Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Mark T W Handley"'
Publikováno v:
PLoS ONE, Vol 5, Iss 5, p e10534 (2010)
Neuronal calcium sensor-1 (NCS-1) is a Ca(2+) sensor protein that has been implicated in the regulation of various aspects of neuronal development and neurotransmission. It exerts its effects through interactions with a range of target proteins one o
Externí odkaz:
https://doaj.org/article/220cc48e786c490bbdbb9404cb4b02ee
Autor:
Robert D. Burgoyne, Stephanie L. Barrow, Leo F. Ciufo, Jeff W. Barclay, Margaret E. Graham, Alan Morgan, Mark T. W. Handley
Publikováno v:
Biochemical Journal. 409:407-416
Munc18-1 plays a crucial role in regulated exocytosis in neurons and neuroendocrine cells through modulation of vesicle docking and membrane fusion. The molecular basis for Munc18 function is still unclear, as are the links with Rabs and SNARE [SNAP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6a9ec8f4083649690815e51138f7fe3
https://doi.org/10.1042/bj20071094
https://doi.org/10.1042/bj20071094
Autor:
Alan Morgan, Robert D. Burgoyne, Leo F. Ciufo, Margaret E. Graham, Mark T. W. Handley, Jeff W. Barclay
Publikováno v:
Annals of the New York Academy of Sciences. 1152
The activation of regulated exocytosis occurs by a rise in cytosolic Ca(2+) concentration. Synaptotagmins act as the Ca(2+) sensors, whereas the machinery that allows fusion of secretory vesicles with the plasma membrane consists of the soluble N-eth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e7ae749083cee107b17bc11623444fc
https://pubmed.ncbi.nlm.nih.gov/19161378
https://pubmed.ncbi.nlm.nih.gov/19161378
Autor:
Mark T. W. Handley, Robert D. Burgoyne
Publikováno v:
Biochemical and biophysical research communications. 373(2)
Rab proteins are GTPases that transit between GTP- and GDP-bound states. In the GTP-bound form they can recruit specific effector to membrane domains. It is possible that the exchange of Rab effectors between membranes and cytosol would be determined
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::110308573099ed1ff335ad1dd265f299
https://pubmed.ncbi.nlm.nih.gov/18573236
https://pubmed.ncbi.nlm.nih.gov/18573236
Publikováno v:
PLoS ONE, Vol 5, Iss 5, p e10534 (2010)
PLoS ONE
PLoS ONE
Neuronal calcium sensor-1 (NCS-1) is a Ca(2+) sensor protein that has been implicated in the regulation of various aspects of neuronal development and neurotransmission. It exerts its effects through interactions with a range of target proteins one o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e44169104b7c215aa2c024715b5db8f
https://doi.org/10.1371/journal.pone.0010534
https://doi.org/10.1371/journal.pone.0010534