Classical Oncogenes and Tumor Suppressor Genes: A Comparative Genomics Perspective

Autor: Oxana K. Pickeral, Jonathan Z. Li, Ian Barrow, Mark S. Boguski, Wojciech Makałowski, Jiong Zhang

Publikováno v: Neoplasia: An International Journal for Oncology Research, Vol 2, Iss 3, Pp 280-286 (2000)

We have curated a reference set of cancer-related genes and reanalyzed their sequences in the light of molecular information and resources that have become available since they were first cloned. Homology studies were carried out for human oncogenes

Externí odkaz: https://doaj.org/article/627cd542fa514ea9b010cb0e21e11dd5

Genome-wide atlas of gene expression in the adult mouse brain

Autor: Aneta Czaplinska, Aimee L. Desaki, Maureen P. Howell, Bryan I. Smith, Kevin S. Brockway, Ben J. Duncan, Annabel R. Laramee, Shanna R. Fischer, Tsuey-Ming Chen, Reena Kawal, Nancy Ao, Agnes J. Liang, Amy Bernard, Casey Faber, Ed S. Lein, Geralyn J. Orta, Kevin R. Halverson, Jennifer G. Dougherty, Chinh Dang, Cliff Frensley, Caroline C. Overly, Judith J. Morgan, Murat B. Yaylaoglu, Mark S. Boguski, Lee R. Varnam, Susan M. Sunkin, Crissa K. Wolkey, Amanda Ebbert, Matthew J.A. Wood, Paul Wohnoutka, Benjamin A.C. Facer, Li Chen, Jesse Michaels, James H. Lake, Carey D. Teemer, Rebecca A. Johnson, Axel Visel, Marty Mortrud, Michael Hawrylycz, Christina Thaller, Nerick Mosqueda, Victoria Y. Wong, Tim A. Dolbeare, Xu Feng Yuan, Mei Chi Chin, Marcos J. Ruiz, Carol L. Thompson, Katherine Schaffnit, Theresa A. Zwingman, Sayan Dev Pathak, Tracy Lemon, Lydia Ng, Jimmy Chong, Lili K. Estin, Simon Smith, Rob Young, Kirk D. Larsen, Joshua J. Royall, Randy Ng, Rachel H. Knapik, Mikael Ayres, Nick Dee, Sheana Parry, Ray M. Whitlock, Kenda-Ruth Stumpf, Nadiya V. Shapovalova, Emi J. Byrnes, Taz Sivisay, Matthew R. Hart, Chihchau L. Kuan, Owen C. Pearson, Ellen Diep, Nadia R. Sarno, Madhavi Sutram, Andrew F. Boe, Clifford R. Slaughterbeck, Zackery L. Riley, Rebecca J. Morgan, Hong-Wei Dong, Tsega Desta, Patrick T. Karr, Andy J. Sodt, John G. Hohmann, Suvro Datta, Stephen A. Rowland, Tu H. Pak, Ralph B. Puchalski, Lin Chen, Nick N. Stewart, Ying Liu, Hannah R. Rockett, Brian L. Youngstrom, Darren P. Jeung, Lon T. Luong, Matthew J. Donelan, Amy Bensinger, Katie J. Glattfelder, Bin Zhang, Allan R. Jones, Gregor Eichele, Rick Fields, Sabrina N. Gates, Kimberly A. Smith, Angelene Tam, Brian E. Crook, Tim P. Fliss, Jolene Kidney, Christopher Lau

Publikováno v: Nature. 445:168-176

Molecular approaches to understanding the functional circuitry of the nervous system promise new insights into the relationship between genes, brain and behaviour. The cellular diversity of the brain necessitates a cellular resolution approach toward

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2f1bcef3c42664230a6393b0bffc31d
https://doi.org/10.1038/nature05453

A Call to Action

Autor: Richard L. Haspel, Lauren C. Briere, Peter J. Tonellato, Karen Marchand, James L. Connolly, Ramy Arnaout, Jeffrey E. Saffitz, Mark S. Boguski, Sibel Kantarci

Publikováno v: American Journal of Clinical Pathology. 133:832-834

Genomics and "medical sequencing" will revolutionize clinical laboratory diagnostics as the foundation for the new era of personalized medicine. However, the medical profession lags far behind the technology and business communities in recognizing an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::731d580369906a1879851a62b67db83b
https://doi.org/10.1309/ajcpn6q1qkclykxm

Frequent Human Genomic DNA Transduction Driven by LINE-1 Retrotransposition

Autor: Jef D. Boeke, Oxana K. Pickeral, Wojciech Makalowski, Mark S. Boguski

Publikováno v: Genome Research. 10:411-415

Human L1 retrotransposons can produce DNA transduction events in which unique DNA segments downstream of L1 elements are mobilized as part of aberrant retrotransposition events. That L1s are capable of carrying out such a reaction in tissue culture c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dda9b966d42e46caa3ce1efc509b2295
https://doi.org/10.1101/gr.10.4.411

Human and nematode orthologs — lessons from the analysis of 1800 human genes and the proteome of Caenorhabditis elegans

Autor: Wojciech Makalowski, Sarah J. Wheelan, Laurent Duret, Mark S. Boguski

Publikováno v: Gene. 238:163-170

Recently, we have defined and analyzed over 1800 orthologous human and rodent genes. Here we extend this work to compare human and Caenorhabditis elegans coding sequences. 1880 human proteins were compared with about 20 000 predicted nematode protein

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebaaba78611ec23f72b4f9e3d459203c
https://doi.org/10.1016/s0378-1119(99)00298-x