Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Mark W. Head"'
Publikováno v:
Emerging Infectious Diseases, Vol 24, Iss 8, Pp 1482-1489 (2018)
Chronic wasting disease (CWD) is a contagious and fatal neurodegenerative disease and a serious animal health issue for deer and elk in North America. The identification of the first cases of CWD among free-ranging reindeer and moose in Europe brings
Externí odkaz:
https://doaj.org/article/f9d49d0b28bf4454bd6429fc2f9b2a52
Autor:
Jean Y. Douet, Caroline Lacroux, Naima Aron, Mark W. Head, Séverine Lugan, Cécile Tillier, Alvina Huor, Hervé Cassard, Mark Arnold, Vincent Beringue, James W. Ironside, Olivier Andréoletti
Publikováno v:
Emerging Infectious Diseases, Vol 23, Iss 6, Pp 946-956 (2017)
In the United-Kingdom, ≈1 of 2,000 persons could be infected with variant Creutzfeldt-Jakob disease (vCJD). Therefore, risk of transmission of vCJD by medical procedures remains a major concern for public health authorities. In this study, we used
Externí odkaz:
https://doaj.org/article/e83ef8822d664891943c8244271502b6
Autor:
Marcelo A. Barria, Aru Balachandran, Masanori Morita, Tetsuyuki Kitamoto, Rona Barron, Jean Manson, Richard Knight, James W. Ironside, Mark W. Head
Publikováno v:
Emerging Infectious Diseases, Vol 20, Iss 1, Pp 88-97 (2014)
The risks posed to human health by individual animal prion diseases cannot be determined a priori and are difficult to address empirically. The fundamental event in prion disease pathogenesis is thought to be the seeded conversion of normal prion pro
Externí odkaz:
https://doaj.org/article/1b6cc059690f4c69918ffde6ba9c2414
Autor:
Michael Jones, Darren Wight, Rona Barron, Martin Jeffrey, Jean C. Manson, Christopher Prowse, James W. Ironside, Mark W. Head
Publikováno v:
Emerging Infectious Diseases, Vol 15, Iss 12, Pp 2013-2016 (2009)
To assess interspecies barriers to transmission of transmissible spongiform encephalopathies, we investigated the ability of disease-associated prion proteins (PrPd) to initiate conversion of the human normal cellular form of prion protein of the 3 m
Externí odkaz:
https://doaj.org/article/9ab5598c1ac248f2a95b1d743374ca1d
Autor:
Roger A Moore, Mark W Head, James W Ironside, Diane L Ritchie, Gianluigi Zanusso, Young Pyo Choi, Suzette A Priola
Publikováno v:
PLoS Pathogens, Vol 12, Iss 3, p e1005496 (2016)
Externí odkaz:
https://doaj.org/article/4c5d9a3d53a94212a0521d5d7f5f5f15
Autor:
Emmanuelle Uro-Coste, Hervé Cassard, Stéphanie Simon, Séverine Lugan, Jean-Marc Bilheude, Armand Perret-Liaudet, James W Ironside, Stéphane Haik, Christelle Basset-Leobon, Caroline Lacroux, Katell Peoch', Nathalie Streichenberger, Jan Langeveld, Mark W Head, Jacques Grassi, Jean-Jacques Hauw, Francois Schelcher, Marie Bernadette Delisle, Olivier Andréoletti
Publikováno v:
PLoS Pathogens, Vol 4, Iss 3, p e1000029 (2008)
Sporadic Creutzfeldt-Jakob disease (sCJD) cases are currently subclassified according to the methionine/valine polymorphism at codon 129 of the PRNP gene and the proteinase K (PK) digested abnormal prion protein (PrP(res)) identified on Western blott
Externí odkaz:
https://doaj.org/article/b4b622169ff8416bb3e11fae5b8545c4
Publikováno v:
Handbook of clinical neurology. 145
The human prion diseases comprise Creutzfeldt-Jakob disease, variably protease-sensitive prionopathy, Gerstmann-Sträussler-Scheinker disease, fatal familial insomnia, and kuru. Each is a uniformly fatal rare neurodegenerative disease in which confor
Publikováno v:
The Journal of Pathology: Clinical Research
Human prion diseases constitute a group of infectious and invariably fatal neurodegenerative disorders associated with misfolding of the prion protein. Variant Creutzfeldt–Jakob disease (vCJD) is a zoonotic prion disease linked to oral exposure to
Autor:
Zuzana, Krejciova, James, Alibhai, Chen, Zhao, Robert, Krencik, Nina M, Rzechorzek, Erik M, Ullian, Jean, Manson, James W, Ironside, Mark W, Head, Siddharthan, Chandran
Publikováno v:
The Journal of Experimental Medicine
In this issue of JEM, Krejciova et al. report that astrocytes derived from human iPSCs can replicate human CJD prions. These observations provide a new, potentially very valuable model for studying human prions in cellula and for identifying antiprio
Publikováno v:
Neurodegeneration: The Molecular Pathology of Dementia and Movement Disorders. :354-363