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pro vyhledávání: '"Mark T. Kresnak"'
Autor:
Richard L. Davidson, Mark T. Kresnak
Publikováno v:
Somatic Cell and Molecular Genetics. 19:589-598
We have previously demonstrated that mutagenesis by bromodeoxyuridine (BrdU) and thymidine (dT) in mammalian cells occurs with a high degree of sequence specificity within runs of multiple adjacent guanine residues. To determine whether there is a st
Autor:
Mark T. Kresnak, Richard L. Davidson
Publikováno v:
Proceedings of the National Academy of Sciences. 89:2829-2833
Imbalances in the intracellular nucleotide precursor pools in mammalian cells can result in the induction of mutations during the DNA replication process. By using a shuttle vector system developed in our laboratory, we have analyzed the sequence spe
Publikováno v:
Somatic cell and molecular genetics. 18(2)
For studies on molecular mechanisms of mutagenesis, it would be advantageous to transfer mutant genes with specific alterations into mammalian cells and use the transformed cells in reversion analyses. In the present paper, we describe an efficient m
Autor:
Mark T. Kresnak, Richard L. Davidson
Publikováno v:
Somatic cell and molecular genetics. 17(4)
The molecular mechanisms of incorporation-dependent, 5-bromodeoxyuridine (BrdU)-induced mutagenesis were analyzed in murine A9 cells that possess a single copy of the Escherichia coli gpt gene integrated into the chromosomal DNA as part of a shuttle