Zobrazeno 1 - 10
of 198
pro vyhledávání: '"Mark W. Logue"'
Autor:
Rajendra A. Morey, Yuanchao Zheng, Henry Bayly, Delin Sun, Melanie E. Garrett, Marianna Gasperi, Adam X. Maihofer, C. Lexi Baird, Katrina L. Grasby, Ashley A. Huggins, Courtney C. Haswell, Paul M. Thompson, Sarah Medland, Daniel E. Gustavson, Matthew S. Panizzon, William S. Kremen, Caroline M. Nievergelt, Allison E. Ashley-Koch, Mark W. Logue
Publikováno v:
Translational Psychiatry, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Genetic contributions to human cortical structure manifest pervasive pleiotropy. This pleiotropy may be harnessed to identify unique genetically-informed parcellations of the cortex that are neurobiologically distinct from functional, cytoar
Externí odkaz:
https://doaj.org/article/c70e4e39177a4a89ac4215e867dc171d
Autor:
Agaz H. Wani, Seyma Katrinli, Xiang Zhao, Nikolaos P. Daskalakis, Anthony S. Zannas, Allison E. Aiello, Dewleen G. Baker, Marco P. Boks, Leslie A. Brick, Chia-Yen Chen, Shareefa Dalvie, Catherine Fortier, Elbert Geuze, Jasmeet P. Hayes, Ronald C. Kessler, Anthony P. King, Nastassja Koen, Israel Liberzon, Adriana Lori, Jurjen J. Luykx, Adam X. Maihofer, William Milberg, Mark W. Miller, Mary S. Mufford, Nicole R. Nugent, Sheila Rauch, Kerry J. Ressler, Victoria B. Risbrough, Bart P. F. Rutten, Dan J. Stein, Murray B. Stein, Robert J. Ursano, Mieke H. Verfaellie, Eric Vermetten, Christiaan H. Vinkers, Erin B. Ware, Derek E. Wildman, Erika J. Wolf, Caroline M. Nievergelt, Mark W. Logue, Alicia K. Smith, Monica Uddin
Publikováno v:
BMC Medical Genomics, Vol 17, Iss 1, Pp 1-14 (2024)
Abstract Background Incorporating genomic data into risk prediction has become an increasingly popular approach for rapid identification of individuals most at risk for complex disorders such as PTSD. Our goal was to develop and validate Methylation
Externí odkaz:
https://doaj.org/article/71292b89b7524386adcc89a2a04c6480
Autor:
Zoe E. Neale, Jennifer R. Fonda, Mark W. Miller, Erika J. Wolf, Rui Zhang, Richard Sherva, Kelly M. Harrington, Victoria Merritt, Matthew S. Panizzon, Richard L. Hauger, J. Michael Gaziano, the VA Million Veteran Program, Mark W. Logue
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-18 (2024)
Abstract Background Posttraumatic stress disorder (PTSD) and traumatic brain injury (TBI) are associated with self-reported problems with cognition as well as risk for Alzheimer’s disease and related dementias (ADRD). Overlapping symptom profiles o
Externí odkaz:
https://doaj.org/article/deba554bad8742d5845318631a672ec6
Publikováno v:
Clinical Epigenetics, Vol 16, Iss 1, Pp 1-13 (2024)
Abstract Background Large-scale cohort and epidemiological studies suggest that PTSD confers risk for dementia in later life but the biological mechanisms underlying this association remain unknown. This study examined this question by assessing the
Externí odkaz:
https://doaj.org/article/9151a3a18aa041a7a311fdf3ba5f8463
Autor:
Yuanchao Zheng, Kathryn L. Lunetta, Chunyu Liu, Alicia K. Smith, Richard Sherva, Mark W. Miller, Mark W. Logue
Publikováno v:
Epigenetics, Vol 18, Iss 1 (2023)
Differentially methylated regions (DMRs) are genomic regions with methylation patterns across multiple CpG sites that are associated with a phenotype. In this study, we proposed a Principal Component (PC) based DMR analysis method for use with data g
Externí odkaz:
https://doaj.org/article/79108c71b1944b7a825327c3f3d669b0
Autor:
Yuanchao Zheng, Kathryn L. Lunetta, Chunyu Liu, Seyma Katrinli, Alicia K. Smith, Mark W. Miller, Mark W. Logue
Publikováno v:
Epigenetics, Vol 17, Iss 13, Pp 2241-2258 (2022)
Differentially methylated regions (DMRs) are genomic regions with specific methylation patterns across multiple loci that are associated with a phenotype. We examined the genome-wide false positive (GFP) rates of five widely used DMR methods: comb-p,
Externí odkaz:
https://doaj.org/article/de7ccd68e6b2498b86c56589cbf4c5b3
Autor:
Sheila T. Nagamatsu, Gregory Rompala, Yasmin L. Hurd, Diana L. Núñez-Rios, Janitza L. Montalvo-Ortiz, Traumatic Stress Brain Research Group, Victor E. Alvarez, David Benedek, Alicia Che, Dianne A. Cruz, David A. Davis, Matthew J. Girgenti, Ellen Hoffman, Paul E. Holtzheimer, Bertrand R. Huber, Alfred Kaye, John H. Krystal, Adam T. Labadorf, Terence M. Keane, Mark W. Logue, Ann McKee, Brian Marx, Deborah Mash, Mark W. Miller, Crystal Noller, JM-O, William K. Scott, Paula Schnurr, Thor Stein, Robert Ursano, Douglas E. Williamson, Erika J. Wolf, Keith A. Young
Publikováno v:
Frontiers in Psychiatry, Vol 13 (2023)
IntroductionDNA methylation (DNAm), an epigenetic mechanism, has been associated with opioid use disorder (OUD) in preclinical and human studies. However, most of the studies have focused on DNAm at CpG sites. DNAm at non-CpG sites (mCpHs, where H in
Externí odkaz:
https://doaj.org/article/8e534560e2b9492589d5919efc931441
Autor:
Yuanchao Zheng, Melanie E. Garrett, Delin Sun, Emily K. Clarke-Rubright, Courtney C. Haswell, Adam X. Maihofer, Jeremy A. Elman, Carol E. Franz, Michael J. Lyons, William S. Kremen, Matthew Peverill, Kelly Sambrook, Katie A. McLaughlin, Nicholas D. Davenport, Seth Disner, Scott R. Sponheim, Elpiniki Andrew, Mayuresh Korgaonkar, Richard Bryant, Tim Varkevisser, Elbert Geuze, Jonathan Coleman, Jean C. Beckham, Nathan A. Kimbrel, Danielle Sullivan, Mark Miller, Jasmeet Hayes, Mieke Verfaellie, Erika Wolf, David Salat, Jeffrey M. Spielberg, William Milberg, Regina McGlinchey, Emily L. Dennis, Paul M. Thompson, Sarah Medland, Neda Jahanshad, Caroline M. Nievergelt, Allison E. Ashley-Koch, Mark W. Logue, Rajendra A. Morey
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract The volume of subcortical structures represents a reliable, quantitative, and objective phenotype that captures genetic effects, environmental effects such as trauma, and disease effects such as posttraumatic stress disorder (PTSD). Trauma a
Externí odkaz:
https://doaj.org/article/d9472f58cb5e461b8fedf366623c17c9
Autor:
Nathan A. Gillespie, Sean N. Hatton, Donald J. Hagler, Anders M. Dale, Jeremy A. Elman, Linda K. McEvoy, Lisa T. Eyler, Christine Fennema-Notestine, Mark W. Logue, Ruth E. McKenzie, Olivia K. Puckett, Xin M. Tu, Nathan Whitsel, Hong Xian, Chandra A. Reynolds, Matthew S. Panizzon, Michael J. Lyons, Michael C. Neale, William S. Kremen, Carol Franz
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
Magnetic resonance imaging data are being used in statistical models to predicted brain ageing (PBA) and as biomarkers for neurodegenerative diseases such as Alzheimer’s Disease. Despite their increasing application, the genetic and environmental e
Externí odkaz:
https://doaj.org/article/c4ea124e5d2448f795e1f2eec8e76a19
Autor:
Alicia K. Smith, Andrew Ratanatharathorn, Adam X. Maihofer, Robert K. Naviaux, Allison E. Aiello, Ananda B. Amstadter, Allison E. Ashley-Koch, Dewleen G. Baker, Jean C. Beckham, Marco P. Boks, Evelyn Bromet, Michelle Dennis, Sandro Galea, Melanie E. Garrett, Elbert Geuze, Guia Guffanti, Michael A. Hauser, Seyma Katrinli, Varun Kilaru, Ronald C. Kessler, Nathan A. Kimbrel, Karestan C. Koenen, Pei-Fen Kuan, Kefeng Li, Mark W. Logue, Adriana Lori, Benjamin J. Luft, Mark W. Miller, Jane C. Naviaux, Nicole R. Nugent, Xuejun Qin, Kerry J. Ressler, Victoria B. Risbrough, Bart P. F. Rutten, Murray B. Stein, Robert J. Ursano, Eric Vermetten, Christiaan H. Vinkers, Lin Wang, Nagy A. Youssef, INTRuST Clinical Consortium, VA Mid-Atlantic MIRECC Workgroup, PGC PTSD Epigenetics Workgroup, Monica Uddin, Caroline M. Nievergelt
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
PTSD has been associated with DNA methylation of specific loci in the genome, but studies have been limited by small sample sizes. Here, the authors perform a meta-analysis of DNA methylation data from 10 different cohorts and identify CpGs in AHRR t
Externí odkaz:
https://doaj.org/article/cd666af7ab5b48228df77dcce964a1fd