Zobrazeno 1 - 10
of 780
pro vyhledávání: '"Mark Thursz"'
Publikováno v:
Journal of Viral Hepatitis. May2014 Supplement, Vol. 21, p1-4. 4p.
Publikováno v:
Journal of viral hepatitis. 21
SUMMARY. Chronic hepatitis C virus (HCV) infection leads to liver fibrosis, cirrhosis and hepatocellular carcinoma (HCC). The recent Global Burden of Disease project estimated that in 2010 among 170 million people living with chronic HCV, an estimate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4374ab8abce7a196ee39b1c7fce180e
https://pubmed.ncbi.nlm.nih.gov/24713003
https://pubmed.ncbi.nlm.nih.gov/24713003
Autor:
Liem B Luong Nguyen, PhD, Maud Lemoine, ProfPhD, Gibril Ndow, MD, Zachary J Ward, PhD, Timothy B Hallet, ProfPhD, Umberto D’Alessandro, ProfPhD, Mark Thursz, ProfMD, Shevanthi Nayagam, PhD, Yusuke Shimakawa, PhD
Publikováno v:
The Lancet Global Health, Vol 12, Iss 1, Pp e66-e78 (2024)
Summary: Background: Global elimination of hepatitis B virus (HBV) requires expanded uptake of antiviral therapy, potentially by simplifying testing algorithms, especially in resource-limited countries. We evaluated the effectiveness, cost-effectiven
Externí odkaz:
https://doaj.org/article/23b74156053c4367a6668b17bbe2e0e4
Autor:
Amina Sow, Maud Lemoine, Papa Souleymane Toure, Madoky Diop, Gora Lo, Jean De Veiga, Omar Thiaw Pape, Khady Seck, Gibril Ndow, Lamin Bojang, Arame Kane, Marina Oudiane, Jess Howell, Shevanthi Nayagam, Jude Moutchia, Isabelle Chemin, Maimuna Mendy, Coumba Toure-Kane, Mark Thursz, Mourtalla Ka, Yusuke Shimakawa, Souleymane Mboup
Publikováno v:
JHEP Reports, Vol 4, Iss 10, Pp 100533- (2022)
Background & Aims: Strategies to implement HBV screening and treatment are critical to achieve HBV elimination but have been inadequately evaluated in sub-Saharan Africa (sSA). Methods: We assessed the feasibility of screen-and-treat interventions in
Externí odkaz:
https://doaj.org/article/2e37f63ee3db4720a20853b951f90100
Autor:
Nikhil Vergis, Rachel Phillips, Victoria Cornelius, Alexia Katsarou, Taryn Youngstein, Lucy Cook, Michelle Willicombe, Clio Pilay, Tina Shturova, Melanie Almonte, Asad Charania, Richard Turner, Onn Min Kon, Graham Cooke, Mark Thursz, Svetlana Cherlin, James Wason, Dragana Milojkovic, Andew J. Innes, Nichola Cooper
Publikováno v:
Trials, Vol 22, Iss 1, Pp 1-4 (2021)
Abstract Objectives The primary objective of MATIS is to determine the efficacy of ruxolitinib (RUX) or fostamatinib (FOS) compared to standard of care (SOC) with respect to reducing the proportion of hospitalised patients progressing from mild or mo
Externí odkaz:
https://doaj.org/article/2df0551e608548efb4436b7a14cb70a7
Autor:
Fanny Lebossé, Cathrin Gudd, Enes Tunc, Arjuna Singanayagam, Rooshi Nathwani, Evangelos Triantafyllou, Oltin Pop, Naveenta Kumar, Sujit Mukherjee, Tie Zheng Hou, Alberto Quaglia, Fabien Zoulim, Julia Wendon, Ameet Dhar, Mark Thursz, Charalambos G. Antoniades, Wafa Khamri
Publikováno v:
EBioMedicine, Vol 49, Iss , Pp 258-268 (2019)
ABSTRACT: Background: Cirrhosis-associated immune dysfunction (CAID) contributes to high sepsis risk in patients with chronic liver disease. Various innate and; to a lesser extent; adaptive immune dysfunctions have been described as contributors to C
Externí odkaz:
https://doaj.org/article/081a539474c34548adf6b8413edd5c2e
Autor:
Alastair Heffernan, Yanling Ma, Shevanthi Nayagam, Polin Chan, Zhongdan Chen, Graham S Cooke, Yan Guo, Chuntao Liu, Mark Thursz, Wanyue Zhang, Xiaobing Zhang, Xiujie Zhang, Manhong Jia, Timothy B Hallett
Publikováno v:
PLoS ONE, Vol 16, Iss 1, p e0245288 (2021)
BackgroundThe paradigm shift in hepatitis C virus (HCV) treatment options in the last five years has raised the prospect of eliminating the disease as a global health threat. This will require a step-change in the number being treated with the new di
Externí odkaz:
https://doaj.org/article/15a72278c63c4fa0b3ed28ee167d6dbf
Autor:
Brian Hanley, MBBCh, Kikkeri N Naresh, ProfMD, Candice Roufosse, PhD, Andrew G Nicholson, ProfDM, Justin Weir, FRCPath, Graham S Cooke, ProfFRCP, Mark Thursz, ProfMD, Pinelopi Manousou, PhD, Richard Corbett, PhD, Robert Goldin, ProfMD, Safa Al-Sarraj, ProfFRCPath, Alireza Abdolrasouli, PhD, Olivia C Swann, MRes, Laury Baillon, BSc, Rebecca Penn, MSc, Wendy S Barclay, ProfPhD, Patrizia Viola, MD, Michael Osborn, FRCPath
Publikováno v:
The Lancet Microbe, Vol 1, Iss 6, Pp e245-e253 (2020)
Summary: Background: Severe COVID-19 has a high mortality rate. Comprehensive pathological descriptions of COVID-19 are scarce and limited in scope. We aimed to describe the histopathological findings and viral tropism in patients who died of severe
Externí odkaz:
https://doaj.org/article/b910c056406e4a2cbe5e3619d204d092
Autor:
Damien Cohen, Sumantra Ghosh, Yusuke Shimakawa, Njie Ramou, Pierre Simon Garcia, Anaëlle Dubois, Clément Guillot, Nora Kakwata-Nkor Deluce, Valentin Tilloy, Geoffroy Durand, Catherine Voegele, Gibril Ndow, Umberto d'Alessandro, Céline Brochier-Armanet, Sophie Alain, Florence Le Calvez-Kelm, Janet Hall, Fabien Zoulim, Maimuna Mendy, Mark Thursz, Maud Lemoine, Isabelle Chemin
Publikováno v:
JHEP Reports, Vol 2, Iss 5, Pp 100144- (2020)
Background & Aims: Although HBV is a major cause of death in Africa, its genetic variability has been poorly documented. This study aimed to address whether HBV genotype and surface gene variants are associated with HBV-related liver disease in The G
Externí odkaz:
https://doaj.org/article/192d73219e2e497587415f6ef2ae2755
Autor:
Shevanthi Nayagam, Elisa Sicuri, Maud Lemoine, Philippa Easterbrook, Lesong Conteh, Timothy B. Hallett, Mark Thursz
Publikováno v:
BMC Infectious Diseases, Vol 17, Iss S1, Pp 107-116 (2017)
Abstract Background Many people living with chronic HBV infection remain undiagnosed until later stages of disease. Increasing testing and treatment rates form part of the strategy to respond to the WHO goal of eliminating viral hepatitis as a public
Externí odkaz:
https://doaj.org/article/d0a9b95e87e34d988332de3a61059b17