Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Mark W. Burke"'
Autor:
Jessica Raper, Zsofia Kovacs-Balint, Maud Mavigner, Sanjeev Gumber, Mark W. Burke, Jakob Habib, Cameron Mattingly, Damien Fair, Eric Earl, Eric Feczko, Martin Styner, Sherrie M. Jean, Joyce K. Cohen, Mehul S. Suthar, Mar M. Sanchez, Maria C. Alvarado, Ann Chahroudi
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
The consequences of postnatal Zika infection are not fully understood. Here, the authors show that postnatal Zika infection in infant rhesus macaques alters neurodevelopment resulting in social, cognitive and motor impairments, as well as structural
Externí odkaz:
https://doaj.org/article/0283ef9581304bf991d82682d77bd8b7
Publikováno v:
Brain Sciences, Vol 12, Iss 9, p 1117 (2022)
Fetal alcohol spectrum disorder (FASD) is a chronic debilitating condition resulting in behavioral and intellectual impairments and is considered the most prevalent form of preventable mental retardation in the industrialized world. We previously rep
Externí odkaz:
https://doaj.org/article/9505d155bb67401d93095faf41ede378
Autor:
Ana Rodriguez, Karan Chawla, Nsini A. Umoh, Valerie M. Cousins, Assama Ketegou, Madhumati G. Reddy, Mustafa AlRubaiee, Georges E. Haddad, Mark W. Burke
Publikováno v:
Biomolecules, Vol 5, Iss 4, Pp 3193-3203 (2015)
Alcohol abuse causes 79,000 deaths stemming from severe organ damage in the United States every year. Clinical manifestations of long-term alcohol abuse on the cardiac muscle include defective contractility with the development of dilated cardiomyopa
Externí odkaz:
https://doaj.org/article/c1da06bac1f54ac2b025b60471114ffb
Autor:
Thomas J. LaRocca, Perry Altman, Andrew A. Jarrah, Ron Gordon, Edward Wang, Lahouaria Hadri, Mark W. Burke, Georges E. Haddad, Roger J. Hajjar, Sima T. Tarzami
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 9, p 2267 (2019)
Activation of multiple pathways is associated with cardiac hypertrophy and heart failure. We previously published that CXCR4 negatively regulates β-adrenergic receptor (β-AR) signaling and ultimately limits β-adrenergic diastolic (Ca2+) accumulati
Externí odkaz:
https://doaj.org/article/dee0707d8ed745359b59465e7cdeebd6
Publikováno v:
Brain Sciences, Vol 8, Iss 6, p 106 (2018)
In addition to transmitter functions, many neuroamines have trophic or ontogenetic regulatory effects important to both normal and disordered brain development. In previous work (Mejia et al., 2002), we showed that pharmacologically inhibiting monoam
Externí odkaz:
https://doaj.org/article/268852b4249141bcb730e1b118890e50
Publikováno v:
Brain Sciences, Vol 7, Iss 4, p 40 (2017)
The neurological impact of Human Immunodeficiency Virus (HIV) on children includes loss of brain growth, motor abnormalities and cognitive dysfunction. Despite early antiretroviral treatment (ART) intervention to suppress viral load, neurological con
Externí odkaz:
https://doaj.org/article/d15adf607c8141c4833ac7dd57290c2f
Publikováno v:
Brain Sciences, Vol 6, Iss 4, p 52 (2016)
Fetal alcohol exposure (FAE) alters hippocampal cell numbers in rodents and primates, and this may be due, in part, to a reduction in the number or migration of neuronal progenitor cells. The olfactory bulb exhibits substantial postnatal cellular pro
Externí odkaz:
https://doaj.org/article/33b538df9448424799e14f383049b393
Publikováno v:
Neural Plasticity, Vol 2012 (2012)
Behavioural recovery in children who undergo medically required hemispherectomy showcase the remarkable ability of the cerebral cortex to adapt and reorganize following insult early in life. Case study data suggest that lesions sustained early in chi
Externí odkaz:
https://doaj.org/article/8b24a8d27fd7459dac0972c4d0c8271b
Autor:
Brittany Voth, Camryn Parker, Shane Taylor, Koen K. A. Van Rompay, Kristina De Paris, Janiya Brooks, Heather Carryl, Alexandra Haddad, Mark W Burke, Melanie Swang, Norah Algarzae
Publikováno v:
Journal of neurovirology. 27(6)
Pediatric HIV infection remains a global health crisis with an estimated 150,000 new mother-to-child (MTCT) infections each year. Antiretroviral therapy (ART) has improved childhood survival, but only an estimated 53% of children worldwide have acces
Autor:
Damien A. Fair, Ann Chahroudi, Martin Styner, Jakob Habib, Maria C. Alvarado, Eric Earl, Joyce Cohen, Carmen Mattingly, Eric Feczko, Mark W. Burke, Mar M. Sanchez, Mehul S. Suthar, Zsofia Kovacs-Balint, Sherrie Jean, Maud Mavigner, Sanjeev Gumber, Jessica Raper
Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Zika virus (ZIKV) infection has a profound impact on the fetal nervous system. The postnatal period is also a time of rapid brain growth, and it is important to understand the potential neurobehavioral consequences of ZIKV infection during infancy. H