Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Mark Youles"'
Publikováno v:
Methods in Molecular Biology ISBN: 9781071631300
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db453af74489eaedc6b5175f6b78f9d3
https://doi.org/10.1007/978-1-0716-3131-7_16
https://doi.org/10.1007/978-1-0716-3131-7_16
Autor:
Adam R. Bentham, Juan Carlos De la Concepcion, Javier Vega Benjumea, Sally Jones, Melanie Mendel, Jack Stubbs, Clare E. M. Stevenson, Josephine H.R. Maidment, Mark Youles, Jiorgos Kourelis, Rafał Zdrzałek, Sophien Kamoun, Mark J. Banfield
SummaryEngineering expanded effector recognition in plant immune receptors is a promising prospect for generating new disease resistant crop varieties. However, modification of plant NLR receptors has proven challenging due to the lack of understandi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5120b571659208dfb46e9701effc66ed
https://doi.org/10.1101/2022.10.10.511592
https://doi.org/10.1101/2022.10.10.511592
Autor:
Mark Youles, Freya A. Varden, M. N. Mendel, Mark J. Banfield, Adam R. Bentham, J. C. De la Concepcion
The ability to recombinantly produce target proteins is essential to many biochemical, structural, and biophysical assays that allow for interrogation of molecular mechanisms behind protein function. Purification and solubility tags are routinely use
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::316784c5604f3b3b5697a9d279713025
https://doi.org/10.1101/2021.08.10.455798
https://doi.org/10.1101/2021.08.10.455798
Autor:
Hannah Brown, Mark Youles, Amey Redkar, Jonathan D. G. Jones, Hee-Kyung Ahn, Laurence Tomlinson, Yan Ma, Pingtao Ding, Bruno Pok Man Ngou
Publikováno v:
Journal of Experimental Botany
Inducible expression of AvrRps4 activates RRS1/RPS4-mediated effector-triggered immunity without the presence of pathogens, allowing us to characterize downstream immune responses triggered by TIR-NLRs without cell surface receptor-mediated immunity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5f05f7ba00860c147d1cba669660dc8
Autor:
Sylvestre Marillonnet, Nicola J. Patron, Tim-Martin Ehnert, Jonathan D. G. Jones, Ramona Gruetzner, Stefan Werner, Mark Youles, Carola Engler
Publikováno v:
ACS Synthetic Biology. 3:839-843
Plant Synthetic Biology requires robust and efficient methods for assembling multigene constructs. Golden Gate cloning provides a precision module-based cloning technique for facile assembly of multiple genes in one construct. We present here a versa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::751d77682f0c895a080ac36b3d58a298
https://doi.org/10.1021/sb4001504
https://doi.org/10.1021/sb4001504
Engineering the NK1 Fragment of Hepatocyte Growth Factor/Scatter Factor as a MET Receptor Antagonist
Autor:
Simona Stivala, Oliver Holmes, Ermanno Gherardi, Dmitri I. Svergun, Mark Youles, Merel A. Nessen, Maxim V. Petoukhov
Publikováno v:
Journal of Molecular Biology. 377:616-622
The growth and motility factor hepatocyte growth factor/scatter factor (HGF/SF) and its receptor MET, the tyrosine kinase encoded by the c-MET proto-oncogene, exert major roles in cancer invasion and metastasis and are key targets for therapy. NK1 is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b457fb4c6e4bbc8c8be6cfba7f24df4c
https://doi.org/10.1016/j.jmb.2008.01.034
https://doi.org/10.1016/j.jmb.2008.01.034
Autor:
