Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Mark W. LaMere"'
Autor:
Hiroki Kawano, Yuko Kawano, Chen Yu, Mark W. LaMere, Matthew J. McArthur, Michael W. Becker, Scott W. Ballinger, Satoshi Gojo, Roman A. Eliseev, Laura M. Calvi
Publikováno v:
Cells, Vol 12, Iss 11, p 1473 (2023)
Mitochondrial dysfunction is observed in various conditions, from metabolic syndromes to mitochondrial diseases. Moreover, mitochondrial DNA (mtDNA) transfer is an emerging mechanism that enables the restoration of mitochondrial function in damaged c
Externí odkaz:
https://doaj.org/article/37aa5e634594414a9d48991551dc5df4
Autor:
Yuko Kawano, Hiroki Kawano, Dalia Ghoneim, Thomas J. Fountaine, Daniel K Byun, Mark W. LaMere, Jason H. Mendler, Tzu-Chieh Ho, Noah A. Salama, Benjamin J. Frisch, Jason R. Myers, Siba El Hussein, John M. Ashton, Mitra Azadniv, Jane L. Liesveld, Youmna Kfoury, David T. Scadden, Michael W. Becker, Laura M. Calvi
SUMMARYMesenchymal stem/stromal cells (MSCs) within the bone marrow microenvironment (BMME) support normal hematopoietic stem and progenitor cells (HSPCs). However, the heterogeneity of human MSCs has limited the understanding of their contribution t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1620cde45bc77078164157cecacc53e6
https://doi.org/10.1101/2023.04.09.536176
https://doi.org/10.1101/2023.04.09.536176
Autor:
Jozal W. Moore, Jason H. Mendler, Kah Poh (melissa) Loh, Mitra Azadniv, Kristen M. O'Dwyer, Eric J. Huselton, Frank Akwaa, Benjamin J. Frisch, Myla Strawderman, Mark W. LaMere, Daniel K. Byun, Alyssa C. Jasper, Michael W. Becker, Jane L. Liesveld, Laura M. Calvi
Publikováno v:
Blood. 140:4050-4052
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eca04a50c8b70ecf13a043f3fdaf98cd
https://doi.org/10.1182/blood-2022-159515
https://doi.org/10.1182/blood-2022-159515
Autor:
Hiroki Kawano, Yuko Kawano, Matthew J. McArthur, Laura M. Calvi, Satoshi Gojo, Scott W. Ballinger, Charles O. Smith, Roman A. Eliseev, Mark W. LaMere, Michael W. Becker
Publikováno v:
Blood. 140:4695-4696
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7914697e53f8e6acd000ba24c58a6da7
https://doi.org/10.1182/blood-2022-163318
https://doi.org/10.1182/blood-2022-163318
Autor:
Yuko Kawano, Hiroki Kawano, Daniel K. Byun, Dalia Ghoneim, Thomas J Fountaine, Mark W. LaMere, John M. Ashton, Mitra Azadniv, Jane L. Liesveld, Youmna Kfoury, David T. Scadden, Michael W. Becker, Laura M. Calvi
Publikováno v:
Blood. 140:5772-5773
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d63810e012c44810df94ee09288a53a
https://doi.org/10.1182/blood-2022-170070
https://doi.org/10.1182/blood-2022-170070
Autor:
Michael W. Becker, Yamin Li, Yumei Chen, Qiaobing Xu, Tzu-Chieh Ho, Mark W. LaMere, Kam W. Leong, John M. Ashton, Hae-Won Kim, Haiyan Wang, Hye Sung Kim, Caroline Chen, Jing Gong, Cal D. Palumbo
Publikováno v:
Science Advances
A scaffold-mediated system was developed to enhance the local delivery of Cas9 complexes for targeting leukemia stem cells in AML.
Leukemia stem cells (LSCs) sustain the disease and contribute to relapse in acute myeloid leukemia (AML). Therapie
Leukemia stem cells (LSCs) sustain the disease and contribute to relapse in acute myeloid leukemia (AML). Therapie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0af1e06c6f4919e6da7d7acd07be4579
http://europepmc.org/articles/PMC8133753
http://europepmc.org/articles/PMC8133753
Autor:
Tzu-Chieh Ho, Laura M. Calvi, Michael W. Becker, Yu-Chiao Chiu, Mark W. LaMere, Naxin Guo, Jing Wang, Hiroki Kawano, Nikolay V. Dokholyan, Rakesh K. Singh, Craig T. Jordan
Publikováno v:
Blood. 138:1175-1175
Current treatment options for relapsed acute myeloid leukemia (AML) are limited and ineffective for the majority of patients. In AML, primitive leukemia stem cells (LSCs) and pre-leukemic populations are able to maintain the disease and drive relapse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::62c79702ad0456a662a886eb30845c73
https://doi.org/10.1182/blood-2021-149903
https://doi.org/10.1182/blood-2021-149903
Autor:
Elizabeth A. LaMere, Tzu-Chieh Ho, Laura M. Calvi, Yuko Kawano, Jeevisha Bajaj, Daniel K. Byun, John M. Ashton, Caitlin L. Gordnier, Hiroki Kawano, Benjamin J. Frisch, Michael W. Becker, Jane L. Liesveld, Mark W. LaMere
Publikováno v:
Blood. 138:1510-1510
Myelodysplastic syndromes (MDS) are myeloid neoplasms characterized by bone marrow (BM) failure and associated with aging. We have previously shown that reversal of BM microenvironment (BMME) dysfunction in MDS mitigates MDS associated marrow failure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8fbc74c50cc4d33c7ba5a860c3272722
https://doi.org/10.1182/blood-2021-152885
https://doi.org/10.1182/blood-2021-152885
Autor:
Jaqueline P. Williams, Yuko Kawano, Mark W. LaMere, Nicole D. Paris, Laura M. Calvi, Joe V. Chakkalakal, Hiroki Kawano, Elizabeth A. LaMere, Carl J. Johnston, Benjamin J. Frisch, Daniel K Byun
Publikováno v:
Blood. 138:989-989
Targeted irradiation (TR) is widely used for tumor treatment in the clinic. TR benefits tumor therapy through direct effects as well as poorly understood systemic (abscopal) effects. Recent studies suggest that the systemic innate and acquired immune
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb36150fb7242e4bfcf5ea523d7719df
https://doi.org/10.1182/blood-2021-153222
https://doi.org/10.1182/blood-2021-153222
Autor:
Jane L. Liesveld, Laura M. Calvi, Allison J. Li, Mark W. LaMere, Andrew McDavid, Amanda McCabe, Jason R. Myers, Katherine C. MacNamara, James Palis, Michael W. Becker, Benjamin J. Frisch, Archibald S. Perkins, Jerry Saunders, John M. Ashton, Vyacheslav A. Korshunov, Sarah E. Latchney, Kathleen E. McGrath, Fátima Rivera-Escalera, Corey M. Hoffman, Michael R. Elliott, Julianne N. P. Smith
Publikováno v:
JCI Insight. 4
The bone marrow microenvironment (BMME) contributes to the regulation of hematopoietic stem cell (HSC) function, though its role in age-associated lineage skewing is poorly understood. Here we show that dysfunction of aged marrow macrophages (Mφs) d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15e80cb18df52b11b02cb86e9bf3b2fe
https://doi.org/10.1172/jci.insight.124213
https://doi.org/10.1172/jci.insight.124213