Zobrazeno 1 - 10
of 517
pro vyhledávání: '"Mark. T. Dransfield"'
Autor:
R. Chad Wade, Takudzwa Mkorombindo, Sharon X. Ling, Erika. S. Helgeson, David M. MacDonald, Krystle Pew, Helen Voelker, Vera Bittner, Ken M. Kunisaki, Matthew R. Lammi, Mark. T. Dransfield
Publikováno v:
BMC Pulmonary Medicine, Vol 23, Iss 1, Pp 1-8 (2023)
Abstract Rationale Pulmonary hypertension (PH) in COPD confers increased risk of exacerbations (ECOPD). Electrocardiogram (ECG) indicators of PH are prognostic both in PH and COPD. In the Beta-Blockers for the Prevention of Acute Exacerbations of COP
Externí odkaz:
https://doaj.org/article/6ed5fa44150a45abae40378220b57c83
Autor:
Ava C. Wilson, Jessica M. Bon, Stephanie Mason, Alejandro A. Diaz, Sharon M. Lutz, Raul San Jose Estepar, Gregory L. Kinney, John E. Hokanson, Stephen I. Rennard, Richard Casaburi, Surya P. Bhatt, Marguerite R. Irvin, Craig P. Hersh, Mark T. Dransfield, George R. Washko, Elizabeth A. Regan, Merry-Lynn McDonald
Publikováno v:
Respiratory Research, Vol 23, Iss 1, Pp 1-9 (2022)
Abstract Background Chronic obstructive pulmonary disease (COPD) is a disease of accelerated aging and is associated with comorbid conditions including osteoporosis and sarcopenia. These extrapulmonary conditions are highly prevalent yet frequently u
Externí odkaz:
https://doaj.org/article/345d28bdacd44f73bb108a81e9a907e3
Autor:
Anne E. Dixon, Kathryn V. Blake, Emily A. DiMango, Mark T. Dransfield, Laura C. Feemster, Olivia Johnson, Gem Roy, Heather Hazucha, Jean Harvey, Meredith C. McCormack, Robert A. Wise, Janet T. Holbrook
Publikováno v:
Obesity Science & Practice, Vol 7, Iss 6, Pp 682-689 (2021)
Abstract Objective There is a high prevalence of obesity in people with asthma, and obesity is associated with poorly controlled asthma. Significant weight loss might improve asthma control: the purpose of this study was to investigate patient charac
Externí odkaz:
https://doaj.org/article/f632f0d7b593481389baed1a3f03369d
Autor:
Mark T. Dransfield, Gerard J. Criner, David M. G. Halpin, MeiLan K. Han, Benjamin Hartley, Ravi Kalhan, Peter Lange, David A. Lipson, Fernando J. Martinez, Dawn Midwinter, Dave Singh, Robert Wise, Ken M. Kunisaki
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 18 (2022)
Background The association between chronic obstructive pulmonary disease exacerbations and increased cardiovascular event risk has not been adequately studied in a heterogenous population with both low and high cardiovascular risk. Methods and Result
Externí odkaz:
https://doaj.org/article/46efbc8b56c04707b552178cb09aa270
Autor:
Dave Singh, Gerard J. Criner, Mark T. Dransfield, David M. G. Halpin, MeiLan K. Han, Peter Lange, Sally Lettis, David A. Lipson, David Mannino, Neil Martin, Fernando J. Martinez, Bruce E. Miller, Robert Wise, Chang-Qing Zhu, David Lomas
Publikováno v:
Respiratory Research, Vol 22, Iss 1, Pp 1-14 (2021)
Abstract Background Fibrinogen is the first qualified prognostic/predictive biomarker for exacerbations in patients with chronic obstructive pulmonary disease (COPD). The IMPACT trial investigated fluticasone furoate/umeclidinium/vilanterol (FF/UMEC/
Externí odkaz:
https://doaj.org/article/e7d5870221044540b62b3afe78882438
Autor:
Kristopher Opron, Lesa A. Begley, John R. Erb-Downward, Christine Freeman, Siddharth Madapoosi, Neil E. Alexis, Igor Barjaktarevic, R. Graham Barr, Eugene R. Bleecker, Russell P. Bowler, Stephanie A. Christenson, Alejandro P. Comellas, Christopher B. Cooper, David J. Couper, Claire M. Doerschuk, Mark T. Dransfield, MeiLan K. Han, Nadia N. Hansel, Annette T. Hastie, Eric A. Hoffman, Robert J. Kaner, Jerry Krishnan, Wanda K. O’Neal, Victor E. Ortega, Robert Paine, Stephen P. Peters, J. Michael Wells, Prescott G. Woodruff, Fernando J. Martinez, Jeffrey L. Curtis, Gary B. Huffnagle, Yvonne J. Huang
Publikováno v:
npj Biofilms and Microbiomes, Vol 7, Iss 1, Pp 1-10 (2021)
Abstract Chronic obstructive pulmonary disease (COPD) is heterogeneous in development, progression, and phenotypes. Little is known about the lung microbiome, sampled by bronchoscopy, in milder COPD and its relationships to clinical features that ref
Externí odkaz:
https://doaj.org/article/10a254afe79640d29b0d02561b498bb0
Publikováno v:
Immunity & Ageing, Vol 17, Iss 1, Pp 1-9 (2020)
Abstract Background There is increasing recognition of the significance of chronic, low-level inflammation in older adults, or “inflammaging.” Innate immune responses and host-bacterial interactions are recognized as key factors in inflammaging.
