Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Mark W Pellegrino"'
Autor:
Aundrea K. Westfall, Blair W. Perry, Abu H. M. Kamal, Nicole R. Hales, Jarren C. Kay, Madhab Sapkota, Drew R. Schield, Mark W. Pellegrino, Stephen M. Secor, Saiful M. Chowdhury, Todd A. Castoe
Publikováno v:
BMC Genomics, Vol 23, Iss 1, Pp 1-16 (2022)
Abstract Background Snakes exhibit extreme intestinal regeneration following months-long fasts that involves unparalleled increases in metabolism, function, and tissue growth, but the specific molecular control of this process is unknown. Understandi
Externí odkaz:
https://doaj.org/article/4c5439463c8145e1a37473d01a12ebe9
Autor:
Madhab Sapkota, Mohammed Adnan Qureshi, Siraje Arif Mahmud, Yves Balikosa, Charlton Nguyen, Joseph M. Boll, Mark W. Pellegrino
Publikováno v:
Biology Open, Vol 10, Iss 5 (2021)
A dramatic rise of infections with antibiotic-resistant bacterial pathogens continues to challenge the healthcare field due to the lack of effective treatment regimes. As such, there is an urgent need to develop new antimicrobial agents that can comb
Externí odkaz:
https://doaj.org/article/26a48f2413364de59a6527290e720d2f
Autor:
Mustafi Raisa Amin, Siraje Arif Mahmud, Jonathan L Dowgielewicz, Madhab Sapkota, Mark W Pellegrino
Publikováno v:
PLoS Genetics, Vol 16, Iss 12, p e1009234 (2020)
Cells use a variety of mechanisms to maintain optimal mitochondrial function including the mitochondrial unfolded protein response (UPRmt). The UPRmt mitigates mitochondrial dysfunction by differentially regulating mitoprotective gene expression thro
Externí odkaz:
https://doaj.org/article/7aff9c1c96af4144bf4cf7acfff500e8
Publikováno v:
PLoS Pathogens, Vol 16, Iss 9, p e1008918 (2020)
The mitochondrial unfolded protein response (UPRmt) is a stress-activated pathway promoting mitochondrial recovery and defense against infection. In C. elegans, the UPRmt is activated during infection with the pathogen Pseudomonas aeruginosa-but only
Externí odkaz:
https://doaj.org/article/9cacfc778c064e44bb2aaf2e446ecb02
Publikováno v:
Seminars in Cell & Developmental Biology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ca2f7d37a693e8fc88629d293b94c79
https://doi.org/10.1016/j.semcdb.2023.02.002
https://doi.org/10.1016/j.semcdb.2023.02.002
Publikováno v:
FEBS J
Bacterial pathogens employ a variety of tactics to persist in their host and promote infection. Pathogens often target host organelles in order to benefit their survival, either through manipulation or subversion of their function. Mitochondria are r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f2599442a66c93aa639425301898bce
https://doi.org/10.1111/febs.16126
https://doi.org/10.1111/febs.16126
Autor:
Mark W. Pellegrino, Victor C Obuekwe, Daren C. Card, Richard D. Schargel, Hana B Ali, Todd A. Castoe, Katie N. Kang, Blair W. Perry, Madhab Sapkota, Misha I. Kazi, David E. Greenberg, Joseph M. Boll
Publikováno v:
J Antimicrob Chemother
Objectives Metallo-β-lactamases (MBLs) are an emerging class of antimicrobial resistance enzymes that degrade β-lactam antibiotics, including last-resort carbapenems. Infections caused by carbapenemase-producing Enterobacteriaceae (CPE) are increas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::397cbe8ddf8414a154feea2594eba80d
https://doi.org/10.1093/jac/dkaa242
https://doi.org/10.1093/jac/dkaa242
Autor:
Douja, Chamseddine, Siraje A, Mahmud, Aundrea K, Westfall, Todd A, Castoe, Rance E, Berg, Mark W, Pellegrino
Publikováno v:
Cell Reports. 41:111789
Organisms use several strategies to mitigate mitochondrial stress, including the activation of the mitochondrial unfolded protein response (UPR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::460cff537d7315c0fb729e4dd16fcf8c
https://doi.org/10.1016/j.celrep.2022.111789
https://doi.org/10.1016/j.celrep.2022.111789
Autor:
Blair W. Perry, Siddharth S. Gopalan, Giulia I.M. Pasquesi, Drew R. Schield, Aundrea K. Westfall, Cara F. Smith, Ivan Koludarov, Paul T. Chippindale, Mark W. Pellegrino, Edward B. Chuong, Stephen P. Mackessy, Todd A. Castoe
Publikováno v:
Genome research. 32(6)
Understanding how regulatory mechanisms evolve is critical for understanding the processes that give rise to novel phenotypes. Snake venom systems represent a valuable and tractable model for testing hypotheses related to the evolution of novel regul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4fa200501166f1f1fd9f365f03c86a6
https://pubmed.ncbi.nlm.nih.gov/35649579
https://pubmed.ncbi.nlm.nih.gov/35649579
Autor:
Mark W. Pellegrino, Yves Balikosa, Joseph M. Boll, Siraje Arif Mahmud, Mohammed Adnan Qureshi, Charlton Nguyen, Madhab Sapkota
Publikováno v:
Biology Open
article-version (VoR) Version of Record
Biology Open, Vol 10, Iss 5 (2021)
article-version (VoR) Version of Record
Biology Open, Vol 10, Iss 5 (2021)
A dramatic rise of infections with antibiotic-resistant bacterial pathogens continues to challenge the healthcare field due to the lack of effective treatment regimes. As such, there is an urgent need to develop new antimicrobial agents that can comb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67febdfded40ee722e1785484cf6b0c9
https://pubmed.ncbi.nlm.nih.gov/34184732
https://pubmed.ncbi.nlm.nih.gov/34184732