Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Mark W. Roy"'
Publikováno v:
Journal of Neurosurgery. 62:874-881
✓ Focal cerebral ischemia initiates multiple detrimental effects in the brain. Chief among these are the regional development of ischemic edema, decreased local perfusion, altered neuronal function, and eventual infarction. To determine if pretreat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e5785f1d9fd0f58d68d3e8b03cbdcdc
https://doi.org/10.3171/jns.1985.62.6.0874
https://doi.org/10.3171/jns.1985.62.6.0874
Publikováno v:
Stroke. 14:765-768
To study the effect of non-hypotensive hemorrhage on cerebral blood flow in normo- and hypertensive states, chloralose anesthetized cats were subjected to graded blood loss (5 ml/kg) every 30 min. Cerebral blood flow was measured using radiolabelled
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0b5c3049786ef9664436100ce8a2033
https://doi.org/10.1161/01.str.14.5.765
https://doi.org/10.1161/01.str.14.5.765
Publikováno v:
Journal of Neurosurgery. 62:269-275
✓ Somatosensory evoked potentials (SEP's) reflect the integrity of the central neuronal pathway, and as such may be used to assess function that remains during a variety of cerebral insults. To evaluate the natural history and utility of SEP's duri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3da5d95ae961d0e1af266cd1366abe0b
https://doi.org/10.3171/jns.1985.62.2.0269
https://doi.org/10.3171/jns.1985.62.2.0269
Publikováno v:
Neurological Research. 8:53-56
This study examined the changes in cerebral blood flow, water content, and lipoxygenase metabolites (leukotrienes) following bilateral carotid artery occlusion (BCO) and reperfusion in the gerbil. The effect of inhibiting lipoxygenase with nordihydro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9a810a546b9e81efde0d359d10a4366
https://doi.org/10.1080/01616412.1986.11739731
https://doi.org/10.1080/01616412.1986.11739731
Autor:
Robert J. Dempsey, Mary E. Maley, Mark W. Roy, David J. Y. Combs, David E. Cowen, David Donaldson
Publikováno v:
Neurosurgery. 21:177-181
Using the bilateral carotid artery occlusion model of cerebral ischemia in the gerbil, we studied the effect of moderate hypothermia (30 to 31 degrees C) on the postischemic production of prostanoids (cyclooxygenase pathway) and leukotrienes (lipoxyg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e27cc545b1e9b092b01942cc0e263b6
https://doi.org/10.1227/00006123-198708000-00007
https://doi.org/10.1227/00006123-198708000-00007
Autor:
Mark W. Roy, David Donaldson, Kathleen L. Meyer, Robert J. Dempsey, Phillip A. Tibbs, Anne B. Young
Publikováno v:
Journal of Neurosurgery. 63:929-936
✓ To test the effect of verapamil and diltiazem in acute stroke, three groups of mongrel cats of either sex underwent occlusion of the middle cerebral artery (MCA) via a transorbital approach under ketamine anesthesia. The first group served as con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10bf08e3a97504a68dddf6ddc36b358b
https://doi.org/10.3171/jns.1985.63.6.0929
https://doi.org/10.3171/jns.1985.63.6.0929
Publikováno v:
Neurosurgery. 22:317-323
Previous studies have indicated that the regional distribution of the arachidonic acid metabolites around a focal ischemic lesion may be important in the pathogenesis of cerebral ischemia. To determine the functional significance of this regionalizat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d00e3bbd6a3785379979bdf57a7135de
https://doi.org/10.1227/00006123-198802000-00007
https://doi.org/10.1227/00006123-198802000-00007
Publikováno v:
Surgical neurology. 26(3)
The diagnosis of tethered spinal cord syndrome should be considered in young patients with progressive orthopedic deformities, lower extremity weakness, urinary and fecal incontinence, low back pain, or combinations of these symptoms. Myelographic, c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48f657bb9bb5a932e6c6bbeee73017ec
https://pubmed.ncbi.nlm.nih.gov/3738717
https://pubmed.ncbi.nlm.nih.gov/3738717
Publikováno v:
Journal of neurosurgery. 64(1)
✓Vasoactive arachidonic acid metabolites are postulated to play a role in the pathogenesis of cerebral ischemia. In order to characterize the local generation of cyclooxygenase and lipoxygenase metabolites of arachidonic acid in transient ischemia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75ff01a7f9054b98a6d6b87c1a379a1f
https://pubmed.ncbi.nlm.nih.gov/3001248
https://pubmed.ncbi.nlm.nih.gov/3001248
Publikováno v:
Neurosurgery. 17(4)
This study examines the pathophysiology of stroke secondary to focal cerebral ischemia. The interaction of arachidonic acid metabolites and polyamines, a class of ubiquitous ornithine-derived molecules with important membrane effects on edema, Ca++-d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a05e674b9693c1a980eb8ef77b0df8b6
https://pubmed.ncbi.nlm.nih.gov/3864030
https://pubmed.ncbi.nlm.nih.gov/3864030