Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Mark T, Worthington"'
Publikováno v:
BioTechniques, Vol 30, Iss 4, Pp 738-742 (2001)
Externí odkaz:
https://doaj.org/article/328fd70e1ff44089bf719029e854983f
Autor:
Thomas W. Sturgill, Carol A. Chrestensen, Andrew Eschenroeder, Jacquelyn K. Shuman, Mark T. Worthington, Hermann Gram
Publikováno v:
Journal of Biological Chemistry. 282:4243-4252
MAPK-interacting protein kinases 1 and 2 (MNK1 and MNK2) function downstream of p38 and ERK MAPK, but there are large gaps in our knowledge of how MNKs are regulated and function. As proteins activated in the HER2/Ras/Raf/ERK pathway, the MNKs are of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::291f63ae114b51e8dedfea96529324a0
https://doi.org/10.1074/jbc.m607368200
https://doi.org/10.1074/jbc.m607368200
Cutting Edge: Critical Role for A2A Adenosine Receptors in the T Cell-Mediated Regulation of Colitis
Autor:
Mark T. Worthington, Joel Linden, Elizabeth B. Wiznerowicz, Makoto Naganuma, Courtney M. Lappas, Peter B. Ernst
Publikováno v:
The Journal of Immunology. 177:2765-2769
A2A adenosine receptors (A2AAR) inhibit inflammation, although the mechanisms through which adenosine exerts its effects remain unclear. Although the transfer of regulatory Th cells blocks colitis induced by pathogenic CD45RBhigh Th cells, we show th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ae5c836f2935f9305cb06ad9609aa89
https://doi.org/10.4049/jimmunol.177.5.2765
https://doi.org/10.4049/jimmunol.177.5.2765
Autor:
Thomas W. Sturgill, Jeffrey Shabanowitz, Melanie J. Schroeder, Carol A. Chrestensen, Mark T. Worthington, Donald F. Hunt, Jared W. Pelo
Publikováno v:
Journal of Biological Chemistry. 279:10176-10184
MAPKAP kinase 2 (MK2) is required for tumor necrosis factor synthesis. Tristetraprolin (TTP) binds to the 3'-untranslated region of tumor necrosis factor mRNA and regulates its fate. We identified in vitro and in vivo phosphorylation sites in TTP usi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9641c38678b72306f46acb02422b3d07
https://doi.org/10.1074/jbc.m310486200
https://doi.org/10.1074/jbc.m310486200
Publikováno v:
Analytical Biochemistry. 294:169-175
Random double-stranded oligonucleotides are useful reagents to identify the optimal binding sites for DNA-binding proteins, such as transcriptional activators. Some applications require ligation of random oligonucleotides to form plasmid-based librar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80c5787d9caa161bd250421e0beb2345
https://doi.org/10.1006/abio.2001.5162
https://doi.org/10.1006/abio.2001.5162
Characterization of a human plasma membrane heme transporter in intestinal and hepatocyte cell lines
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 280:G1172-G1177
Heme is the most bioavailable form of dietary iron and a component of many cellular proteins. Controversy exists as to whether heme uptake occurs via specific transport mechanisms or passive diffusion. The aims of this study were to quantify cellular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50dac6df009fcb0f1623ee34a9030913
https://doi.org/10.1152/ajpgi.2001.280.6.g1172
https://doi.org/10.1152/ajpgi.2001.280.6.g1172
Autor:
Laurie J. Antonik, D. Ronald Goldwater, Keith M. Borkett, Mack C. Mitchell, James P. Lees, Mark T. Worthington, Karin Wilhelm-Ogunbiyi
Publikováno v:
Anesthesia and analgesia. 117(5)
We performed the first multiple dose study of remimazolam designed to assess both the feasibility of maintaining suitable sedation during colonoscopy and reversing the sedative effects of remimazolam with flumazenil.Healthy volunteers received fentan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8a1000f987f4e890f04c25bf88e5044
https://pubmed.ncbi.nlm.nih.gov/24108261
https://pubmed.ncbi.nlm.nih.gov/24108261
Autor:
Mark T. Worthington, Laurie J. Antonik, Ronald Goldwater, James P. Lees, Karin Wilhelm-Ogunbiyi, Keith M. Borkett, Mack C. Mitchell
Publikováno v:
Survey of Anesthesiology. 58:139-140
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8cce4b0760a79edf01f3c112b9ae41eb
https://doi.org/10.1097/01.sa.0000446259.54853.c6
https://doi.org/10.1097/01.sa.0000446259.54853.c6
Autor:
Thomas W. Sturgill, Mark T. Worthington, Robert M. Rowlett, Melanie J. Schroeder, J. Shabanowitz, Mary G. Harp, Robert DeRose, Carol A. Chrestensen, Donald F. Hunt, Jared W. Pelo
Publikováno v:
American journal of physiology. Gastrointestinal and liver physiology. 295(3)
Tristetraprolin (TTP) is the prototype for a family of RNA binding proteins that bind the tumor necrosis factor (TNF) messenger RNA AU-rich element (ARE), causing deadenylation of the TNF poly(A) tail, RNA decay, and silencing of TNF protein producti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b68c3868da2f98d87743f48e60338b0
https://pubmed.ncbi.nlm.nih.gov/18467502
https://pubmed.ncbi.nlm.nih.gov/18467502
Autor:
Fabio Cominelli, Thomas W. Sturgill, Mary G. Harp, Mark Nyce, Carol A. Chrestensen, Jared W. Pelo, Peter B. Ernst, Theresa T. Pizarro, Mark T. Worthington, Robert M. Rowlett
Publikováno v:
American journal of physiology. Gastrointestinal and liver physiology. 294(2)
The MNK kinases are downstream of both the p38 and ERK MAP kinase pathways and act to increase gene expression. MNK inhibition using the compound CGP57380 has recently been reported to inhibit tumor necrosis factor (TNF) production in macrophage cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::797d651a8b45c8ea3191ee4c9c8d25fe
https://pubmed.ncbi.nlm.nih.gov/18032482
https://pubmed.ncbi.nlm.nih.gov/18032482