Externí odkaz:
https://doaj.org/article/8e6b3f8653664882bd5fe4552e6d3d88
Autor:
Ava C. Wilson, Preeti L. Kumar, Sool Lee, Margaret M. Parker, Itika Arora, Jarrett D. Morrow, Emiel F. M. Wouters, Richard Casaburi, Stephen I. Rennard, David A. Lomas, Alvar Agusti, Ruth Tal-Singer, Mark T. Dransfield, J. Michael Wells, Surya P. Bhatt, George Washko, Victor J. Thannickal, Hemant K. Tiwari, Craig P. Hersh, Peter J. Castaldi, Edwin K. Silverman, Merry-Lynn N. McDonald
Publikováno v:
Respiratory Research, Vol 21, Iss 1, Pp 1-9 (2020)
Abstract Introduction Cachexia contributes to increased mortality and reduced quality of life in Chronic Obstructive Pulmonary Disease (COPD) and may be associated with underlying gene expression changes. Our goal was to identify differential gene ex
Externí odkaz:
https://doaj.org/article/8fe83349e7e14355b35989dbedb0784d
Autor:
Robert A. Wise, Mona Bafadhel, Courtney Crim, Gerard J. Criner, Nicola C. Day, David M.G. Halpin, MeiLan K. Han, Peter Lange, David A. Lipson, Fernando J. Martinez, Diego J. Maselli, Dawn Midwinter, Dave Singh, Maeva Zysman, Mark T. Dransfield, Richard E.K. Russell
Publikováno v:
European Respiratory Review, Vol 30, Iss 162 (2021)
Inhaled corticosteroids (ICS) have a class effect of increasing pneumonia risk in patients with COPD. However, pneumonia incidence varies widely across clinical trials of ICS use in COPD. This review clarifies methodological differences in defining a
Externí odkaz:
https://doaj.org/article/d3cb3ba2c1014707b22a384092f3fa36
Autor:
Mercedes Carnethon, Mark T Dransfield, Mary B Rice, George R Washko, MeiLan K Han, Gerard Criner, Charlie Strange, Sonali Bose, Raul San Jose Estepar, Barry Make, Alejandro P. Comellas, Linda Rogers, Ravi Kalhan, Mario Castro, Nadia Hansel, Robert A. Wise, Elliot Israel, Joan Reibman, Murray Mittleman, Philip Diaz, Sandhya Khurana, Paul A Reyfman, Elizabeth Sugar, Heather Hazucha, Jenny Hixon, Curt Reynolds, Emily Dimango, Robert J. Kaner, Loretta G. Que, Jason Lang, Kathryn Blake, Allan J. Dozor, Jeremy Weingarten, James Moy, Michael Busk, Lynn B. Gerald, Monica Kraft, Igor Barjaktarevic, Stephen C. Lazarus, Edward T. Naureckas, Richard W. Vandivier, James Cury, Jerry A. Krishnan, M. Bradley Drummond, Frank C. Sciurba, Charles Irvin, Laura Feemster, Loren C. Denlinger, Katherine Cahill, Wendy C. Moore, William C. Bailey, Janet Holbrook, Alexandra Sierra, Susan Rappaport, Albert Rizzo
Publikováno v:
BMJ Open, Vol 11, Iss 7 (2021)
Introduction The current framework for investigating respiratory diseases is based on defining lung health as the absence of lung disease. In order to develop a comprehensive approach to prevent the development of lung disease, there is a need to eva
Externí odkaz:
https://doaj.org/article/845eb8dd802a4d58963578bea8682a4a