, KS, Risérus, U, Åkesson, B & Dragsted, L O 2022, ' Analysis of the SYSDIET Healthy Nordic Diet randomized trial based on metabolic profiling reveal beneficial effects on glucose metabolisk and blood lipids. ', Clinical Nutrition, vol. 41, 41, pp. 441-451 . https://doi.org/10.1016/j.clnu.2021.12.031
Gürdeniz, G, Uusitupa, M, Hermansen, K, Savolainen, M J, Schwab, U, Kolehmainen, M, Brader, L J, Cloetens, L, Herzig, K-H, Hukkanen, J, Rosqvist, F, Ulven, S M, Gunnarsdóttir, I, Thorsdottir, I, Orešič, M, Poutanen, K S, Risérus, U, Åkesson, B & Dragsted, L O 2022, ' Analysis of the SYSDIET Healthy Nordic Diet randomized trial based on metabolic profiling reveal beneficial effects on glucose metabolism and blood lipids ', Clinical Nutrition, vol. 41, no. 2, pp. 441-451 . https://doi.org/10.1016/j.clnu.2021.12.031
Gürdeniz, G, Uusitupa, M, Hermansen, K, Savolainen, M J, Schwab, U, Kolehmainen, M, Brader, L, Cloetens, L, Herzig, K-H, Hukkanen, J, Rosqvist, F, Ulven, S M, Gunnarsdóttir, I, Thorsdottir, I, Oresic, M, Poutanen, K S, Risérus, U, Åkesson, B & Dragsted, L O 2022, ' Analysis of the SYSDIET Healthy Nordic Diet randomized trial based on metabolic profiling reveal beneficial effects on glucose metabolism and blood lipids ', Clinical Nutrition, vol. 41, no. 2, pp. 441-451 . https://doi.org/10.1016/j.clnu.2021.12.031
Gürdeniz, G, Uusitupa, M, Hermansen, K, Savolainen, M J, Schwab, U, Kolehmainen, M, Brader, L, Cloetens, L, Herzig, K H, Hukkanen, J, Rosqvist, F, Ulven, S M, Gunnarsdóttir, I, Thorsdottir, I, Oresic, M, Poutanen, K S, Risérus, U, Åkesson, B & Dragsted, L O 2022, ' Analysis of the SYSDIET Healthy Nordic Diet randomized trial based on metabolic profiling reveal beneficial effects on glucose metabolism and blood lipids ', Clinical Nutrition, vol. 41, no. 2, pp. 441-451 . https://doi.org/10.1016/j.clnu.2021.12.031
Background & aims: Intake assessment in multicenter trials is challenging, yet important for accurate outcome evaluation. The present study aimed to characterize a multicenter randomized controlled trial with a healthy Nordic diet (HND) compared to a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::831e24d84a7799f66ef5c2ad3c32aed9
https://cris.vtt.fi/en/publications/7f5e9df4-9375-40eb-a062-4676193c74ee
https://cris.vtt.fi/en/publications/7f5e9df4-9375-40eb-a062-4676193c74ee
Publikováno v:
Polymer Chemistry. 13:3091-3101
A cyanate ester derived from bio-based cardanol was cross-linked at room temperature via synergistic thiol–ene chemistry catalyzed by UV irradiation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f3bfaff3b16d2789c9ae4ac5dc142902
https://doi.org/10.1039/d2py00160h
https://doi.org/10.1039/d2py00160h
Autor:
Natalie Istomin, Mari‐Anne Härma, Ramin Akhi, Antti E. Nissinen, Markku J. Savolainen, Krishna Adeshara, Markku Lehto, Per‐Henrik Groop, Vesa Koivukangas, Janne Hukkanen, Sohvi Hörkkö
Obesity is associated with low-grade inflammation and increased systemic oxidative stress. Roux-en-Y gastric bypass (RYGB) surgery is known to ameliorate the obesity-induced metabolic dysfunctions. We aimed to study the levels of natural antibodies i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa5a81a34f3210035654bc34de32eb39
http://hdl.handle.net/10138/350368
http://hdl.handle.net/10138/350368
Autor:
Timo Paavola, Sanna Kuusisto, Matti Jauhiainen, Sakari Kakko, Tiia Kangas-Kontio, Jari Metso, Pasi Soininen, Mika Ala-Korpela, Risto Bloigu, Minna L Hannuksela, Markku J Savolainen, Tuire Salonurmi
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0171993 (2017)
OBJECTIVE:The potential of high-density lipoproteins (HDL) to facilitate cholesterol removal from arterial foam cells is a key function of HDL. We studied whether cholesterol efflux to serum and HDL subfractions is impaired in subjects with early cor
Externí odkaz:
https://doaj.org/article/711dbca8ab734a5daf70a89a2d7e56f4
Autor:
Satu Vavuli, Tuire Salonurmi, Sirpa Loukovaara, Antti E. Nissinen, Markku J. Savolainen, M. Johanna Liinamaa
Publikováno v:
Journal of Diabetes Research, Vol 2016 (2016)
Aims. This study investigated the association of autoantibodies binding to oxidized low-density lipoproteins (oxLDL) in diabetic retinopathy (DR). Methods. Plasma from 229 types 1 and 2 patients with DR including diabetic macular edema (DME) and prol
Externí odkaz:
https://doaj.org/article/bd25a4bbbb02470ab540ca08d0bbe1ed