Zobrazeno 1 - 10
of 169
pro vyhledávání: '"Mark W. J. Ferguson"'
Publikováno v:
Dermatology Research and Practice, Vol 2010 (2010)
Many patients are dissatisfied with scars on both visible and non-visible body sites and would value any opportunity to improve or minimise scarring following surgery. Approximately 44 million procedures in the US and 42 million procedures in the EU
Externí odkaz:
https://doaj.org/article/4cbdcaf9cfd84c6583cd3179b266d53f
Autor:
Nick L. Occleston, Anthony D. Metcalfe, Adam Boanas, Nicholas J. Burgoyne, Kerry Nield, Sharon O'Kane, Mark W. J. Ferguson
Publikováno v:
Dermatology Research and Practice, Vol 2010 (2010)
Scarring in the skin after trauma, surgery, burn or sports injury is a major medical problem, often resulting in loss of function, restriction of tissue movement and adverse psychological effects. Whilst various studies have utilised a range of model
Externí odkaz:
https://doaj.org/article/1ebafbed37834d818ab7f8cd7ad54b52
In this field there has been an explosion of information generated by scientific research. One of the beneficiaries of this has been the study of morphology, where new techniques and analyses have led to insights into a wide range of topics. Advances
Autor:
Fiona M. Boissonade, Claire R. Christmas, Adam J. Harding, Mark W. J. Ferguson, Peter P. Robinson, Alison R. Loescher
Publikováno v:
Neuroscience
Highlights • We have visualized and quantified nerve regeneration at an axonal level. • Axons cross the repair site more directly following mannose-6-phosphate treatment. • Mannose-6-phosphate alters axon sprouting just distal to axon entry int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0f6508294449c3a381c5421d10a9194
https://doi.org/10.1016/j.neuroscience.2014.08.034
https://doi.org/10.1016/j.neuroscience.2014.08.034
Autor:
John A Little, Julian Hanak, Rebecca Murdy, Mark W. J. Ferguson, Natalie Cossar, Katherine M. Getliffe
Publikováno v:
Journal of Immunoassay and Immunochemistry. 33:66-81
Juvista™ drug product contains human recombinant active transforming growth factor beta 3 (TGFβ3; avotermin). Juvista is being developed for the prevention and reduction of human scarring. Phase II and III clinical and development batches of Juvis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1106feadb243f070b1563810c63caf40
https://doi.org/10.1080/15321819.2011.600402
https://doi.org/10.1080/15321819.2011.600402
Publikováno v:
Journal of Anatomy. 220:3-12
The MRL/MpJ mouse displays the rare ability amongst mammals to heal injured ear tissue without scarring. Numerous studies have shown that the formation of a blastema-like structure leads to subsequent tissue regeneration in this model, indicating man
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::74dbf504ab548fa9dee76349f39518b6
https://doi.org/10.1111/j.1469-7580.2011.01452.x
https://doi.org/10.1111/j.1469-7580.2011.01452.x
Autor:
Michael T. Longaker, D. Angus McGrouther, V. Leroy Young, Mark W. J. Ferguson, David N. Herndon, Thomas A. Mustoe, James Bush
Publikováno v:
Wound Repair and Regeneration. 19:s32-s37
Cutaneous scarring is an enormous medical problem with approximately 100 million patients acquiring scars each year. Scar prevention/reduction represents a significant, and largely unmet, clinical need. Research into the prophylactic modulation of sc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::adf66032727d94346c3b123918fbc330
https://doi.org/10.1111/j.1524-475x.2010.00607.x
https://doi.org/10.1111/j.1524-475x.2010.00607.x
Autor:
Jim Bush, Sharon O'kane, Mark Cooper, Mark W. J. Ferguson, David Fairlamb, Nick Occleston, Tracey Mason, Hugh G. Laverty
Publikováno v:
Wound Repair and Regeneration. 19:s38-s48
Scarring in the skin following surgery or trauma may be associated with adverse aesthetic, functional, growth and psychological effects, such that both physicians and patients regard it as important to minimize the appearance of scars. The prophylact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::50c6fc49abc489d2cdbd6d32f293882e
https://doi.org/10.1111/j.1524-475x.2011.00711.x
https://doi.org/10.1111/j.1524-475x.2011.00711.x
Autor:
Duncan A. McGrouther, Lisa D. Taylor, Sharon O'kane, James Bush, Anthony D. Metcalfe, Tracey Mason, Karen So, Gaynor Skotny, Mark W. J. Ferguson, Piyush Durani
Publikováno v:
Plastic and Reconstructive Surgery. 128:163-172
BACKGROUND: Skin scarring is associated with psychosocial distress and has a negative effect on quality of life. The transforming growth factor (TGF)-? family of cytokines plays a key role in scarring. TGF-?3 improves scar appearance in a range of ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65e47444f60958276a6c4ce493ca64b3
https://doi.org/10.1097/prs.0b013e318217429b
https://doi.org/10.1097/prs.0b013e318217429b
Autor:
Sharon O'kane, Marianne Ellin, Hugh G. Laverty, Martin F. Gisby, Mark W. J. Ferguson, Panagiotis Madesis, Anil Day, Philip Mellors
Publikováno v:
Plant Biotechnology Journal. 9:618-628
Human transforming growth factor-?3 (TGF?3) is a new therapeutic protein used to reduce scarring during wound healing. The active molecule is a nonglycosylated, homodimer comprised of 13-kDa polypeptide chains linked by disulphide bonds. Expression o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::89c6ae60ced4bd1f78efb8a13bc93823
https://doi.org/10.1111/j.1467-7652.2011.00619.x
https://doi.org/10.1111/j.1467-7652.2011.00619.x