Patrick M. Shih, Alison G. Smith, Guru V. Radhakrishnan, Aymeric Leveau, Paul F. South, Brande B. H. Wulff, Alain Tissier, Gemma Farré, Asaph Aharoni, Michael K. Udvardi, Nicola J. Patron, Alex A. R. Webb, Björn Hamberger, Sylvestre Marillonnet, Katherine J. Denby, Pierre-Marc Delaux, Jonathan D. G. Jones, Sarah E. O'Connor, James A. H. Murray, H. Peter van Esse, David C. Baulcombe, Hannah Kuhn, Diego Orzaez, Paul D. Fraser, Thomas P. Brutnell, Dale Sanders, Christian Rogers, Cyril Zipfel, Jens Stougaard, Julian M. Hibberd, Jim Ajioka, Christine A. Raines, Jane A. Langdale, Cathie Martin, Heiko Rischer, Anne Osbourn, Jean-Michel Ané, Antonio Granell, Sophien Kamoun, Colette Matthewman, Heribert Warzecha, Vardis Ntoukakis, W. Paul Quick, Andy Breakspear, Dominique Loqué, Samantha Fox, Sebastian Schornack, Mark Youles, Ben Miller, Robert A. Field, Harro J. Bouwmeester, Jim Haseloff, Giles E. D. Oldroyd, Oleg Raitskin, James C. W. Locke, Keith J. Edwards, Patrick Schäfer, Silke Robatzek
Publikováno v:
RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
instname
New Phytologist
Patron, N J, Orzaez, D, Marillonnet, S, Warzecha, H, Matthewman, C, Youles, M, Raitskin, O, Leveau, A, Farré, G, Rogers, C, Smith, A, Hibberd, J, Webb, A A R, Locke, J, Schornack, S, Ajioka, J, Baulcombe, D C, Zipfel, C, Kamoun, S, Jones, J D G, Kuhn, H, Robatzek, S, Van Esse, H P, Sanders, D, Oldroyd, G, Martin, C, Field, R, O'Connor, S, Fox, S, Wulff, B, Miller, B, Breakspear, A, Radhakrishnan, G, Delaux, P-M, Loqué, D, Granell, A, Tissier, A, Shih, P, Brutnell, T P, Quick, W P, Rischer, H, Fraser, P D, Aharoni, A, Raines, C, South, P F, Ané, J-M, Hamberger, B R, Langdale, J, Stougaard, J & Bouwmeester, H 2015, ' Standards for plant synthetic biology : A common syntax for exchange of DNA parts ', New Phytologist, vol. 208, no. 1, pp. 13-19 . https://doi.org/10.1111/nph.13532
New Phytologist 208 (2015) 1
New Phytologist, 208(1), 13-19
Patron, N J, Orzaez, D, Marillonnet, S, Warzecha, H, Matthewman, C, Youles, M, Raitskin, O, Leveau, A, Farré, G, Rogers, C, Smith, A, Hibberd, J, Webb, A A R, Locke, J, Schornack, S, Ajioka, J, Baulcombe, D C, Zipfel, C, Kamoun, S, Jones, J D G, Kuhn, H, Robatzek, S, Van Esse, H P, Sanders, D, Oldroyd, G, Martin, C, Field, R, O'Connor, S, Fox, S, Wulff, B, Miller, B, Breakspear, A, Radhakrishnan, G, Delaux, P-M, Loqué, D, Granell, A, Tissier, A, Shih, P, Brutnell, T P, Quick, W P, Rischer, H, Fraser, P D, Aharoni, A, Raines, C, South, P F, Ané, J-M, Hamberger, B R, Langdale, J, Stougaard, J, Bouwmeester, H, Udvardi, M, Murray, J A H, Ntoukakis, V, Schäfer, P, Denby, K, Edwards, K J, Osbourn, A & Haseloff, J 2015, ' Standards for plant synthetic biology : a common syntax for exchange of DNA parts ', New Phytologist, vol. 208, no. 1, pp. 13-9 . https://doi.org/10.1111/nph.13532
instname
New Phytologist
Patron, N J, Orzaez, D, Marillonnet, S, Warzecha, H, Matthewman, C, Youles, M, Raitskin, O, Leveau, A, Farré, G, Rogers, C, Smith, A, Hibberd, J, Webb, A A R, Locke, J, Schornack, S, Ajioka, J, Baulcombe, D C, Zipfel, C, Kamoun, S, Jones, J D G, Kuhn, H, Robatzek, S, Van Esse, H P, Sanders, D, Oldroyd, G, Martin, C, Field, R, O'Connor, S, Fox, S, Wulff, B, Miller, B, Breakspear, A, Radhakrishnan, G, Delaux, P-M, Loqué, D, Granell, A, Tissier, A, Shih, P, Brutnell, T P, Quick, W P, Rischer, H, Fraser, P D, Aharoni, A, Raines, C, South, P F, Ané, J-M, Hamberger, B R, Langdale, J, Stougaard, J & Bouwmeester, H 2015, ' Standards for plant synthetic biology : A common syntax for exchange of DNA parts ', New Phytologist, vol. 208, no. 1, pp. 13-19 . https://doi.org/10.1111/nph.13532
