Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Mark Tomai"'
Autor:
Venkata S. Bollimpelli, Pradeep B. J Reddy, Sailaja Gangadhara, Tysheena P. Charles, Samantha L. Burton, Gregory K. Tharp, Tiffany M. Styles, Celia C. Labranche, Justin C. Smith, Amit A. Upadhyay, Anusmita Sahoo, Traci Legere, Ayalnesh Shiferaw, Vijayakumar Velu, Tianwei Yu, Mark Tomai, John Vasilakos, Sudhir P. Kasturi, George M. Shaw, David Montefiori, Steven E. Bosinger, Pamela A. Kozlowski, Bali Pulendran, Cynthia A. Derdeyn, Eric Hunter, Rama R. Amara
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Route of immunization can markedly influence the quality of immune response. Here, we show that intradermal (ID) but not intramuscular (IM) modified vaccinia Ankara (MVA) vaccinations provide protection from acquisition of intravaginal tier2
Externí odkaz:
https://doaj.org/article/101d7faa095245b791894f88734b70d5
Autor:
Audrey Lee, Madeleine K. D. Scott, Florian Wimmers, Prabhu S. Arunachalam, Wei Luo, Christopher B. Fox, Mark Tomai, Purvesh Khatri, Bali Pulendran
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Adjuvants provide additional impetus for the immune response to vaccination regimens, however their modes of activity and impact on particular compartments of the immune response are currently not well understood. Here the authors perform high resolu
Externí odkaz:
https://doaj.org/article/c4581bcc26564fe192f49148678f0969
Autor:
Nanda Kishore Routhu, Narayanaiah Cheedarla, Venkata Satish Bollimpelli, Sailaja Gangadhara, Venkata Viswanadh Edara, Lilin Lai, Anusmita Sahoo, Ayalnesh Shiferaw, Tiffany M. Styles, Katharine Floyd, Stephanie Fischinger, Caroline Atyeo, Sally A. Shin, Sanjeev Gumber, Shannon Kirejczyk, Kenneth H. Dinnon, Pei-Yong Shi, Vineet D. Menachery, Mark Tomai, Christopher B. Fox, Galit Alter, Thomas H. Vanderford, Lisa Gralinski, Mehul S. Suthar, Rama Rao Amara
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Efficient vaccines for SARS-CoV-2 are needed. Here, the authors show that a trimeric form of the receptor-binding domain of SARS-CoV-2 spike adjuvanted with alum-3M-052 protects non-human primates from disease and inhibits infection.
Externí odkaz:
https://doaj.org/article/eb5e727593c442beadc6bb289092f047
Autor:
K. K. Vidya Vijayan, Kaitlyn A. Cross, Alan D. Curtis, Koen K. A. Van Rompay, Justin Pollara, Christopher B. Fox, Mark Tomai, Tomáš Hanke, Genevieve Fouda, Michael G. Hudgens, Sallie R. Permar, Kristina De Paris
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
A better understanding of the impact of early innate immune responses after vaccine priming on vaccine-elicited adaptive immune responses could inform rational design for effective HIV vaccines. The current study compared the whole blood molecular im
Externí odkaz:
https://doaj.org/article/fba1892012da451aa67da88a57118bb9
Publikováno v:
Infectious Diseases in Obstetrics and Gynecology, Vol 8, Iss 2, Pp 105-111 (2000)
Objectives: Imiquimod (IQ) is used clinically for the topical treatment of external genital warts. IQ is an immune response modifier and induces the expression of interferon-α and other cytokines in human Peripheral Blood Monocytes (PBMC). Trophobla
Externí odkaz:
https://doaj.org/article/985251a05ae1488fac1fa1a94959e47f
Autor:
Waranyoo Phoolcharoen, Balamurugan Shanmugaraj, Narach Khorattanakulchai, Piyanate Sunyakumthorn, Sathit Pichyangkul, Pornnarin Taepavarapruk, Wanlapa Praserthsee, Suchinda Malaivijitnond, Suwimon Manopwisedjaroen, Arunee Thitithanyanont, Kanjana Srisutthisamphan, Anan Jongkaewwattana, Mark Tomai, Christopher B. Fox, Suthira Taychakhoonavudh
Publikováno v:
Vaccine. 41:2781-2792
Autor:
Emma C. Milligan, Katherine Olstad, Caitlin A. Williams, Michael Mallory, Patricio Cano, Kaitlyn A. Cross, Jennifer E. Munt, Carolina Garrido, Lisa Lindesmith, Jennifer Watanabe, Jodie L. Usachenko, Lincoln Hopkins, Ramya Immareddy, Yashavanth Shaan Lakshmanappa, Sonny R. Elizaldi, Jamin W. Roh, Rebecca L. Sammak, Rachel E. Pollard, JoAnn L. Yee, Savannah Herbek, Trevor Scobey, Dieter Miehlke, Genevieve Fouda, Guido Ferrari, Hongmei Gao, Xiaoying Shen, Pamela A. Kozlowski, David Montefiori, Michael G. Hudgens, Darin K. Edwards, Andrea Carfi, Kizzmekia S. Corbett, Barney S. Graham, Christopher B. Fox, Mark Tomai, Smita S. Iyer, Ralph Baric, Rachel Reader, Dirk P. Dittmer, Koen K.A. Van Rompay, Sallie R. Permar, Kristina De Paris
Publikováno v:
Science Translational Medicine. 15
The U.S. Food and Drug Administration only gave emergency use authorization of the BNT162b2 and mRNA-1273 SARS-CoV-2 vaccines for infants 6 months and older in June 2022. Yet questions regarding the durability of vaccine efficacy, especially against
Publikováno v:
Frontiers in Tropical Diseases. 3
Effective and simple delivery of DNA vaccines remains a key to successful clinical applications. Previously, we developed a novel class of DNA vaccines, sometimes called iDNA, which encodes the whole live-attenuated vaccine viruses. Compared to a sta
Autor:
K K Vidya, Vijayan, Kaitlyn A, Cross, Alan D, Curtis, Koen K A, Van Rompay, Justin, Pollara, Christopher B, Fox, Mark, Tomai, Tomáš, Hanke, Genevieve, Fouda, Michael G, Hudgens, Sallie R, Permar, Kristina, De Paris
Systems vaccinology approaches are important tools in rational vaccine design. Our goal was to determine whether early innate immune responses to the vaccine prime in infant rhesus macaques, immunized with two different HIV envelope (Env) vaccine reg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dd4b3c985a5b235ede8421613cc4cfd
Autor:
Madeleine Scott, Audrey Lee, Florian Wimmers, Prabhu Arunachalam, Christopher Fox, Mark Tomai, Purvesh Khatri, Bali Pulendran
Publikováno v:
Journal of Allergy and Clinical Immunology. 149:AB316