Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Mark W. Sims"'
Autor:
Sean Brennan, Simona Esposito, Muhammad I. M. Abdelaziz, Christopher A. Martin, Samir Makwana, Mark W. Sims, Iain B. Squire, Parveen Sharma, Amy E. Chadwick, Richard D. Rainbow
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
Hyperglycaemia at the time of myocardial infarction has an adverse effect on prognosis irrespective of a prior diagnosis of diabetes, suggesting glucose is the damaging factor. In ex vivo models of ischaemia, we demonstrated that deleterious effects
Externí odkaz:
https://doaj.org/article/61cc3fe6d8c84613ac2712b76fa236b6
Autor:
Richard D. Rainbow, Shen Chen, Sean Brennan, Asma S.A. Alonazi, Iain B. Squire, Christopher A Martin, Mark W Sims, Samir Makwana, Jonathan M. Willets
Publikováno v:
JOURNAL OF PHYSIOLOGY-LONDON
Key points Acute hyperglycaemia at the time of a heart attack worsens the outcome for the patient. Acute hyperglycaemia is not limited to diabetic patients and can be due to a stress response in non-diabetics. This study suggests that the damaging ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98362b706661f2daa176c94e2b9ff3ca
https://doi.org/10.1113/jp278332
https://doi.org/10.1113/jp278332
Autor:
Robert I. Norman, G. André Ng, Sean Brennan, James Winter, Richard D. Rainbow, Mark W Sims, Iain B. Squire
Publikováno v:
American journal of physiology. Heart and circulatory physiology. 307(4)
While it is well established that mortality risk after myocardial infarction (MI) increases in proportion to blood glucose concentration at the time of admission, it is unclear whether there is a direct, causal relationship. We investigated potential
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd18479d01153f1bf1a051db2f3a5bef
https://pubmed.ncbi.nlm.nih.gov/24951755
https://pubmed.ncbi.nlm.nih.gov/24951755
Autor:
Robert I. Norman, Mark W Sims, Robert Jackson, Manish Patel, David Lodwick, Diane Hudman, Sean Brennan, Richard D. Rainbow
Publikováno v:
Journal of molecular and cellular cardiology. 79
ATP-sensitive potassium (KATP) channels are abundantly expressed in the myocardium. Although a definitive role for the channel remains elusive they have been implicated in the phenomenon of cardioprotection, but the precise mechanism is unclear. We s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18bf4836a67fab5b59c48b1bdbe2c8ba
https://pubmed.ncbi.nlm.nih.gov/25450614
https://pubmed.ncbi.nlm.nih.gov/25450614