Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Marketa Benkova"'
Autor:
Michaela Hympanova, Saša Terlep, Aneta Markova, Lukáš Prchal, Iztok Dogsa, Lenka Pulkrabkova, Marketa Benkova, Jan Marek, David Stopar
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
An increasing microbial resistance to known antibiotics raises a demand for new antimicrobials. In this study the antimicrobial properties of a series of new N-Alkylpyridinium quaternary ammonium compounds (QACs) with varying alkyl chain lengths were
Externí odkaz:
https://doaj.org/article/a8e6ab4c020744fd993d577e8f5d931d
Autor:
Aneta Markova, Michaela Hympanova, Marek Matula, Lukas Prchal, Radek Sleha, Marketa Benkova, Lenka Pulkrabkova, Ondrej Soukup, Zuzana Krocova, Daniel Jun, Jan Marek
Publikováno v:
Toxics, Vol 9, Iss 9, p 222 (2021)
Benzoxonium chloride belongs to the group of quaternary ammonium salts, which have been widely used for decades as disinfectants because of their high efficacy, low toxicity, and thermal stability. In this study, we have prepared the C10-C18 set of b
Externí odkaz:
https://doaj.org/article/1a87b8e112cc4ff8a44c68c1d61460af
Autor:
Jan Konecny, Anna Misiachna, Martina Hrabinova, Lenka Pulkrabkova, Marketa Benkova, Lukas Prchal, Tomas Kucera, Tereza Kobrlova, Vladimir Finger, Marharyta Kolcheva, Stepan Kortus, Daniel Jun, Marian Valko, Martin Horak, Ondrej Soukup, Jan Korabecny
Publikováno v:
Biomolecules, Vol 11, Iss 1, p 3 (2020)
Alzheimer’s disease (AD) is a complex disorder with unknown etiology. Currently, only symptomatic therapy of AD is available, comprising cholinesterase inhibitors and N-methyl-d-aspartate (NMDA) receptor antagonists. Drugs targeting only one pathol
Externí odkaz:
https://doaj.org/article/d6ee28dbc6f147f48bce851d85867db0
Autor:
Sarka Salajkova, Marketa Benkova, Jan Marek, Radek Sleha, Lukas Prchal, David Malinak, Rafael Dolezal, Kristina Sepčić, Nina Gunde-Cimerman, Kamil Kuca, Ondrej Soukup
Publikováno v:
Molecules, Vol 25, Iss 9, p 2254 (2020)
Nosocomial infections, which greatly increase morbidity among hospitalized patients, together with growing antibiotic resistance still encourage many researchers to search for novel antimicrobial compounds. Picolinium salts with different lengths of
Externí odkaz:
https://doaj.org/article/4cd878c40b944f69ad4c9d84c9b6eb82
Autor:
Jana Janockova, Rafael Dolezal, Eugenie Nepovimova, Tereza Kobrlova, Marketa Benkova, Kamil Kuca, Jan Konecny, Eva Mezeiova, Michaela Melikova, Vendula Hepnarova, Avi Ring, Ondrej Soukup, Jan Korabecny
Publikováno v:
Molecules, Vol 23, Iss 11, p 2926 (2018)
The neuropeptides, orexin A and orexin B (also known as hypocretins), are produced in hypothalamic neurons and belong to ligands for orphan G protein-coupled receptors. Generally, the primary role of orexins is to act as excitatory neurotransmitters
Externí odkaz:
https://doaj.org/article/5d196cdbcad34cc5a090e956de18bdd5
Autor:
Ondrej Soukup, Filip Havel, Marketa Benkova, J. Proska, Lukas Prchal, Sarka Salajkova, Rafael Dolezal, Kamil Kuca, Zdenek Hodny, Michal Sramek, Monika Zarska, David Malinak, Filip Novotny, Kamil Musilek, Jiri Bartek
Publikováno v:
International Journal of Nanomedicine
Sarka Salajkova,1,2 Filip Havel,1,3 Michal Sramek,1 Filip Novotny,1,4 David Malinak,2,5 Rafael Dolezal,2,5 Lukas Prchal,2 Marketa Benkova,2 Ondrej Soukup,2 Kamil Musilek,2,5 Kamil Kuca,2,5 Jiri Bartek,1,6,7 Jan Proska,3 Monika Zarska,1 Zdenek Hodny1
Publikováno v:
Journal of Applied Microbiology. 129:806-822
Rapid identification of pathogen and its resistance to antimicrobial drugs, and subsequent appropriate antimicrobial treatment are essential for correct patient outcomes. Conventional detection methods of bacterial resistance, such as disc diffusion,
Autor:
Radek Sleha, Nina Gunde-Cimerman, Marketa Benkova, Rafael Dolezal, Kristina Sepčić, Lukas Prchal, Martin Novák, Ondrej Soukup, Tina Eleršek, Vanda Bostik, Jan Marek, Pavel Boštík
Publikováno v:
ChemistrySelect. 4:12076-12084
Autor:
Ondrej Soukup, Marketa Benkova, Aneta Markova, Lenka Pulkrabkova, Radek Sleha, Daniel Jun, Michaela Hympanova, Lukas Prchal, Marek Matula, Jan Marek, Zuzana Krocova
Publikováno v:
Toxics
Toxics; Volume 9; Issue 9; Pages: 222
Toxics, Vol 9, Iss 222, p 222 (2021)
Toxics; Volume 9; Issue 9; Pages: 222
Toxics, Vol 9, Iss 222, p 222 (2021)
Benzoxonium chloride belongs to the group of quaternary ammonium salts, which have been widely used for decades as disinfectants because of their high efficacy, low toxicity, and thermal stability. In this study, we have prepared the C10-C18 set of b
Autor:
Marketa Benkova, Michal Novotny, Adam Skarka, Tamara Zorbaz, Antonio Zandona, Ondrej Soukup, Zrinka Kovarik, Maja Katalinić, Nikolina Maček Hrvat, David Malinak, Nikola Maraković, Kamil Musilek, Kamil Kuca, Rudolf Andrys
Publikováno v:
Journal of Medicinal Chemistry. 61:10753-10766
Six chlorinated bispyridinium mono-oximes, analogous to potent charged reactivators K027, K048, and K203, were synthesized with the aim of improving lipophilicity and reducing the pKa value of the oxime group, thus resulting in a higher oximate conce