Zobrazeno 1 - 10
of 106
pro vyhledávání: '"Mark Westerman"'
Autor:
Miklós Krepuska, Balázs Mayer, Lynn Vitale-Cross, Vamsee D. Myneni, Michael K. Boyajian, Krisztián Németh, Ildikó Szalayova, Ted Cho, Ian McClain-Caldwell, Aaron D. Gingerich, Huiling Han, Mark Westerman, Balázs Rada, Éva Mezey
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Bone marrow stromal cells (BMSCs) have immunomodulatory activities in numerous species and have been used in clinical trials. BMSCs also make antibacterial agents. Since hepcidin is known to have antimicrobial effects in fish, we wondered if
Externí odkaz:
https://doaj.org/article/378ae074006346b892d1a7c0bf4c6776
Publikováno v:
BMC Nephrology, Vol 19, Iss 1, Pp 1-8 (2018)
Abstract Background Anemia is highly prevalent in chronic kidney disease (CKD). Elevated hepcidin concentrations are an important mediator of disordered iron metabolism, a key mechanism underlying anemia of CKD. Vitamin D was recently shown to reduce
Externí odkaz:
https://doaj.org/article/f03f4643a1ff4670a7e3509a693ec14f
Autor:
Huiyong Chen, Tenzin Choesang, Huihui Li, Shuming Sun, Petra Pham, Weili Bao, Maria Feola, Mark Westerman, Guiyuan Li, Antonia Follenzi, Lionel Blanc, Stefano Rivella, Robert E. Fleming, Yelena Z. Ginzburg
Publikováno v:
Haematologica, Vol 101, Iss 3 (2016)
Iron overload results in significant morbidity and mortality in β-thalassemic patients. Insufficient hepcidin is implicated in parenchymal iron overload in β-thalassemia and approaches to increase hepcidin have therapeutic potential. We have previo
Externí odkaz:
https://doaj.org/article/17baf8f3fd334df0aa5848370955ccf7
Publikováno v:
Croatian Journal of Fisheries, Vol 70, Iss 3, Pp 93-110 (2012)
Hybrid striped bass (42.6+4.9 g wet wt; 139.3+6.1 mm length), were randomly stocked into one of 6 tanks (n=6 tank-1) of a custom designed, recirculating life support system (RLSS). Water quality was as follows: DO2 (6.50.6 mg l-1), pH (7.70.5),
Externí odkaz:
https://doaj.org/article/4444e6179aa14860bf989a5de35e8b35
Autor:
Lisa Tussing-Humphreys, Keith N. Frayn, Steven R. Smith, Mark Westerman, A. Louise Dennis, Elizabeta Nemeth, Jessica Thomson, Cenk Pusatcioglu
Publikováno v:
The Scientific World Journal, Vol 11, Pp 2197-2206 (2011)
Hepcidin is the main regulator of systemic iron homeostasis and is primarily produced by the liver but is also expressed, at the mRNA-level, in periphery tissues including the subcutaneous and visceral adipose tissue. Obesity is associated with eleva
Externí odkaz:
https://doaj.org/article/b6248774e862411db8559a171b5bf751
Autor:
Patrick Gutschow, Paul J. Schmidt, Huiling Han, Vaughn Ostland, Thomas B. Bartnikas, Michael A. Pettiglio, Carolina Herrera, James S. Butler, Elizabeta Nemeth, Tomas Ganz, Mark D. Fleming, Mark Westerman
Publikováno v:
Haematologica, Vol 100, Iss 2 (2015)
Mice have been essential for distinguishing the role of hepcidin in iron homeostasis. Currently, investigators monitor levels of murine hepatic hepcidin-1 mRNA as a surrogate marker for the bioactive hepcidin protein itself. Here, we describe and val
Externí odkaz:
https://doaj.org/article/a7cdea950c13493eaf90e1216e2d2d6c
Autor:
Alan E. Mast, Karen S. Schlumpf, David J. Wright, Bryce Johnson, Simone A. Glynn, Michael P. Busch, Gordana Olbina, Mark Westerman, Elizabeta Nemeth, Tomas Ganz
Publikováno v:
Haematologica, Vol 98, Iss 8 (2013)
Dietary iron absorption is regulated by hepcidin, an iron regulatory protein produced by the liver. Hepcidin production is regulated by iron stores, erythropoiesis and inflammation, but its physiology when repeated blood loss occurs has not been char
Externí odkaz:
https://doaj.org/article/889356f1d67d4daa90bc02bd4e5c40b9
Autor:
Sant-Rayn Pasricha, Zoe McQuilten, Mark Westerman, Anthony Keller, Elizabeta Nemeth, Tomas Ganz, Erica Wood
Publikováno v:
Haematologica, Vol 96, Iss 8 (2011)
Background Currently used indicators of iron status have limitations. Hepcidin, a key regulator of iron metabolism, is reduced in iron deficiency. We sought to determine the properties of hepcidin as a diagnostic test of iron deficiency.Design and Me
Externí odkaz:
https://doaj.org/article/2b0eba4875d14fbe93051672b0af6a64
Autor:
Domenico Girelli, Paola Trombini, Fabiana Busti, Natascia Campostrini, Marco Sandri, Sara Pelucchi, Mark Westerman, Tomas Ganz, Elizabeta Nemeth, Alberto Piperno, Clara Camaschella
Publikováno v:
Haematologica, Vol 96, Iss 4 (2011)
Background Inadequate hepcidin production leads to iron overload in nearly all types of hemochromatosis. We explored the acute response of hepcidin to iron challenge in 25 patients with HFE-hemochromatosis, in two with TFR2-hemochromatosis and in 13
Externí odkaz:
https://doaj.org/article/2a78c75e22c1484aacc8938663bca537
Autor:
Ann-Kathrin Eisfeld, Mark Westerman, Rainer Krahl, Sabine Leiblein, Uwe Gerd Liebert, Marianne Hehme, Daniel Teupser, Dietger Niederwieser, Haifa Kathrin Al-Ali
Publikováno v:
Advances in Hematology, Vol 2011 (2011)
Hepcidin is upregulated by inflammation and iron. Inherited (HFE genotype) and treatment-related factors (blood units (BU), Iron overload) affecting hepcidin (measured by C-ELISA) were studied in 42 consecutive patients with AML prior to and after al
Externí odkaz:
https://doaj.org/article/f16486f51ee0486e9987fbfcdc0876ba