Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Marketa, Vancurova"'
Autor:
Patrik Oleksak, Miroslav Psotka, Marketa Vancurova, Olena Sapega, Jana Bieblova, Milan Reinis, David Rysanek, Romana Mikyskova, Katarina Chalupova, David Malinak, Jana Svobodova, Rudolf Andrys, Helena Rehulkova, Vojtech Skopek, Pham Ngoc Lam, Jiri Bartek, Zdenek Hodny, Kamil Musilek
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 36, Iss 1, Pp 410-424 (2021)
Twelve novel analogs of STAT3 inhibitor BP-1-102 were designed and synthesised with the aim to modify hydrophobic fragments of the molecules that are important for interaction with the STAT3 SH2 domain. The cytotoxic activity of the reference and nov
Externí odkaz:
https://doaj.org/article/cfac0c0e4320428ab38cfae14e7c28f8
Autor:
Miroslav Pribyl, Sona Hubackova, Alena Moudra, Marketa Vancurova, Helena Polackova, Tomas Stopka, Anna Jonasova, Radka Bokorova, Ota Fuchs, Jan Stritesky, Barbora Salovska, Jiri Bartek, Zdenek Hodny
Publikováno v:
Molecular Oncology, Vol 14, Iss 10, Pp 2403-2419 (2020)
Myelodysplastic syndromes (MDS) are preleukemic disorders characterized by clonal growth of mutant hematopoietic stem and progenitor cells. MDS are associated with proinflammatory signaling, dysregulated immune response, and cell death in the bone ma
Externí odkaz:
https://doaj.org/article/fb9c612ae072482e8ba012c2ca32f842
Autor:
Ota Fuchs, Anna Jonasova, Marketa Vancurova, Jiri Bartek, Radka Bokorova, Sona Hubackova, Zdenek Hodny, Alena Moudra, Tomas Stopka, Barbora Salovska, Jan Stritesky, Helena Polackova, Miroslav Pribyl
Publikováno v:
Molecular Oncology, Vol 14, Iss 10, Pp 2403-2419 (2020)
Molecular Oncology
Molecular Oncology
Aberrantly expressed suprabasin (SBSN) is a novel biomarker in myelodysplastic syndrome (MDS) patients. The highest levels of SBSN, secreted from myeloid subpopulations, including myeloid‐derived suppressor cells, are detectable within bone marrow
Autor:
Lucie Knoblochova, Marketa Vancurova, Jan Kosla, Jiri Bartek, Kamila Burdova, Dusana Majera, Martin Mistrik, Zdenek Hodny, Hana Hanzlikova
Publikováno v:
DNA Repair. 78:114-127
The bulk of DNA damage caused by ionizing radiation (IR) is generally repaired within hours, yet a subset of DNA lesions may persist even for long periods of time. Such persisting IR-induced foci (pIRIF) co-associate with PML nuclear bodies (PML-NBs)
Autor:
Patrik, Oleksak, Miroslav, Psotka, Marketa, Vancurova, Olena, Sapega, Jana, Bieblova, Milan, Reinis, David, Rysanek, Romana, Mikyskova, Katarina, Chalupova, David, Malinak, Jana, Svobodova, Rudolf, Andrys, Helena, Rehulkova, Vojtech, Skopek, Pham, Ngoc Lam, Jiri, Bartek, Zdenek, Hodny, Kamil, Musilek
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Twelve novel analogs of STAT3 inhibitor BP-1-102 were designed and synthesised with the aim to modify hydrophobic fragments of the molecules that are important for interaction with the STAT3 SH2 domain. The cytotoxic activity of the reference and nov
Autor:
David Malinak, Pham Ngoc Lam, Marketa Vancurova, Romana Mikyšková, Vojtech Skopek, Kamil Musilek, Jana Svobodova, Helena Rehulkova, Zdenek Hodny, Miroslav Psotka, Milan Reinis, Olena Sapega, Jiri Bartek, Katarina Chalupova, Rudolf Andrys, David Rysanek, Patrik Oleksak, Jana Bieblová
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 36, Iss 1, Pp 410-424 (2021)
Twelve novel analogs of STAT3 inhibitor BP-1-102 were designed and synthesised with the aim to modify hydrophobic fragments of the molecules that are important for interaction with the STAT3 SH2 domain. The cytotoxic activity of the reference and nov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8cac5c92173998608c522cc3e9dc3be
Autor:
Jiri Bartek, Hilal Saran, J. Proska, Zuzana Hvezdova, Rastislav Dzijak, Michal Novotny, Filip Havel, Katerina Krejcikova, Michal Sramek, Monika Zarska, Lenka Kyjacova, Andrea Babelova, Filip Novotny, Blanka Gabajova, Marketa Vancurova, Oldrich Benada, Kamil Kuca, Hana Hanzlikova, Zdenek Hodny, Kamil Musilek
Publikováno v:
Bioconjugate Chemistry. 27:2558-2574
Cationic colloidal gold nanorods (GNRs) have a great potential as a theranostic tool for diverse medical applications. GNRs’ properties such as cellular internalization and stability are determined by physicochemical characteristics of their surfac
Publikováno v:
British journal of haematology. 184(2)
Autor:
Pavel Hozák, Sona Hubackova, Zdenek Hodny, Jana Dobrovolna, Zuzana Horejsi, L Janderova-Rossmeislova, Zora Novakova, Pavla Vasicova, Marketa Vancurova, Martin Kosar, Jiri Bartek
Publikováno v:
Oncogene
Oncogene; Vol 29
Oncogene; Vol 29
Cellular senescence guards against cancer and modulates aging; however, the underlying mechanisms remain poorly understood. Here, we show that genotoxic drugs capable of inducing premature senescence in normal and cancer cells, such as 5-bromo-2'-deo
Autor:
Veronika Machalova, Anna Jonasova, Jiri Bartek, Marketa Vancurova, Zdenek Hodny, Alena Moudra, Sona Hubackova, Milan Reiniš
Publikováno v:
OncoImmunology. 5:e1183860
Myelodysplastic syndromes (MDS) represent a heterogeneous group of clonal stem cell disorders characterized by ineffective hematopoiesis frequently progressing into acute myeloid leukemia (AML), with emerging evidence implicating aberrant bone marrow