Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Mark W. Mayhew"'
Autor:
Nicholas E. Sherman, Joy M. Polefrone, Kristina Nelson, J. Thomas Parsons, Donald F. Hunt, Jeffrey Shabanowitz, Erin D. Jeffery, Alan F. Horwitz, Mark W. Mayhew, Stephen J. Pratt, Jay W. Fox
Publikováno v:
Journal of Cell Science. 120:3911-3918
βPIX (PAK1-interacting exchange factor beta, encoded by ARHGEF7 ) and PAK1 (p21 activated kinase) are interacting proteins that form a signaling module that mediates a number of cellular activities pertinent to cell migration ([Kim et al., 2001][1];
Publikováno v:
Journal of Cellular Biochemistry. 83:532-546
Protein kinase C-epsilon coordinately regulates changes in cell growth and shape. Cells overproducing protein kinase C-epsilon spontaneously acquire a polarized morphology and extend long cellular membrane protrusions that are reminiscent of the morp
Autor:
Alan F. Horwitz, Mark W. Mayhew, Jay W. Fox, Donna J. Webb, Mykola Kovalenko, Leanna Whitmore
Publikováno v:
Journal of proteome research. 5(9)
The process of cell motility involves coordinate signaling events among proteins associated in interactive integrin-linked networks. Mass spectrometric analysis of immunoprecipitation-derived protein mixtures have provided efficient means of identify
Autor:
Donna J. Webb, Mark W. Mayhew, Mykola Kovalenko, Melanie J. Schroeder, Erin D. Jeffery, Leanna Whitmore, Jeffrey Shabanowitz, Donald F. Hunt, Alan F. Horwitz
Publikováno v:
Journal of cell science. 119(Pt 14)
Autor:
Vincent Vuaroqueaux, Urs Eppenberger, Jonas Cicenas, Serenella Eppenberger-Castori, Edward Wight, Willy Küng, Mark W. Mayhew, Patrick Urban, Martin Labuhn
Publikováno v:
Breast Cancer Research
Introduction Akt1, Akt2 and Akt3 kinases are downstream components of phosphoinositol 3-kinase derived signals from receptor tyrosine kinases, which influence cell growth, proliferation and survival. Akt2 overexpression and amplification have been de
Autor:
Ginger G. Wescott, Meagan A. McJilton, Souvenir D. Tachado, David M. Terrian, Tonia L. Foreman, Mark W. Mayhew, Crystal D. Goodwin
Publikováno v:
Journal of cellular biochemistry. 85(4)
Protein kinase C epsilon is an oncogenic, actin nucleating protein that coordinately regulates changes in cell growth and shape. Cells constitutively expressing PKCϵ spontaneously acquire a polarized morphology and extend long cellular membrane prot
Publikováno v:
The Journal of biological chemistry. 273(41)
Protein kinase C-epsilon (PKC-epsilon) contains a putative actin binding motif that is unique to this individual member of the PKC gene family. We have used deletion mutagenesis to determine whether this hexapeptide motif is required for the physical
Publikováno v:
The Journal of Cell Biology
Individual isoforms of the protein kinase C (PKC) family of kinases may have assumed distinct responsibilities for the control of complex and diverse cellular functions. In this study, we show that an isoform specific interaction between PKC epsilon