Zobrazeno 1 - 10 of 30 pro vyhledávání: '"Mark Tristan J. Quimque"'
1
Akademický článek
Anti-HIV reverse transcriptase plant polyphenolic natural products with in silico inhibitory properties on seven non-structural proteins vital in SARS-CoV-2 pathogenesis
Autor: Von Novi O. de Leon, Joe Anthony H. Manzano, Delfin Yñigo H. Pilapil, Rey Arturo T. Fernandez, James Kyle Anthony R. Ching, Mark Tristan J. Quimque, Jay Carl M. Agbay, Kin Israel R. Notarte, Allan Patrick G. Macabeo
Publikováno v: Journal of Genetic Engineering and Biotechnology, Vol 19, Iss 1, Pp 1-17 (2021)
Abstract Background Accessing COVID-19 vaccines is a challenge despite successful clinical trials. This burdens the COVID-19 treatment gap, thereby requiring accelerated discovery of anti-SARS-CoV-2 agents. This study explored the potential of anti-H
Externí odkaz: https://doaj.org/article/f2454d6a821f4faab3437ea280bd59fd
Zobrazit plný text záznamu
2
Akademický článek
Antiproliferative and Cytotoxic Cytochalasins from Sparticola triseptata Inhibit Actin Polymerization and Aggregation
Autor: Katherine Yasmin M. Garcia, Mark Tristan J. Quimque, Christopher Lambert, Katharina Schmidt, Gian Primahana, Theresia E. B. Stradal, Andreas Ratzenböck, Hans-Martin Dahse, Chayanard Phukhamsakda, Marc Stadler, Frank Surup, Allan Patrick G. Macabeo
Publikováno v: Journal of Fungi, Vol 8, Iss 6, p 560 (2022)
Laying the groundwork on preliminary structure–activity relationship study relating to the disruptive activity of cytochalasan derivatives on mammalian cell actin cytoskeleton, we furthered our study on the cytochalasans of the Dothideomycetes fung
Externí odkaz: https://doaj.org/article/943db7be3e504b7c89599f78c1628c9a
Zobrazit plný text záznamu
3
Akademický článek
Enhanced Oral Bioavailability of the Pharmacologically Active Lignin Magnolol via Zr-Based Metal Organic Framework Impregnation
Autor: Joshua H. Santos, Mark Tristan J. Quimque, Allan Patrick G. Macabeo, Mary Jho-Anne T. Corpuz, Yun-Ming Wang, Tsai-Te Lu, Chia-Her Lin, Oliver B. Villaflores
Publikováno v: Pharmaceutics, Vol 12, Iss 5, p 437 (2020)
Bioavailability plays an important role in drug activity in the human body, as certain drug amounts should be present to elicit activity. However, low bioavailability of drugs leads to negligible use for human benefit. In this study, the diversely ac
Externí odkaz: https://doaj.org/article/37fdedb0a3154807a519a0245f4da50b
Zobrazit plný text záznamu
4
Akademický článek
Alpha-Glucosidase- and Lipase-Inhibitory Phenalenones from a New Species of Pseudolophiostoma Originating from Thailand
Autor: Allan Patrick G. Macabeo, Luis Agustin E. Pilapil, Katherine Yasmin M. Garcia, Mark Tristan J. Quimque, Chayanard Phukhamsakda, Allaine Jean C. Cruz, Kevin D. Hyde, Marc Stadler
Publikováno v: Molecules, Vol 25, Iss 4, p 965 (2020)
The alpha-glucosidase- and lipase-inhibitory activities of three phenalenones (1−3) and one phenylpropanoid (4) from the ethyl acetate extracts of a Pseudolophiosptoma sp. are described. They represent the first secondary metabolites reported from
Externí odkaz: https://doaj.org/article/3c10cd631989496ab79911a34e1df81c
Zobrazit plný text záznamu
7
Computational and Experimental Assessments of Magnolol as a Neuroprotective Agent and Utilization of UiO-66(Zr) as Its Drug Delivery System
Autor: Joshua H. Santos, Mark Tristan J. Quimque, Allan Patrick G. Macabeo, Jay Carl M. Agbay, Chia Her Lin, Rhenz Alfred D Liman, Yun-Ming Wang, Oliver B. Villaflores, Mary Jho Anne Corpuz, Tsai-Te Lu
Publikováno v: ACS Omega, Vol 6, Iss 38, Pp 24382-24396 (2021)
ACS Omega
The phenolic natural product magnolol exhibits neuroprotective properties through β-amyloid toxicity in PC-12 cells and ameliorative effects against cognitive deficits in a TgCRND8 transgenic mice model. Its bioavailability and blood–brain barrier
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f443d01ebfb94ce439da107a9645f567
https://doi.org/10.1021/acsomega.1c02555
Zobrazit plný text záznamu
8
Myxobacterial depsipeptide chondramides interrupt SARS-CoV-2 entry by targeting its broad, cell tropic spike protein
Autor: John Jeric San Jose, Rey Arturo T. Fernandez, M. Michael Gromiha, Kin Israel Notarte, Simone Brogi, Allan Patrick G. Macabeo, Omar Villalobos, Nisha Harur Muralidharan, Joe Anthony H. Manzano, Delfin Yñigo H. Pilapil, Mark Tristan J. Quimque, Von Novi de Leon
Publikováno v: Journal of Biomolecular Structure & Dynamics
article-version (VoR) Version of Record
The severity of the COVID-19 pandemic has necessitated the search for drugs against SARS-CoV-2. In this study, we explored via in silico approaches myxobacterial secondary metabolites against various receptor-binding regions of SARS-CoV-2 spike which
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10c699defe0e6483a209a022c6211eb4
https://doi.org/10.1080/07391102.2021.1969281
Zobrazit plný text záznamu
9
Catechol-Bearing Polyketide Derivatives from Sparticola junci
Autor: Allan Patrick G. Macabeo, Marc Stadler, Kevin D. Hyde, Katherine Yasmin M Garcia, Chayanard Phukhamsakda, Mark Tristan J. Quimque
Publikováno v: Journal of Natural Products. 84:2053-2058
Sparticols A (1) and B (2), two catechol-bearing naphthalenedioxy derivatives, were isolated from the submerged culture of the Spanish broom inhabiting Dothideomycetes fungus, Sparticola junci. The structures of 1 and 2 were established by NMR spectr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::80347102308912ed174f7b7f79c0ef69
https://doi.org/10.1021/acs.jnatprod.1c00415
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje