Zobrazeno 1 - 10
of 108
pro vyhledávání: '"Mark Trifiro"'
Publikováno v:
Asian Journal of Andrology, Vol 25, Iss 3, Pp 296-308 (2023)
A complete proteomics study characterizing active androgen receptor (AR) complexes in prostate cancer (PCa) cells identified a diversity of protein interactors with tumorigenic annotations, including known RNA splicing factors. Thus, we chose to furt
Externí odkaz:
https://doaj.org/article/958c44906c11497dbeb30a8d36497c57
Publikováno v:
Diagnostics, Vol 14, Iss 5, p 477 (2024)
The basic principles of ultrafast plasmonic PCR have been promulgated in the scientific and technological literature for over a decade. Yet, its everyday diagnostic utility remains unvalidated in pre-clinical and clinical settings. Although the impre
Externí odkaz:
https://doaj.org/article/038142ebc8844a629284a5758e8440b5
Publikováno v:
Genomics, Proteomics & Bioinformatics, Vol 15, Iss 2, Pp 121-129 (2017)
Mutated genes are rarely common even in the same pathological type between cancer patients and as such, it has been very challenging to interpret genome sequencing data and difficult to predict clinical outcomes. PIK3CA is one of a few genes whose mu
Externí odkaz:
https://doaj.org/article/a4c802a5437c4827af1e839df7b0bc7f
Autor:
Claire Nash, Nadia Boufaied, Dunarel Badescu, Yu Chang Wang, Miltiadis Paliouras, Mark Trifiro, Ioannis Ragoussis, Axel A. Thomson
Publikováno v:
Disease Models & Mechanisms, Vol 12, Iss 7 (2019)
Prostate development is controlled by androgens, the androgen receptor (AR) and mesenchymal–epithelial signalling. We used chromatin immunoprecipitation sequencing (ChIP-seq) to define AR genomic binding in the male and female mesenchyme. Tissue- a
Externí odkaz:
https://doaj.org/article/7e03e3d0d6a242f59b5bd2f9c84c6536
Autor:
Naif Zaman, Lei Li, Maria Luz Jaramillo, Zhanpeng Sun, Chabane Tibiche, Myriam Banville, Catherine Collins, Mark Trifiro, Miltiadis Paliouras, Andre Nantel, Maureen O’Connor-McCourt, Edwin Wang
Publikováno v:
Cell Reports, Vol 5, Iss 1, Pp 216-223 (2013)
Individual cancer cells carry a bewildering number of distinct genomic alterations (e.g., copy number variations and mutations), making it a challenge to uncover genomic-driven mechanisms governing tumorigenesis. Here, we performed exome sequencing o
Externí odkaz:
https://doaj.org/article/c5734c4ca3ab46809467df3d61abd8ef
Autor:
Naif Zaman, Paresa N Giannopoulos, Shafinaz Chowdhury, Eric Bonneil, Pierre Thibault, Edwin Wang, Mark Trifiro, Miltiadis Paliouras
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e113190 (2014)
The androgen receptor (AR) remains an important contributor to the neoplastic evolution of prostate cancer (CaP). CaP progression is linked to several somatic AR mutational changes that endow upon the AR dramatic gain-of-function properties. One of t
Externí odkaz:
https://doaj.org/article/0536eecc0bfe469b90d3e6964b19af80
Publikováno v:
The Analyst. 146:5619-5630
In response to the world's medical community's need for accurate and immediate infectious pathogen detection, many researchers have focused on adapting the standard molecular diagnostic method of polymerase chain reaction (PCR) for point-of-care (POC
Publikováno v:
Plasmonics in Biology and Medicine XIX.
Autor:
Rose Lumbroso, Miltiadis Paliouras, Mark Trifiro, Shafinaz F. Chowdhury, Enrico O. Purisima, Lenore K. Beitel
Publikováno v:
Hormones and Cancer. 10:24-35
The androgen-directed treatment of prostate cancer (PCa) is fraught with the recurrent profile of failed treatment due to drug resistance and must be addressed if we are to provide an effective therapeutic option. The most singular difficulty in the
Publikováno v:
EMBC
A mathematical model for DNA quantification was calibrated using experimental results from real-time 260nm absorption measurements of plasmonic PCR thermocycling. The effect of different PCR parameters on template amplification was investigated using