Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Mark W.M. Schellings"'
Autor:
Tim Hesselink, Georgios J. Vlachojannis, Antoinette Milané-Santman, Johannes G. Krabbe, Marcoen F. Scholten, Evelien W.M. Kemna, Mark W.M. Schellings, Florian Falter
Publikováno v:
The Journal of Applied Laboratory Medicine. 4:468-470
To the Editor: Activated clotting time (ACT) is used to monitor unfractionated heparin anticoagulation during invasive procedures such as percutaneous coronary or electrophysiology interventions. There are several point-of-care (POC) methods availabl
Autor:
Mark W.M. Schellings, Nicole Bitsch, Johan W. Verjans, Anna Papageorgiou, Stephane Heymans, Paolo Carai, Marieke Rienks, Ilona Cuijpers, Maarten Vanhaverbeke
Publikováno v:
Basic Research in Cardiology
Basic Research in Cardiology, 112(4):42. Springer
Basic Research in Cardiology, 112(4):42. Springer
Optimal healing after myocardial infarction requires not only the induction of inflammation, but also its timely resolution. In patients, 30 days post myocardial infarction, circulating monocytes have increased expression of Semaphorin3A (Sema3A) as
Autor:
Marc A. M. J. van Zandvoort, Melissa Swinnen, Geert C. van Almen, Casper Eurlings, Jack P.M. Cleutjens, Mark W.M. Schellings, Rick van Leeuwen, Wouter Verhesen, Blanche Schroen, Mathijs van de Vrie, Stephane Heymans
Publikováno v:
Aging Cell. 10:769-779
To understand the process of cardiac aging, it is of crucial importance to gain insight into the age-related changes in gene expression in the senescent failing heart. Age-related cardiac remodeling is known to be accompanied by changes in extracellu
Autor:
Paul Gordon, Sander L Wolters, Michelle Lax, Hendrikus H. Boersma, Jaap Teule, Simon Schalla, Mark W.M. Schellings, Jagat Narula, Johan W. Verjans, Gerrit J. Kemerink, Ward Laufer, Dagfinn Lovhaug, L. Hofstra
Publikováno v:
Journal of Nuclear Cardiology, 17(6), 1065-1072. Springer
Journal of Nuclear Cardiology
Journal of Nuclear Cardiology
Introduction The clinical feasibility of noninvasive imaging of interstitial alterations after myocardial infarction (MI) was assessed using a technetium-99m-labeled RGD imaging peptide (RIP). In experimental studies, RIP has been shown to target int
Autor:
Marja P. van Dieijen-Visser, Jagat Narula, Mark H.M. Winkens, Alma M.A. Mingels, Ivo A. Joosen, Joachim E. Wildberger, Eduard M. Laufer, Mark W.M. Schellings, Tim Leiner, Leonard Hofstra
Publikováno v:
Arteriosclerosis Thrombosis and Vascular Biology, 30(6), 1269-1275. LIPPINCOTT WILLIAMS & WILKINS
Objective— This study explored the relationship between coronary atherosclerotic plaque burden and quantifiable circulating levels of troponin measured with a recently introduced high sensitive cardiac troponin T (hs-cTnT) assay. Methods and Result
Publikováno v:
Journal of Cell Communication and Signaling
Cardiac remodeling after myocardial injury involves inflammation, angiogenesis, left ventricular hypertrophy and matrix remodeling. Thrombospondins (TSPs) belong to the group of matricellular proteins, which are non-structural extracellular matrix pr
Autor:
Jos G. Maessen, Ingeborg van der Made, Stephane Heymans, Viola Lentink, Paul Barenbrug, Anke J. Tijsen, Rick van Leeuwen, Joost J. Leenders, Yigal M. Pinto, Blanche Schroen, Mark W.M. Schellings, Veronica Herias, Esther E. Creemers, Rudy F. J. J. Duisters
Publikováno v:
Circulation research, 104(2), 170-U61. Lippincott Williams and Wilkins
The myocardium of the failing heart undergoes a number of structural alterations, most notably hypertrophy of cardiac myocytes and an increase in extracellular matrix proteins, often seen as primary fibrosis. Connective tissue growth factor (CTGF) is
Autor:
Frans Van de Werf, Peter Carmeliet, Melissa Swinnen, Stephane Heymans, E. Helene Sage, Jan D'hooge, Jack P.M. Cleutjens, Yigal M. Pinto, Rick van Leeuwen, Jacques Debets, Mark W.M. Schellings, Davy Vanhoutte
Publikováno v:
Journal of experimental medicine, 206(1), 113-123. Rockefeller University Press
The Journal of Experimental Medicine
The Journal of Experimental Medicine
The matricellular protein SPARC (secreted protein, acidic and rich in cysteine, also known as osteonectin) mediates cell-matrix interactions during wound healing and regulates the production and/or assembly of the extracellular matrix (ECM). This stu
Autor:
Mark W.M. Schellings, Maikel P. Peppelenbosch, Gerjan Navis, Juliane Bolbrinker, Martin H. de Borst, Reinhold Kreutz, Mario B. A. van Dalen, Harry van Goor, Yigal M. Pinto, Sander H. Diks
Publikováno v:
American journal of physiology-Renal physiology, 293(1), F428-F437. AMER PHYSIOLOGICAL SOC
American journal of physiology. Renal physiology, 293(1), F428-F437. American Physiological Society
American journal of physiology. Renal physiology, 293(1), F428-F437. American Physiological Society
Regulation of protein kinase activities is crucial in both physiology and disease, but analysis is hampered by the multitude and complexity of kinase networks. We used novel peptide array chips containing 1,152 known kinase substrate sequences to pro
Autor:
Morten A. Høydal, Michael Schwake, Jacques Debets, Rudy F. J. J. Duisters, Nard Kubben, Ben J. A. Janssen, Mark W.M. Schellings, Stephane Heymans, Mirjam van Loon, Blanche Schroen, Rick van Leeuwen, Anne Bertrand, Yigal M. Pinto, Joost J. Leenders, Paul Saftig, Arie van Erk
Publikováno v:
Journal of experimental medicine, 204(5), 1227-1235. Rockefeller University Press
The Journal of Experimental Medicine
The Journal of Experimental Medicine
The intercalated disc (ID) of cardiac myocytes is emerging as a crucial structure in the heart. Loss of ID proteins like N-cadherin causes lethal cardiac abnormalities, and mutations in ID proteins cause human cardiomyopathy. A comprehensive screen f