Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Mark W Julian"'
Autor:
Elliott D Crouser, Mark W Julian, Sabahattin Bicer, Vikas Ghai, Taek-Kyun Kim, Lisa A Maier, May Gillespie, Nabeel Y Hamzeh, Kai Wang
Publikováno v:
PLoS ONE, Vol 16, Iss 1, p e0246083 (2021)
ObjectiveCardiac sarcoidosis is difficult to diagnose, often requiring expensive and inconvenient advanced imaging techniques. Circulating exosomes contain genetic material, such as microRNA (miRNA), that are derived from diseased tissues and may ser
Externí odkaz:
https://doaj.org/article/cc457135c480495d84d5d3c1e133072b
Autor:
Mark W Julian, Heather R Strange, Megan N Ballinger, Richard S Hotchkiss, Tracey L Papenfuss, Elliott D Crouser
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0132921 (2015)
Immune suppression during critical illness predisposes to serious infections. We sought to determine the mechanisms regulating tolerance and cross-tolerance to common pro-inflammatory danger signals in a model that recapitulates the intact in vivo im
Externí odkaz:
https://doaj.org/article/c1db22d0bc67456783e4eef94fa7a23f
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e72354 (2013)
Mitochondrial transcription factor A (TFAM) is normally bound to and remains associated with mitochondrial DNA (mtDNA) when released from damaged cells. We hypothesized that TFAM, bound to mtDNA (or equivalent CpG-enriched DNA), amplifies TNFα relea
Externí odkaz:
https://doaj.org/article/ad27c20178be4a48ad3ea13b32b0303b
Autor:
Elliot Offman, Noopur Singh, Mark W. Julian, Landon W. Locke, Sabahattin Bicer, Jonah Mitchell, Thomas Matthews, Kirsten Anderson, Elliott D. Crouser
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Background: Sarcoidosis is a chronic, multisystem inflammatory disorder characterized by non-caseating epithelioid granulomas; infiltration of mononuclear cells; and destruction of microarchitecture in the skin, eye, heart, and central nervous system
Externí odkaz:
https://doaj.org/article/d001686bf0c047ae87991b877123b4e5
Autor:
Gregory J. Eisinger, Wissam Osman, Evan R. Prather, Mark W. Julian, Mikhail A. Gavrilin, Elliott D. Crouser, Mark D. Wewers
Publikováno v:
Critical Care Explorations
OBJECTIVES: Increased monocyte distribution width (MDW) has recently been shown to be a reliable indicator of early sepsis detection. This study therefore sought to determine if inflammasome activation can be linked to monocyte size changes in sepsis
Autor:
Erik Escobedo, Christoph Burkart, Suzanne Paz, Michaela Ferrer, David Siefker, Elliott D. Crouser, Ryan Andrew Adams, Lauren Guy, Leslie A. Nangle, Mark W. Julian, Clara Polizzi
Publikováno v:
Sarcoidosis and other granulomatous ILD / DPLD.
Autor:
Derek C. Angus, Jennifer M. Kleven, Elliott D. Crouser, Keri Bicking, Robert T. Magari, Gabrielle Procopio, Paarth J. Raj, Mark W. Julian, Christopher W. Seymour, Liliana Tejidor, Joseph E. Parrillo, Vincent G. Esguerra, Diana B. Careaga, Octavia M Peck-Palmer
Publikováno v:
Critical Care Medicine
Supplemental Digital Content is available in the text.
Objectives: Most septic patients are initially encountered in the emergency department where sepsis recognition is often delayed, in part due to the lack of effective biomarkers. This study
Objectives: Most septic patients are initially encountered in the emergency department where sepsis recognition is often delayed, in part due to the lack of effective biomarkers. This study
Autor:
Evelyn Guirado Caceres, Larry S. Schlesinger, Elliott D. Crouser, Van T Le, Mark W. Julian, Landon W. Locke, Audrey C. Papp, Wolfgang Sadee, Peter White
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 60:84-95
The mechanisms underlying abnormal granuloma formation in patients with sarcoidosis are complex and remain poorly understood. A novel in vitro human granuloma model was used to determine the molecu...
Autor:
Mandar S. Joshi, Elliott D. Crouser, Mark W. Julian, Brandon L. Schanbacher, John Anthony Bauer
Publikováno v:
Analytical Cellular Pathology, Vol 21, Iss 1, Pp 41-48 (2000)
Primary defects in mitochondrial function have been implicated in over 100 diverse diseases. In situ, mitochondria possess unique and well-defined morphology in normal healthy cells, but diseases linked to defective mitochondrial function are charact
Externí odkaz:
https://doaj.org/article/62faf8b6d57e4d86844f3d4a95ff56af
Autor:
Erinn M. Hade, Christopher Diaz, Rachel M. Smith, Karen Martin, Elliott D. Crouser, Daniel A. Culver, Barbaros S. Erdal, JoAnne Baran, Mark W. Julian
Publikováno v:
Chest
Background Tobacco smoking is associated with a reduced risk of developing sarcoidosis, and we previously reported that nicotine normalizes immune responses to environmental antigens in patients with active pulmonary sarcoidosis. The effects of nicot