New Phytologist 208 (2015) 1
New Phytologist, 208(1), 13-19
Patron, N J, Orzaez, D, Marillonnet, S, Warzecha, H, Matthewman, C, Youles, M, Raitskin, O, Leveau, A, Farré, G, Rogers, C, Smith, A, Hibberd, J, Webb, A A R, Locke, J, Schornack, S, Ajioka, J, Baulcombe, D C, Zipfel, C, Kamoun, S, Jones, J D G, Kuhn, H, Robatzek, S, Van Esse, H P, Sanders, D, Oldroyd, G, Martin, C, Field, R, O'Connor, S, Fox, S, Wulff, B, Miller, B, Breakspear, A, Radhakrishnan, G, Delaux, P-M, Loqué, D, Granell, A, Tissier, A, Shih, P, Brutnell, T P, Quick, W P, Rischer, H, Fraser, P D, Aharoni, A, Raines, C, South, P F, Ané, J-M, Hamberger, B R, Langdale, J, Stougaard, J, Bouwmeester, H, Udvardi, M, Murray, J A H, Ntoukakis, V, Schäfer, P, Denby, K, Edwards, K J, Osbourn, A & Haseloff, J 2015, ' Standards for plant synthetic biology : a common syntax for exchange of DNA parts ', New Phytologist, vol. 208, no. 1, pp. 13-9 . https://doi.org/10.1111/nph.13532
[EN] Inventors in the field of mechanical and electronic engineering can access multitudes of components and, thanks to standardization, parts from different manufacturers can be used in combination with each other. The introduction of BioBrick stand
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f66cf9ac5f018590d9639213795cc717
https://www.repository.cam.ac.uk/handle/1810/293594
https://www.repository.cam.ac.uk/handle/1810/293594
Autor:
Ulf Skoglund, Dmitri I. Svergun, Ermanno Gherardi, Mark Youles, Maxim V. Petoukhov, John T. Finch, Tom L. Blundell, Ricardo Núñez Miguel, George F. Vande Woude, Sara Sandin, Lars-Göran Öfverstedt
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America 103, 4051 (2006). doi:10.1073/pnas.0509040103
The polypeptide growth factor, hepatocyte growth factor/scatter factor (HGF/SF), shares the multidomain structure and proteolytic mechanism of activation of plasminogen and other complex serine proteinases. HGF/SF, however, has no enzymatic activity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ead198c5aff57e083edcf61fff05ea46
https://doi.org/10.1073/pnas.0509040103
https://doi.org/10.1073/pnas.0509040103
Autor:
Gemma Farré, Sylvestre Marillonnet, Oleg Raitskin, Colette Matthewman, Mark Youles, Orzaez O, Heribert Warzecha, Nicola J. Patron, Aymeric Leveau, Christian Rogers
Publikováno v:
New Phytologist. 209:885-885
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6bfefb961705505074b6d1bd402a767a
https://doi.org/10.1111/nph.13773
https://doi.org/10.1111/nph.13773
Autor:
Tom L. Blundell, Julian Gough, Ermanno Gherardi, Ricardo Núñez Miguel, G. Hartmann, A. Bandyopadhyay, Mark Youles, L. Iamele, P.J.G. Butler
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 100(21)
Little is known about the large ectodomain of MET, the product of the c- met protooncogene and receptor for hepatocyte growth factor/scatter factor (HGF/SF). Here, we establish by deletion mutagenesis that the HGF/SF and heparin-binding sites of MET
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbaa085101f8d485adaeef1d123a55db
https://pubmed.ncbi.nlm.nih.gov/14528000
https://pubmed.ncbi.nlm.nih.gov/14528000