Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Mark W. Leonard"'
Autor:
Janette Sutton, Yajin Ni, Mark W. Leonard, Barbra Sasu, Julien Valton, Dominic Justewicz, Cesar Sommer, Jonathan R. Heyen, Trevor Bentley, Julianne Smith, Thomas Van Blarcom
Publikováno v:
Clinical Lymphoma Myeloma and Leukemia. 19:e24
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf585a3ca4b91928c9d931a149aba59a
https://doi.org/10.1016/j.clml.2019.09.035
https://doi.org/10.1016/j.clml.2019.09.035
Autor:
Julien Valton, Trevor Bentley, Javier Chaparro-Riggers, Julianne Smith, Roman Galetto, Thomas Van Blarcom, Cesar Sommer, Janette Sutton, Bijan Boldajipour, Yajin Ni, Mark W. Leonard, Barbra Sasu
Publikováno v:
Blood. 132:591-591
Autologous chimeric antigen receptor (CAR) T cells targeting B-Cell Maturation Antigen (BCMA) have demonstrated promising clinical activity, inducing durable responses in patients with relapsed/refractory multiple myeloma (MM). Development of autolog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fdd8547e6a93baf2b51882f793e55007
https://doi.org/10.1182/blood-2018-99-119227
https://doi.org/10.1182/blood-2018-99-119227
Autor:
James Douglas Engel, Jon M. Kornhauser, Mark W. Leonard, Kelly E. Mayo, Masayuki Yamamoto, Jennifer H. LaVail
Publikováno v:
Molecular Brain Research. 23:100-110
The molecular mechanisms specifying patterns of gene expression in the vertebrate brain, which in turn determine the developmental fates of specific neurons, are yet to be clearly defined. Individual members of a recently identified family of transcr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c7182c56a308748a14b7e49f26b708b
https://doi.org/10.1016/0169-328x(94)90216-x
https://doi.org/10.1016/0169-328x(94)90216-x
Autor:
I. Chardon-Loriaux, T. Maniatis, Ted Abel, Robert A. Holmgren, A.M. Michelson, J. Winick, James Douglas Engel, Mark W. Leonard
Publikováno v:
Scopus-Elsevier
The GATA transcription factors are a family of C4 zinc finger-motif DNA-binding proteins that play defined roles in hematopoiesis as well as presumptive roles in other tissues where they are expressed (e.g., testis, neuronal and placental trophoblast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df7aa1a90912bb4df01662bb07cbb48f
https://doi.org/10.1242/dev.119.4.1055
https://doi.org/10.1242/dev.119.4.1055
Publikováno v:
Trends in Genetics. 9:380-385
Sequential use of reverse transcriptase and the polymerase chain reaction (RT-PCR) permits rapid and sensitive detection of specific RNAs. However, the greatest advantage of RT-PCR, its remarkable sensitivity, has also limited its usefulness in quant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d88b440731e4ab6dbf184536738d2767
https://doi.org/10.1016/0168-9525(93)90137-7
https://doi.org/10.1016/0168-9525(93)90137-7
Publikováno v:
Blood. 82:1071-1079
Although the formation of terminally differentiated erythroid cells has been shown to require the presence of a functional GATA-1 gene in vivo, the role of this transcription factor and other members of the GATA family at earlier stages of erythroid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::230378bfa82ee925d6efeed327338f9a
https://doi.org/10.1182/blood.v82.4.1071.1071
https://doi.org/10.1182/blood.v82.4.1071.1071
Autor:
Mark W. Leonard, Linda J. Ko, Masayuki Yamamoto, James Douglas Engel, Paul Ting, Kathleen M. George
Publikováno v:
Molecular and Cellular Biology. 11:2778-2784
A family of transcriptional activators has recently been identified in chickens; these transcriptional activators recognize a common consensus motif (WGATAR) through a conserved C4 zinc finger DNA-binding domain. One of the members of this multigene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::25d55ef947c4f611b1dfdc9d20a61bec
https://doi.org/10.1128/mcb.11.5.2778
https://doi.org/10.1128/mcb.11.5.2778
Autor:
James Douglas Engel, Mark W. Leonard, Stuart H. Orkin, Masayuki Yamamoto, Linda J. Ko, Hartmut Beug
Publikováno v:
Genes & Development. 4:1650-1662
NF-E1, a DNA-binding protein that recognizes the general consensus motif WGATAR, is the first tissue-specific factor to be identified in erythroid cells. Using a probe from the murine GF-1 (NF-E1) cDNA clone, we isolated three homologous chicken cDNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::886f55bc814d9242dea10fc62662185c
https://doi.org/10.1101/gad.4.10.1650
https://doi.org/10.1101/gad.4.10.1650
Autor:
Mark W. Leonard, Roger K. Patient
Primer extension is a relatively quick and convenient means by which transcription from a gene transfected into tissue-culture cells can be monitored. The technique can be used to accurately determine the site of transcription initiation or to quanti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::451d64c6e3310de0e5225c6bf8fae750
https://doi.org/10.1385/0-89603-178-0:297
https://doi.org/10.1385/0-89603-178-0:297
