Zobrazeno 1 - 10 of 216 pro vyhledávání: '"Mark Stares"'
1
Akademický článek
Biomarkers of systemic inflammation provide additional prognostic stratification in cancers of unknown primary
Autor: Svenja Harvey, Mark Stares, Julie‐Anne Scott, Tharun Joseph Vattam Thottiyil, Alicia‐Marie Conway, Rachel Haigh, Jackie Brown, Gillian Knowles, Sonali Dasgupta, Kai‐Keen Shiu, Claire Mitchell, Colin Barrie, Natalie Cook, Sally Clive
Publikováno v: Cancer Medicine, Vol 13, Iss 3, Pp n/a-n/a (2024)
Abstract Background Biomarkers of systemic inflammation have been shown to predict outcomes in patients with cancer of unknown primary (CUP). We sought to validate these findings in patients with confirmed CUP (cCUP) and explore their role alongside
Externí odkaz: https://doaj.org/article/c5055b489f1a43e8828eba5e72f48749
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2
Akademický článek
Case report: A rare case of immunotherapy induced isolated left CN VI palsy in a patient with unresectable melanoma
Autor: Samantha Su Ping Low, Karim El-Shakankery, Ewan Brown, Alan Christie, Sally McCormack, Mark Stares
Publikováno v: Frontiers in Oncology, Vol 14 (2024)
IntroductionImmune checkpoint inhibitors are the mainstay of treatment in patients with unresectable or metastatic melanoma. Combination immunotherapy with ipilimumab and nivolumab has shown to improve survival outcomes as compared to single agent im
Externí odkaz: https://doaj.org/article/a8034d57ca354d9ab31f1ce0bc27f719
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3
Akademický článek
Initial active surveillance for patients with metastatic renal cell carcinoma: 10 years' experience at a regional cancer Centre
Autor: Mark Stares, Vishwani Chauhan, Jigi Moudgil‐Joshi, Qiu G. Kong, Jahangeer Malik, Aravindhan Sundaramurthy, Tony Elliott, Edward Mains, Steve Leung, Alexander Laird, Stefan N. Symeonides
Publikováno v: Cancer Medicine, Vol 12, Iss 5, Pp 5255-5264 (2023)
Abstract A subset of patients with metastatic renal cell carcinoma (mRCC) follow an indolent disease course and may benefit from initial active surveillance (AS). However, selecting patients suitable for this approach is challenging. To investigate t
Externí odkaz: https://doaj.org/article/94ac9f1ec66e4032b75c9c21bb4569d2
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4
Akademický článek
Hypoalbuminaemia as a Prognostic Biomarker of First-Line Treatment Resistance in Metastatic Non-small Cell Lung Cancer
Autor: Mark Stares, Amanda Swan, Kirsten Cumming, Tze-En Ding, James Leach, Cory Stratton, Findlay Thomson, Colin Barrie, Kirsty MacLennan, Sorcha Campbell, Tamasin Evans, Aisha Tufail, Stephen Harrow, Melanie MacKean, Iain Phillips
Publikováno v: Frontiers in Nutrition, Vol 8 (2021)
Introduction: Despite significant advances in systemic anticancer therapy (SACT) for non-small cell lung cancer (NSCLC), many patients still fail to respond to treatment or develop treatment resistance. Albumin, a biomarker of systemic inflammation a
Externí odkaz: https://doaj.org/article/207d54c6c7194b8f83f5f44fc9aad494
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5
Akademický článek
Optimising Outcomes in Non Small Cell Lung Cancer: Targeting Cancer Cachexia
Autor: Iain Phillips, Mark Stares, Lindsay Allan, Judith Sayers, Richard Skipworth, Barry Laird
Publikováno v: Frontiers in Bioscience-Landmark, Vol 27, Iss 4, p 129 (2022)
Lung cancer is the commonest malignancy worldwide and the leading cause of cancer death. Half of patients with lung cancer present with advanced disease. The number of systemic therapies including immunotherapy and targeted treatment are rapidly incr
Externí odkaz: https://doaj.org/article/795b9c7f3de245d5a4e27917a2bec09b
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7
Characterisation and outcomes of patients referred to a regional cancer of unknown primary team: a 10-year analysis
