Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Mark W Widder"'
Publikováno v:
PLoS ONE, Vol 17, Iss 9, p e0274011 (2022)
Engineered nanomaterials pose occupational health and environmental concerns as they possess unique physical and chemical properties that can contribute to toxicity. High throughput toxicity screening methods are needed to address the increasing numb
Externí odkaz:
https://doaj.org/article/6755546d60be46df8206fa7db46b2e6a
Autor:
Chance M. Carbaugh, David A. Jackson, Valerie T. Divito, Kyle P. Glover, Mark W. Widder, William H. van der Schalie, Christopher S. Phillips
Publikováno v:
Journal of Applied Toxicology
Zebrafish are an attractive model for chemical screening due to their adaptability to high‐throughput platforms and ability to display complex phenotypes in response to chemical exposure. The photomotor response (PMR) is an established and reproduc
Autor:
Jennifer M. Mobberley, Scott K. Cooley, William H. van der Schalie, Janine R. Hutchison, Richard M. Ozanich, Angela M. Melville, Mark W. Widder, Valerie T. Divito, Linda M. Brennan, Shelby M. Phillips
Publikováno v:
Journal of microbiological methods. 192
Resuscitation and detection of stressed total coliforms in chlorinated water samples is needed to assess and prevent health effects from adverse exposure. In this study, we report that the addition of a growth enhancer mix consisting of trehalose, so
Autor:
Mark W. Widder, Valerie T. Divito, William H. van der Schalie, Linda M. Brennan, Shelby M. Brooks, Janine R. Hutchison, Richard M. Ozanich, Leah Souris
Publikováno v:
Journal of microbiological methods. 163
The U.S. Environmental Protection Agency Alternative Test Procedure protocol outlines a method to produce chlorine-stressed bacteria for water quality testing. Achieving consistent results is challenging due effluent variability. We describe a starti
Publikováno v:
Environmental toxicology and chemistry. 18(10)
This study evaluated the use of Nothobranchius guentheri as a novel organism for rapid acute toxicity screening. A major advantage of the species is that there is no need to maintain a continuous culture to have organisms immediately available for te
Autor:
William H. van der Schalie, Mark W. Widder, Stephen Beaulieu, Eric S. Money, Jennifer Hoponick Redmon, Khara Grieger, Donna Womack
Publikováno v:
Environment Systems and Decisions. 35:42-53
Assessing the health and environmental risks of engineered nanomaterials (ENMs) continues to be a challenging endeavor. Due to extensive challenges related to applying traditional risk assessment frameworks to ENMs, decision making regarding the use
Autor:
Mary E. Schrock, Mark W. Widder, Elizabeth A. Hanft, Ryan R. James, Linda M. Brennan, William H. van der Schalie
Publikováno v:
Journal of Applied Toxicology. 35:701-708
The US Army's need for a reliable and field-portable drinking water toxicity sensor was the catalyst for the development and evaluation of an electric cell-substrate impedance sensing (ECIS) device. Water testing technologies currently available to s
Autor:
Michael K. McAleer, Alex Greis, Michael W. Mayo, Linda M. Brennan, William H. van der Schalie, Mark W. Widder
Publikováno v:
Journal of Visualized Experiments : JoVE
This manuscript describes how to prepare fluidic biochips with Rainbow trout gill epithelial (RTgill-W1) cells for use in a field portable water toxicity sensor. A monolayer of RTgill-W1 cells forms on the sensing electrodes enclosed within the bioch
Publikováno v:
ResearcherID
Rainbow trout gill epithelial cells (RTgill-W1) are used in a cell-based biosensor that can respond within one hour to toxic chemicals that have the potential to contaminate drinking water supplies. RTgill-W1 cells seeded on enclosed fluidic biochips
Autor:
Tommy R. Shedd, Mark W. Widder, William R. Richardson, Yves B. Mikol, William H. van der Schalie
Publikováno v:
Journal - American Water Works Association. 99:107-115
Automated biomonitoring systems provide continuous, real-time monitoring of changes in water quality and can rapidly identify toxicity associated with a wide range of chemical contaminants while increasing public confidence in drinking water quality.