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Publikováno v:
The International Journal of Advanced Manufacturing Technology. 122:773-781
Autor:
Arie P. Otte, Thijs Hendrix, Richard George Antonius Bernardus Sewalt, Dieter Schweizer, Martin Melcher, Monika Lachner, Karien M. Hamer, Mark Vargas, Jan L. den Blaauwen, Thomas Jenuwein
Publikováno v:
Molecular and Cellular Biology. 22:5539-5553
Polycomb group (PcG) proteins form multimeric chromatin-associated protein complexes that are involved in heritable repression of gene activity. Two distinct human PcG complexes have been characterized. The EED/EZH2 PcG complex utilizes histone deace