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pro vyhledávání: '"Markiyan Doliba"'
Autor:
Gerard J. Meskill, Craig W. Davis, Donna Zarycranski, Markiyan Doliba, Jean-Charles Schwartz, Jeffrey M. Dayno
Publikováno v:
CNS Drugs
Background Pitolisant, a selective histamine 3 receptor antagonist/inverse agonist, is indicated for the treatment of excessive daytime sleepiness or cataplexy in adults with narcolepsy. The efficacy and safety of pitolisant have been demonstrated in
Autor:
Audrey Wells, David Albers, Markiyan Doliba, Donna Zarycranski, Jean-Charles Schwartz, Jeffrey Dayno
Publikováno v:
SLEEP. 46:A253-A254
Introduction Narcolepsy is characterized by symptoms indicative of sleep–wake dysregulation, notably excessive daytime sleepiness (EDS) and cataplexy. In 2021, the American Academy of Sleep Medicine (AASM) updated its clinical practice guidelines o
Autor:
Gerard Meskill, Craig Davis, Donna Zarycranski, Markiyan Doliba, Jean-Charles Schwartz, Jeffrey Dayno
Publikováno v:
Sleep. 45:A172-A172
Introduction This post hoc analysis evaluated the clinical impact of pitolisant for the reduction of excessive daytime sleepiness (EDS) and cataplexy in adults with a high burden of narcolepsy symptoms. When evaluating results of randomized, placebo-
Autor:
Markiyan Doliba, Donna Zarycranski, Jean-Charles Schwartz, Jeffrey M Dayno, Gerard J Meskill, Craig W. Davis
Publikováno v:
Sleep. 44:A198-A199
Introduction When evaluating results of randomized, placebo-controlled trials, the clinical impact of a treatment can be assessed using number needed to treat (NNT; number of patients that need to be treated to achieve a specific outcome for one pers