Zobrazeno 1 - 6 of 6 pro vyhledávání: '"Mark W. Gramling"'
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Supplementary Figures 1 - 9 from Oncogenic Protein MTBP Interacts with MYC to Promote Tumorigenesis
Autor: Christine M. Eischen, Hua Xiao, Dale S. Haines, Stephen L. Beauparlant, Xi Chen, Maria Pia Arrate, Mark W. Gramling, Brian C. Grieb
PDF file - 687KB, Supplemental Figures S1-S9. S1 shows MTBP induces proliferation. S2 shows peptides in TIP48 and TIP49 identified by mass spectrometry. S3 shows Mtbp increases the pro-proliferative and transforming functions of Myc. S4 shows increas
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c22d6d451b385490656748cb0027e98
https://doi.org/10.1158/0008-5472.22398509
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3
Oncogenic Protein MTBP Interacts with MYC to Promote Tumorigenesis
Autor: Xi Chen, Hua Xiao, Maria Pia Arrate, Brian C. Grieb, Dale S. Haines, Christine M. Eischen, Stephen L. Beauparlant, Mark W. Gramling
Publikováno v: Cancer Research. 74:3591-3602
Despite its involvement in most human cancers, MYC continues to pose a challenge as a readily tractable therapeutic target. Here we identify the MYC transcriptional cofactors TIP48 and TIP49 and MYC as novel binding partners of Mdm2-binding protein (
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1f55eddcc09bf31727630479a9e022a
https://doi.org/10.1158/0008-5472.can-13-2149
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4
Activated protein C enhances cell motility of endothelial cells and MDA-MB-231 breast cancer cells by intracellular signal transduction
Autor: Frank C. Church, Lea M. Beaulieu, Mark W. Gramling
Activated protein C (APC), an anticoagulant serine protease, has been shown to have non-hemostatic functions related to inflammation, cell survival, and cell migration. In this study we investigate the mechanism by which APC promotes angiogenesis and
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::114a13585a8c08be1358061642411f8b
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5
Plasminogen activator inhibitor-1 is an aggregate response factor with pleiotropic effects on cell signaling in vascular disease and the tumor microenvironment
Autor: Frank C. Church, Mark W. Gramling
Publikováno v: Thrombosis research. 125(5)
In hemostasis, the serine protease inhibitor (serpin) plasminogen activator inhibitor-1 (PAI-1) functions to stabilize clots via inhibition of tissue plasminogen activator (tPA) with subsequent inhibition of fibrinolysis. In tissues, PAI-1 functions
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb394270ff6b47cab1b262156e5253ea
https://pubmed.ncbi.nlm.nih.gov/20079523
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