Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Mark T. Skoog"'
Autor:
Suresh R. Kapadia, Janice M. Klunder, W. W. Engel, John R. Proudfoot, Guenther Schmidt, S. C. Mauldin, Usha R. Patel, Janice M. Rose, Alan S. Rosenthal, Kollol Pal, K. D. Hargrave, T. D. Saboe, Scot J. Campbell, Jerry W. Skiles, Mark L. Behnke, Mark T. Skoog, Joe C. Wu, W. G. Eberlein, Jana Vitous, Julian Adams, Grace C. Chow, Ernest Cullen, Grozinger Karl G, Victor Fuchs, Mcneil Daniel W
Publikováno v:
ChemInform. 22
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a5c008debc58da9d4d5584d876714947
https://doi.org/10.1002/chin.199152234
https://doi.org/10.1002/chin.199152234
Autor:
Jerry L. Hopskins, Patricia M. Bax, Mark T. Skoog, Michel J. Emmanuel, Cathleen R. Joseph, Kenneth A. Cohen, Peter Pallai, Rajashekhar Betageri
Publikováno v:
Journal of Biochemical and Biophysical Methods. 23:107-113
The 3C protease encoded by human rhinovirus type 2 catalyzes with equal efficiency cleavage of a peptide substrate with or without a fluorescein label attahed to the aminoa cid at the P7′ position. Substrates Ac-MEALFQGPLQYKDL-NH2 and MEALFQGPLQYKE
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5d3e625ac02de01163019693d61a627
https://doi.org/10.1016/0165-022x(91)90058-5
https://doi.org/10.1016/0165-022x(91)90058-5
Autor:
Victor Fuchs, Janice M. Rose, Kollol Pal, Mark L. Behnke, Wolfhard W. Engel, Usha R. Patel, Scot J. Campbell, Suresh R. Kapadia, Julian Adams, Jerry W. Skiles, Joe C. Wu, Gunther Schmidt, Grozinger Karl G, Alan S. Rosenthal, Tracy D. Saboe, Wolfgang G. Eberlein, Jana Vitous, Janice M. Klunder, John R. Proudfoot, Ernest Cullen, Mark T. Skoog, Mcneil Daniel W, Scott C. Mauldin, Grace C. Chow, Karl D. Hargrave
Publikováno v:
Journal of Medicinal Chemistry. 34:2231-2241
Novel pyrido[2,3-b][1,4]benzodiazepinones (I), pyrido[2,3-b][1,5]benzodiazepinones (II), and dipyrido[3,2-b:2',3'-e][1,4]diazepinones (III) were found to inhibit human immunodeficiency virus type 1 (HIV-1) reverse transcriptase in vitro at concentrat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::680f1db75eddd4d131f02bf1a70896f9
https://doi.org/10.1021/jm00111a045
https://doi.org/10.1021/jm00111a045
Autor:
Jerry L. Hopkins, Piet de Dreu, Mark T. Skoog, Kenneth A. Cohen, Michel J. Emmanuel, Grace C. Chow, Diane Thibeault, Rajashekhar Betageri
Publikováno v:
Journal of biochemical and biophysical methods. 27(3)
The proteinase encoded by human immunodeficiency virus type 1 (HIV-1) cleaves peptide substrates of sequences derived from processing sites in HIV-1 gag-pol polypeptide. Based on this cleavage, assays that utilize HPLC to measure activity of HIV-1 pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47611ec21aba6932620145d9b9e38d61
https://pubmed.ncbi.nlm.nih.gov/8258639
https://pubmed.ncbi.nlm.nih.gov/8258639
Publikováno v:
Medicinal research reviews. 12(1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a07ae6b4d9fdb9a10749135adb151d42
https://pubmed.ncbi.nlm.nih.gov/1371177
https://pubmed.ncbi.nlm.nih.gov/1371177
Autor:
Peter M. Grob, Anthony Shrutkowski, John Miglietta, Mark T. Skoog, Elizabeth B. Kopp, Cheng-Kon Shih
Steady state kinetics and inhibition by a dipyridodiazepinone of the reverse transcriptase from human immunodeficiency virus type 1 (HIV) were studied using a heteropolymeric RNA template with a sequence from the authentic initiation site on the HIV
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad8394d81a07f3db529583fced7908ea
https://europepmc.org/articles/PMC328267/
https://europepmc.org/articles/PMC328267/
Autor:
Mark T. Skoog, Larry E. Baugh, Philip M. Weintraub, James S. Nichols, Edward W. Huber, Jeffrey S. Wiseman, Amy M. Farrell
Publikováno v:
ChemInform. 21
A series of substituted 3,4-dihydro-2H-1,4-thiazines inhibit 5-lipoxygenase from rat leukocytes and exhibit submicromolar IC50 values. A novel synthesis of these compounds was developed based on the formation of hydroxymethyleneamine 13 and its cycli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e483c6f5b8dee6e26d5cb8c0e57e42f
https://doi.org/10.1002/chin.199017197
https://doi.org/10.1002/chin.199017197
Autor:
R. J. Eckner, Julian Adams, K. Eckner, Grozinger Karl G, V. J. Merluzzi, R. Faanes, M. Labadia, A.S. Rosenthal, Mark T. Skoog, S. Hattox, Joe C. Wu, R.A. Koup, Cheng-Kon Shih, John L. Sullivan, K. D. Hargrave
Publikováno v:
Antiviral Research. 15:45
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::76f49a0ed81ec7f586582e52a2ea7867
https://doi.org/10.1016/0166-3542(91)90089-a
https://doi.org/10.1016/0166-3542(91)90089-a
Autor:
Philip M. Weintraub, James S. Nichols, Jeffrey S. Wiseman, Mark T. Skoog, Edward W. Huber, Larry E. Baugh, Amy M. Farrell
Publikováno v:
Journal of Pharmaceutical Sciences. 78:937-943
A series of substituted 3,4-dihydro-2H-1,4-thiazines inhibit 5-lipoxygenase from rat leukocytes and exhibit submicromolar IC50 values. A novel synthesis of these compounds was developed based on the formation of hydroxymethyleneamine 13 and its cycli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6f0219fea97bde7700beb40ab02604d
https://doi.org/10.1002/jps.2600781112
https://doi.org/10.1002/jps.2600781112
Autor:
Mark T. Skoog, Eckard Wimmer, Richard H. Ingraham, Carol A. Carter, Hans-Georg Kräusslich, Peter Pallai
Publikováno v:
Proceedings of the National Academy of Sciences. 86:807-811
Retroviral capsid proteins and replication enzymes are synthesized as polyproteins that are proteolytically processed to the mature products by a virus-encoded proteinase. We have purified the proteinase of human immunodeficiency virus (HIV), express
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::160027b67cc4c163420508484f5daf6b
https://doi.org/10.1073/pnas.86.3.807
https://doi.org/10.1073/pnas.86.3.807