Zobrazeno 1 - 10
of 149
pro vyhledávání: '"Mark W, Feinberg"'
Autor:
Furkan Bestepe, Colette Fritsche, Kartik Lakhotiya, Carolyn E. Niosi, George F. Ghanem, Gregory L. Martin, Ruma Pal-Ghosh, Dakota Becker-Greene, James Weston, Ivana Hollan, Ivar Risnes, Stein Erik Rynning, Liv Heidi Solheim, Mark W. Feinberg, Robert M. Blanton, Basak Icli
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 32, Iss , Pp 995-1009 (2023)
Angiogenesis is critical for tissue repair following myocardial infarction (MI), which is exacerbated under insulin resistance or diabetes. MicroRNAs are regulators of angiogenesis. We examined the metabolic regulation of miR-409-3p in post-infarct a
Externí odkaz:
https://doaj.org/article/900c2a0bbc3d4984a95a1425cd183424
Autor:
Xavier P. Fowler, MD, Mark A. Eid, MD, J. Aaron Barnes, MD, Kunal S. Mehta, MD, Reed W. Bratches, MPH, David Hu, BA, Ella Goodney, Mark A. Creager, MD, Mark P. Bonaca, MD, Mark W. Feinberg, MD, Kayla O. Moore, MPH, Barbara Gladders, MS, David G. Armstrong, DPM, MD, PhD, Philip P. Goodney, MD, MS
Publikováno v:
Journal of Vascular Surgery Cases and Innovative Techniques, Vol 8, Iss 4, Pp 877-884 (2022)
Objective: Administrative claims data offer a rich data source for clinical research. However, its application to the study of diabetic lower extremity ulceration is lacking. Our objective was to create a widely applicable framework by which investig
Externí odkaz:
https://doaj.org/article/bbabe7bc32b34dab9db056b0952ff112
Autor:
Ming Zhai, Shiyu Gong, Peipei Luan, Yefei Shi, Wenxin Kou, Yanxi Zeng, Jiayun Shi, Guanye Yu, Jiayun Hou, Qing Yu, Weixia Jian, Jianhui Zhuang, Mark W. Feinberg, Wenhui Peng
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Vascular smooth muscle cells (VSMCs) are known for their fate plasticity in atherosclerosis plaque progression. Here, Zhai et al. show that extracellular traps generated from CD68 + VSMCs adversely contribute to plaque progression and highlight their
Externí odkaz:
https://doaj.org/article/26bc221919dc47f4938e6eb499fea00d
Autor:
Andrea M. Austin, Niveditta Ramkumar, Barbara Gladders, Jonathan A. Barnes, Mark A. Eid, Kayla O. Moore, Mark W. Feinberg, Mark A. Creager, Marc Bonaca, Philip P. Goodney
Publikováno v:
BMC Medical Research Methodology, Vol 22, Iss 1, Pp 1-10 (2022)
Abstract Background This study illustrates the use of logistic regression and machine learning methods, specifically random forest models, in health services research by analyzing outcomes for a cohort of patients with concomitant peripheral artery d
Externí odkaz:
https://doaj.org/article/48631c81ed824144bf4db48f30bb7037
Autor:
Patrick K. T. Shiu, Johanna K. DiStefano, Suresh K. Alahari, Francisco J. Enguita, Mark W. Feinberg, Nikolaos Sideris, Salih Bayraktar, Leandro Castellano, Diana Luna Buitrago, Andrea Caporali, Alessandro Mannucci, Ajay Goel
Publikováno v:
Non-Coding RNA, Vol 9, Iss 6, p 76 (2023)
We are delighted to share with you our thirteenth Journal Club and highlight some of the most interesting papers published recently [...]
Externí odkaz:
https://doaj.org/article/a30d3337d14b40bcb0f4c79a6403740d
Autor:
Henry S. Cheng, Daniel Pérez-Cremades, Rulin Zhuang, Anurag Jamaiyar, Winona Wu, Jingshu Chen, Aspasia Tzani, Lauren Stone, Jorge Plutzky, Terence E. Ryan, Philip P. Goodney, Mark A. Creager, Marc S. Sabatine, Marc P. Bonaca, Mark W. Feinberg
Publikováno v:
JCI Insight, Vol 8, Iss 10 (2023)
Patients with peripheral artery disease (PAD) and diabetes compose a high-risk population for development of critical limb ischemia (CLI) and amputation, although the underlying mechanisms remain poorly understood. Comparison of dysregulated microRNA
Externí odkaz:
https://doaj.org/article/3e5659fa89f24a509170d7bf63c2bd7c
A miRNA/CXCR4 signaling axis impairs monopoiesis and angiogenesis in diabetic critical limb ischemia
Autor:
Henry S. Cheng, Rulin Zhuang, Daniel Pérez-Cremades, Jingshu Chen, Anurag Jamaiyar, Winona Wu, Grasiele Sausen, Aspasia Tzani, Jorge Plutzky, Jorge Henao-Mejia, Philip P. Goodney, Mark A. Creager, Marc S. Sabatine, Marc P. Bonaca, Mark W. Feinberg
Publikováno v:
JCI Insight, Vol 8, Iss 7 (2023)
Patients with peripheral artery disease (PAD) and diabetes have the highest risk of critical limb ischemia (CLI) and amputation, yet the underlying mechanisms remain incompletely understood. MicroRNA (miRNA) sequencing of plasma from diabetic patient
Externí odkaz:
https://doaj.org/article/f2fe1fa1dd814c8fbc8a3dcf4c6f5b75
Autor:
Thao H P Nguyen, Morten Wang Fagerland, Ivana Hollan, Jon Elling Whist, Mark W Feinberg, Stefan Agewall
Publikováno v:
PLoS ONE, Vol 18, Iss 2, p e0281155 (2023)
ObjectiveTo investigate whether high-sensitivity cardiac troponin T (hsTnT) correlates to markers of disease activity in inflammatory arthritis (IA), and whether antirheumatic treatment influences hsTnT levels.MethodsWe assessed 115 patients with act
Externí odkaz:
https://doaj.org/article/c450c24821ef4651811c3aff05b9ef14
Autor:
Sunil K. Saini, Daniel Pérez‐Cremades, Henry S. Cheng, Kate Kosmac, Charlotte A Peterson, Lingyu Li, Lu Tian, Gengfu Dong, Kevin K. Wu, Brian Bouverat, Stephanie E. Wohlgemuth, Terence Ryan, Robert L. Sufit, Luigi Ferrucci, Mary M. McDermott, Christiaan Leeuwenburgh, Mark W. Feinberg
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 21 (2022)
Background Peripheral artery disease (PAD) is associated with gastrocnemius muscle abnormalities. However, the biological pathways associated with gastrocnemius muscle dysfunction and their associations with progression of PAD are largely unknown. Th
Externí odkaz:
https://doaj.org/article/21587088378c47698ffa4d8ba378fcb0
A macrophage-specific lncRNA regulates apoptosis and atherosclerosis by tethering HuR in the nucleus
Autor:
Viorel Simion, Haoyang Zhou, Stefan Haemmig, Jacob B. Pierce, Shanelle Mendes, Yevgenia Tesmenitsky, Daniel Pérez-Cremades, James F. Lee, Alex F. Chen, Nicoletta Ronda, Bianca Papotti, Jarrod A. Marto, Mark W. Feinberg
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Long non coding RNA molecules have been implicated in the immunopathology of a range of inflammatory pathologies. Here the authors show lncRNA MAARS regulates apoptosis via interaction with HuR in the context of atherosclerosis.
Externí odkaz:
https://doaj.org/article/a42036a2b39749688a2059d2a4192cf7