Autor: Marjory MacLennan, Karin Purshouse, Sally Clive, Mark Stares, C. Barrie, Rachel Haigh, Rebekah Patton, Aoife Gatenby, Jo McGinty, Jenny Irvine, Alan Christie, Gillian Knowles
Publikováno v: British Journal of Cancer
Stares, M, Purshouse, K, Knowles, G, Haigh, R, Irvine, J, Gatenby, A, Patton, R, Mcginty, J, Christie, A, Maclennan, M, Barrie, C & Clive, S 2021, ' Characterisation and outcomes of patients referred to a regional cancer of unknown primary team: a 10-year analysis ', British Journal of Cancer . https://doi.org/10.1038/s41416-021-01544-1
Background In the United Kingdom, national guidance published in 2010 recommended the establishment of specialist teams to improve clinical pathways for patients presenting with malignancies of undefined primary origin (MUO) and cancer of unknown pri
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::777959296c52003605364f57ec5c03bc
http://europepmc.org/articles/PMC8608886
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8
Initial active surveillance for patients with metastatic renal cell carcinoma: 10 years' experience at a regional cancer Centre
Autor: Mark Stares, Vishwani Chauhan, Jigi Moudgil‐Joshi, Qiu G. Kong, Jahangeer Malik, Aravindhan Sundaramurthy, Tony Elliott, Edward Mains, Steve Leung, Alexander Laird, Stefan N. Symeonides
Publikováno v: Stares, M, Chauhan, V, Moudgil-joshi, J, Kong, Q G, Malik, J, Sundaramurthy, A, Elliott, T, Mains, E, Leung, S, Laird, A & Symeonides, S N 2022, ' Initial active surveillance for patients with metastatic renal cell carcinoma: 10 years' experience at a regional cancer Centre ', Cancer Medicine . https://doi.org/10.1002/cam4.5330, https://doi.org/10.1002/cam4.5330
A subset of patients with metastatic renal cell carcinoma (mRCC) follow an indolent disease course and may benefit from initial active surveillance (AS). However, selecting patients suitable for this approach is challenging. To investigate this we so
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbac32be05310c5c8233ce73406f9c76
https://hdl.handle.net/20.500.11820/0e03d910-e14e-42ea-860b-b57e25a2500c
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9
Real-world survival outcomes of patients (pts) treated with 6-weekly pembrolizumab 400mg (pem6w) plus axitinib (axi) for advanced renal cell carcinoma (aRCC)
Autor: Sonam Ansel, Mark Stares, Robert J. Jones, Stefan N. Symeonides, Laura Manson, Anirban Ray-Chaudhuri, Manreet Randhawa, Sarah Slater, Abeera Devasar, Jahangeer Malik, Aravindhan Sundaramurthy, Tony Elliott, Balaji Venugopal
Publikováno v: Journal of Clinical Oncology. 41:645-645
645 Background: The Keynote 426 trial demonstrated 3-weekly pembrolizumab 200mg (pem3w) plus axi twice daily is effective in aRCC. We previously reported real-world experience of pem6w + axi demonstrating a comparable safety profile to pem3w + axi re
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::126ef949b3c0c67ea6dda9d144de41b2
https://doi.org/10.1200/jco.2023.41.6_suppl.645
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10
Predictive value of C reactive protein (CRP) in patients with metastatic renal cell carcinoma (mRCC) treated with pembrolizumab (pembro) and axitinib (axi)
Autor: Aitzaz Qaisar, Balaji Venugopal, Sonam Ansel, Robert J. Jones, Sarah Slater, Stefan N. Symeonides, Jahangeer Malik, Aravindhan Sundaramurthy, Tony Elliott, Abeera Devasar, Mark Stares, Manreet Randhawa
Publikováno v: Journal of Clinical Oncology. 41:716-716
716 Background: CRP, a biomarker of systemic inflammation, has been shown to have prognostic value in numerous tumour types, including mRCC. The combination of the immune check inhibitor (ICI), pembro, and vascular endothelial growth factor receptor
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b7db39cfc880671be591c30354ec0c56
https://doi.org/10.1200/jco.2023.41.6_suppl.716
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