Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Mark Spengler"'
Autor:
Olivia Bonduelle, Andrew Naylor, Toon Stegmann, Charli Smardon, Mario Amacker, Markus Schwaller, Richard Alan Johnson, Desmond Wong, Mark Spengler, Michael Adler, Olga Belova, Béhazine Combadière, Jack Sorrell, Sylvain Fleury, Beena Punnamoottil, Laura M. Mason, Kirk Jeffery, Farien Bhoelan
Publikováno v:
NPJ Vaccines
npj Vaccines, Vol 5, Iss 1, Pp 1-16 (2020)
npj Vaccines, Vol 5, Iss 1, Pp 1-16 (2020)
The main objective of the MACIVIVA European consortium was to develop new Good Manufacturing Practice pilot lines for manufacturing thermostable vaccines with stabilized antigens on influenza virosomes as enveloped virus-like particles. The HIV-1 gp4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04ae282bee05f0e9351cda389437baf7
http://europepmc.org/articles/PMC7235025
http://europepmc.org/articles/PMC7235025
Publikováno v:
Biochemical and Biophysical Research Communications. 488:311-315
Immuno-PCR (IPCR) combines the versatile ELISA antigen detection with ultrasensitive PCR signal amplification, thereby enabling the highly sensitive detection of a broad range of targets with a typically very large dynamic detection range. The quanti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5809be8db41389315a0feea81165078
https://doi.org/10.1016/j.bbrc.2017.04.162
https://doi.org/10.1016/j.bbrc.2017.04.162
Autor:
Michael Adler, Mark Spengler, Andreas Jonas, Beena Punnamoottil, Christian Pieper, Nina Juergens
Publikováno v:
Frontiers in Pharmacology. 8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6412205ac1a5422ac3dd82f8de0a1dce
https://doi.org/10.3389/conf.fphar.2017.62.00021
https://doi.org/10.3389/conf.fphar.2017.62.00021
Publikováno v:
Frontiers in Pharmacology. 8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b061cf4911cee154f2a43a7ed73bb8a2
https://doi.org/10.3389/conf.fphar.2017.62.00007
https://doi.org/10.3389/conf.fphar.2017.62.00007
Publikováno v:
Frontiers in Pharmacology. 8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0667ba55ea6ec9c5e2f89f416da6ccf2
Autor:
Alvydas Mikulskis, Mark Spengler, Yao Zhuang, Alison Joyce, Saloumeh K Fischer, Tong-Yuan Yang, Marianne Scheel Fjording
Publikováno v:
The AAPS Journal. 17:93-101
Ligand binding assays (LBAs) have been the method of choice for protein analyte measurements for more than four decades. Over the years, LBA methods have improved in sensitivity and achieved larger dynamic ranges by using alternative detection system
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ec5c7f168fbbf4f9b27183c805425fd
https://doi.org/10.1208/s12248-014-9682-8
https://doi.org/10.1208/s12248-014-9682-8
Publikováno v:
Advanced Functional Materials. 17:437-442
DNA oligonucleotides are extraordinarily well suited as linkers for the programmable assembly of nanoparticles. To extend the scope of DNA-directed particle assembly, a 70 nm DNA linker molecule for the DNA-directed assembly of gold nanoparticles is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fde6535684279f7dbaeff5b0bfbe22f2
https://doi.org/10.1002/adfm.200600694
https://doi.org/10.1002/adfm.200600694
Publikováno v:
Analyst, 140 (18), 6175-6194
Recombinant DNA technology and corresponding innovations in molecular biology, chemistry and medicine have led to novel therapeutic biomacromolecules as lead candidates in the pharmaceutical drug development pipelines. While monoclonal antibodies and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::010778d767d55dfda784bcdb4743c105
https://pubmed.ncbi.nlm.nih.gov/26196036
https://pubmed.ncbi.nlm.nih.gov/26196036
Publikováno v:
Biochemical and biophysical research communications. 387(2)
The administration of therapeutic proteins often induces immunogenic response and thus formation of anti-drug antibodies (ADA), which can neutralize the drug's therapeutic effect and may even cause serious health problems. We here report on the emplo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72040833eecf1cb8a18edb0c942ec753
https://pubmed.ncbi.nlm.nih.gov/19577544
https://pubmed.ncbi.nlm.nih.gov/19577544
Autor:
Mark Spengler, Heiko Hayen, Christof M. Niemeyer, Valerie J. Gandubert, Kersten S. Rabe, Michael Erkelenz, Joachim Müller
Publikováno v:
Chembiochem : a European journal of chemical biology. 10(4)
Cytochrome P450 enzymes are known to catalyze a variety of reactions that are difficult to perform by standard organic synthesis, such as the oxidation of unactivated C--C bonds. Cytochrome P450 enzymes can also be used in artificial systems in which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::713047e71b84e84f7af362bccb31834e
https://pubmed.ncbi.nlm.nih.gov/19241405
https://pubmed.ncbi.nlm.nih.gov/19241405