Zobrazeno 1 - 10 of 111 pro vyhledávání: '"Markku, Korpela"'
1
Akademický článek
Glycoprotein YKL-40: A potential biomarker of disease activity in rheumatoid arthritis during intensive treatment with csDMARDs and infliximab. Evidence from the randomised controlled NEO-RACo trial.
Autor: Tuija Väänänen, Katriina Vuolteenaho, Hannu Kautiainen, Riina Nieminen, Timo Möttönen, Pekka Hannonen, Markku Korpela, Markku J Kauppi, Kari Laiho, Oili Kaipiainen-Seppänen, Riitta Luosujärvi, Tea Uusitalo, Toini Uutela, Marjatta Leirisalo-Repo, Eeva Moilanen, NEO-RACo Study Group
Publikováno v: PLoS ONE, Vol 12, Iss 8, p e0183294 (2017)
YKL-40, a chitinase-like glycoprotein associated with inflammation and tissue remodeling, is produced by joint tissues and recognized as a candidate auto-antigen in rheumatoid arthritis (RA). In the present study, we investigated YKL-40 as a potentia
Externí odkaz: https://doaj.org/article/6049803f74e6424a87fd85ebba81496f
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2
Akademický článek
The duration of gastrointestinal and joint symptoms after a large waterborne outbreak of gastroenteritis in Finland in 2007--a questionnaire-based 15-month follow-up study.
Autor: Janne Laine, Jukka Lumio, Salla Toikkanen, Mikko J Virtanen, Terhi Uotila, Markku Korpela, Eila Kujansuu, Markku Kuusi
Publikováno v: PLoS ONE, Vol 9, Iss 1, p e85457 (2014)
An extensive drinking water-associated gastroenteritis outbreak took place in the town of Nokia in Southern Finland in 2007. 53% of the exposed came down with gastroenteritis and 7% had arthritis-like symptoms (joint swelling, redness, warmth or pain
Externí odkaz: https://doaj.org/article/5e3c3d8284744cfcb833082c6d64e5e7
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3
Epstein-Barr virus in peripheral blood is associated with response to rituximab therapy in rheumatoid arthritis patients
Autor: Markku Korpela, Markku J Kauppi, Heikki Valleala, Vesa-Petteri Kouri
Publikováno v: Clinical Rheumatology. 34:1485-1488
Autoreactive B cells infected by Epstein-Barr virus (EBV) are suspected to be involved in the etiology of various human chronic autoimmune diseases. This motivated us to study the relationship between peripheral blood EBV load at baseline and treatme
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f7787fe35dba33a2f462c15d8f56c05
https://doi.org/10.1007/s10067-015-2992-0
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5
The activity of JAK-STAT pathways in rheumatoid arthritis: constitutive activation of STAT3 correlates with interleukin 6 levels
Autor: Ilkka Junttila, Markku Korpela, Olli Silvennoinen, Krista-Liisa Vidqvist, P. Isomäki
Publikováno v: Rheumatology. 54:1103-1113
Objective Many cytokines involved in RA activate the Janus kinase-signal transducer and activator of transcription (JAK-STAT) pathways. Therapeutic drugs that inhibit these pathways are being developed for RA. To investigate disease-related alteratio
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0170e6e764c89c02e7cb1be5d115c82b
https://doi.org/10.1093/rheumatology/keu430
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6
ESSPRI and other patient-reported indices in patients with primary Sjogren's syndrome during 100 consecutive outpatient visits at one rheumatological clinic
Autor: Markku Korpela, M. Pertovaara
Publikováno v: Rheumatology. 53:927-931
Objective. A European League Against Rheumatism (EULAR) SS disease activity index (ESSDAI) and a patient-reported index (ESSPRI) have recently been developed and validated. In our previous study the ESSDAI correlated significantly with serum b2 micro
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::615424eeb960fd7eb7a66a4c081e6f01
https://doi.org/10.1093/rheumatology/ket476
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8
Disease activity of idiopathic juvenile arthritis continues through adolescence despite the use of biologic therapies
Autor: Markku Korpela, Krista-Liisa Vidqvist, Merja Malin, Tuire Varjolahti-Lehtinen
Publikováno v: Rheumatology. 52:1999-2003
Objectives To investigate the use of DMARDs and biologic treatments and disease activity in patients with JIA referred to the adult rheumatology clinic and to provide further information regarding the need for long-term rheumatologic care. Methods We
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e7ec1ca72ffabb535aa63eb31070f0b
https://doi.org/10.1093/rheumatology/ket256
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10
Early treatment intensification induces favourable radiographic outcomes according to predicted versus observed radiographic progression in early rheumatoid arthritis: a subanalysis of the randomised FIN-RACo and NEO-RACo trials
Autor: Adrian, Levitsky, Marius C, Wick, Timo, Möttönen, Marjatta, Leirisalo-Repo, Leena, Laasonen, Markku, Korpela, Ronald F, van Vollenhoven, Vappu, Rantalaiho
Publikováno v: Clinical and experimental rheumatology. 34(6)
Predicted versus observed radiographic progression in early rheumatoid arthritis (POPeRA) was applied to demonstrate how various treatment modalities affect and potentially minimise radiographic progression over time.The POPeRA method utilises the ba
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::159477d90cd04bdabd98309c8c35146b
https://pubmed.ncbi.nlm.nih.gov/27607411
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