Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Markian S. Jaworsky"'
Publikováno v:
Journal of Chromatography A. 1185:185-193
A novel mixed-mode reversed-phase and cation-exchange high-performance liquid chromatography (HPLC) method is described to simultaneously determine four related impurities of cations, zwitterions and neutral compounds in developmental Drug A. The com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea159c8343895adae744483f94d3324f
https://doi.org/10.1016/j.chroma.2008.01.083
https://doi.org/10.1016/j.chroma.2008.01.083
Autor:
Karin A. Kook, Markian S. Jaworsky, Steve K. Teo, William Tracewell, Michael A. Scheffler, David I. Stirling, Wayne A. Colburn, Steve D. Thomas, Oscar L. Laskin
Publikováno v:
Clinical Pharmacokinetics. 43:311-327
Thalidomide is a racemic glutamic acid derivative approved in the US for erythema nodosum leprosum, a complication of leprosy. In addition, its use in various inflammatory and oncologic conditions is being investigated. Thalidomide interconverts betw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4393f2aa140453d0754ee9d1d9c32b99
https://doi.org/10.2165/00003088-200443050-00004
https://doi.org/10.2165/00003088-200443050-00004
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 31(1)
Thalidomide molecule, a synthetic derivative of glutamine, can undergo hydrolysis at physiologic pH to form glutamine. Additionally, L-glutamine is one of the starting materials in the synthesis of Thalidomide drug substance. The current USP method f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebbc665c3e4f0abf382f4cdbfdd6edaa
https://pubmed.ncbi.nlm.nih.gov/12560045
https://pubmed.ncbi.nlm.nih.gov/12560045