Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Mark T Romanish"'
Publikováno v:
PLoS Computational Biology, Vol 7, Iss 5, p e1002046 (2011)
Comprising nearly half of the human and mouse genomes, transposable elements (TEs) are found within most genes. Although the vast majority of TEs in introns are fixed in the species and presumably exert no significant effects on the enclosing gene, s
Externí odkaz:
https://doaj.org/article/4dbee1e84501471d9d3066576c52b02c
A novel protein isoform of the multicopy human NAIP gene derives from intragenic Alu SINE promoters.
Publikováno v:
PLoS ONE, Vol 4, Iss 6, p e5761 (2009)
The human neuronal apoptosis inhibitory protein (NAIP) gene is no longer principally considered a member of the Inhibitor of Apoptosis Protein (IAP) family, as its domain structure and functions in innate immunity also warrant inclusion in the Nod-Li
Externí odkaz:
https://doaj.org/article/f336f7a8518e406b99387920378c1ed9
Publikováno v:
PLoS Genetics, Vol 3, Iss 1, p e10 (2007)
Neuronal apoptosis inhibitory protein (NAIP, also known as BIRC1) is a member of the conserved inhibitor of apoptosis protein (IAP) family. Lineage-specific rearrangements and expansions of this locus have yielded different copy numbers among primate
Externí odkaz:
https://doaj.org/article/16f68ef188b84b25bb22b65a538866ec
Autor:
Irina A Maksakova, Mark T Romanish, Liane Gagnier, Catherine A Dunn, Louie N van de Lagemaat, Dixie L Mager
Publikováno v:
PLoS Genetics, Vol 2, Iss 1, p e2 (2006)
The inbred mouse is an invaluable model for human biology and disease. Nevertheless, when considering genetic mechanisms of variation and disease, it is important to appreciate the significant differences in the spectra of spontaneous mutations that
Externí odkaz:
https://doaj.org/article/cdeef4de68c54c20ae0a333ad491349d
Autor:
Mohammad M. Karimi, Liane Gagnier, L Y Kuo, Artem Babaian, Mark T. Romanish, Christian Steidl, Dixie L. Mager
Publikováno v:
Oncogene. 35:2542-2546
The transcription factor interferon regulatory factor 5 (IRF5) is upregulated in Hodgkin lymphoma (HL) and is a key regulator of the aberrant transcriptome characteristic of this disease. Here we show that IRF5 upregulation in HL is driven by transcr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c426208fb77fe758870c5cb4fb1297c5
https://doi.org/10.1038/onc.2015.308
https://doi.org/10.1038/onc.2015.308
Autor:
Cheryl D. Helgason, Hui Xue, Yuwei Wang, Mark T. Romanish, Hisae Nakamura, Yuzhuo Wang, Dixie L. Mager
Publikováno v:
The Prostate. 73:1747-1760
BACKGROUND. Androgen signalling through the androgen receptor (AR) plays a critical role in prostate cancer (PCa) initiation and progression. Estrogen in synergy with androgen is essential for cell growth of the normal and malignant prostate. However
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a26bf98e116b2f86cea0b3cd648a4d43
https://doi.org/10.1002/pros.22712
https://doi.org/10.1002/pros.22712
Publikováno v:
Annual Review of Genetics
Annual Review of Genetics, Annual Reviews, 2012, 46, pp.21-42. ⟨10.1146/annurev-genet-110711-155621⟩
Annual Review of Genetics, Annual Reviews, 2012, 46, pp.21-42. ⟨10.1146/annurev-genet-110711-155621⟩
International audience; The fact that transposable elements (TEs) can influence host gene expression was first recognized more than 50 years ago. However, since that time, TEs have been widely regarded as harmful genetic parasites-selfish elements th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db0a8f6a85f4d6a33c69111c2638f5cb
https://doi.org/10.1146/annurev-genet-110711-155621
https://doi.org/10.1146/annurev-genet-110711-155621
Autor:
Kelly M. McNagny, Fumio Takei, Timotheus Y.F. Halim, Matthew J. Gold, Aric MacLaren, Mark T. Romanish
Publikováno v:
Immunity. 37(3):463-474
Summary Natural helper (NH) cells are innate lymphoid cells (ILCs) that produce T helper-2 (Th2)-cell-type cytokines in the lung- and gut-associated lymphoid tissues. Currently, the lineage relationship between NH cells in different tissues and betwe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12b20308cca7a068e03bfbfbbd8aa679
Autor:
Hisae, Nakamura, Yuwei, Wang, Hui, Xue, Mark T, Romanish, Dixie L, Mager, Cheryl D, Helgason, Yuzhuo, Wang
Publikováno v:
The Prostate. 73(16)
Androgen signalling through the androgen receptor (AR) plays a critical role in prostate cancer (PCa) initiation and progression. Estrogen in synergy with androgen is essential for cell growth of the normal and malignant prostate. However, the exact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::45f88ae0dd8a4736b29cbcaf32779847
https://pubmed.ncbi.nlm.nih.gov/24038102
https://pubmed.ncbi.nlm.nih.gov/24038102
Publikováno v:
Seminars in cancer biology. 20(4)
Malignancy results from a complex combination of genetic and epigenetic changes, the full effects of which are still largely unknown. Here we summarize current knowledge of the origin, retrotranspositional activity, epigenetic state, and transcriptio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be1e8a738b123f75314c2c0b5f8d7fef
https://pubmed.ncbi.nlm.nih.gov/20685251
https://pubmed.ncbi.nlm.nih.gov/20685251