Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Mark S de Souza"'
Autor:
Siriwat Akapirat, Chitraporn Karnasuta, Sandhya Vasan, Supachai Rerks-Ngarm, Punnee Pitisuttithum, Sirinan Madnote, Hathairat Savadsuk, Surawach Rittiroongrad, Jiraporn Puangkaew, Sanjay Phogat, James Tartaglia, Faruk Sinangil, Mark S de Souza, Jean-Louis Excler, Jerome H Kim, Merlin L Robb, Nelson L Michael, Viseth Ngauy, Robert J O'Connell, Nicos Karasavvas, RV305 Study Group
Publikováno v:
PLoS ONE, Vol 13, Iss 4, p e0196397 (2018)
Sexual transmission is the principal driver of the human immunodeficiency virus (HIV) pandemic. Understanding HIV vaccine-induced immune responses at mucosal surfaces can generate hypotheses regarding mechanisms of protection, and may influence vacci
Externí odkaz:
https://doaj.org/article/b6a6cce028b540d6b3b05c44c133477e
Autor:
Prossy Naluyima, Leigh Anne Eller, Benson J Ouma, Denis Kyabaggu, Peter Kataaha, David Guwatudde, Hannah Kibuuka, Fred Wabwire-Mangen, Merlin L Robb, Nelson L Michael, Mark S de Souza, Johan K Sandberg, Michael A Eller
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0146196 (2016)
Management of patient care and interpretation of research data require evaluation of laboratory results in the context of reference data from populations with known health status to adequately diagnose disease or make a physiological assessment. Few
Externí odkaz:
https://doaj.org/article/5174abd58cda4ed986d2039bbd147e42
Autor:
Silvia Ratto-Kim, Mark S de Souza, Jeffrey R Currier, Nicos Karasavvas, John Sidney, Morgane Rolland, Anais Valencia-Micolta, Sirinan Madnote, Alessandro Sette, Sorachai Nitayaphan, Punnee Pitisuttuthum, Jaranit Kaewkungwal, Supachai Rerks-Ngarm, Robert O'Connell, Nelson Michael, Merlin L Robb, Mary Marovich, Jerome H Kim
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0115582 (2015)
We performed fine epitope mapping of the CD4+ responses in the ALVAC-HIV-AIDSVAX B/E prime-boost regimen in the Thai Phase III trial (RV144). Non-transformed Env-specific T cell lines established from RV144 vaccinees were used to determine the fine e
Externí odkaz:
https://doaj.org/article/3f48103a5af34f3c907fa9c1c7b22e76
Autor:
Alexandra Schuetz, Claire Deleage, Irini Sereti, Rungsun Rerknimitr, Nittaya Phanuphak, Yuwadee Phuang-Ngern, Jacob D Estes, Netanya G Sandler, Suchada Sukhumvittaya, Mary Marovich, Surat Jongrakthaitae, Siriwat Akapirat, James L K Fletscher, Eugene Kroon, Robin Dewar, Rapee Trichavaroj, Nitiya Chomchey, Daniel C Douek, Robert J O Connell, Viseth Ngauy, Merlin L Robb, Praphan Phanuphak, Nelson L Michael, Jean-Louis Excler, Jerome H Kim, Mark S de Souza, Jintanat Ananworanich, RV254/SEARCH 010 and RV304/SEARCH 013 Study Groups
Publikováno v:
PLoS Pathogens, Vol 10, Iss 12, p e1004543 (2014)
Mucosal Th17 cells play an important role in maintaining gut epithelium integrity and thus prevent microbial translocation. Chronic HIV infection is characterized by mucosal Th17 cell depletion, microbial translocation and subsequent immune-activatio
Externí odkaz:
https://doaj.org/article/c4bf7dcd5024440a8441e7e34b20bf4c
Autor:
Nicholas J Steers, Silvia Ratto-Kim, Mark S de Souza, Jeffrey R Currier, Jerome H Kim, Nelson L Michael, Carl R Alving, Mangala Rao
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e42579 (2012)
Antigen processing involves many proteolytic enzymes such as proteasomes and cathepsins. The processed antigen is then presented on the cell surface bound to either MHC class I or class II molecules and induces/interacts with antigen-specific CD8+ an
Externí odkaz:
https://doaj.org/article/bc5d0f4d0bff497f97e85c38897a2281
Autor:
Michael A Eller, Kim G Blom, Veronica D Gonzalez, Leigh Anne Eller, Prossy Naluyima, Oliver Laeyendecker, Thomas C Quinn, Noah Kiwanuka, David Serwadda, Nelson K Sewankambo, Boonrat Tasseneetrithep, Maria J Wawer, Ronald H Gray, Mary A Marovich, Nelson L Michael, Mark S de Souza, Fred Wabwire-Mangen, Merlin L Robb, Jeffrey R Currier, Johan K Sandberg
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e18779 (2011)
HIV-1 disease progression is associated with persistent immune activation. However, the nature of this association is incompletely understood. Here, we investigated immune activation in the CD4 T cell compartment of chronically HIV-1 infected individ
Externí odkaz:
https://doaj.org/article/80b16ccc3560435293e8e3c8573e877f
Autor:
Jeffrey R Currier, Viseth Ngauy, Mark S de Souza, Silvia Ratto-Kim, Josephine H Cox, Victoria R Polonis, Patricia Earl, Bernard Moss, Sheila Peel, Bonnie Slike, Somchai Sriplienchan, Prasert Thongcharoen, Robert M Paris, Merlin L Robb, Jerome Kim, Nelson L Michael, Mary A Marovich
Publikováno v:
PLoS ONE, Vol 5, Iss 11, p e13983 (2010)
We conducted a Phase I randomized, dose-escalation, route-comparison trial of MVA-CMDR, a candidate HIV-1 vaccine based on a recombinant modified vaccinia Ankara viral vector expressing HIV-1 genes env/gag/pol. The HIV sequences were derived from cir
Externí odkaz:
https://doaj.org/article/3c3b667ce79e493a93c838e4082cfdfa
Autor:
Rukia S Kibaya, Christian T Bautista, Frederick K Sawe, Douglas N Shaffer, Warren B Sateren, Paul T Scott, Nelson L Michael, Merlin L Robb, Deborah L Birx, Mark S de Souza
Publikováno v:
PLoS ONE, Vol 3, Iss 10, p e3327 (2008)
The conduct of Phase I/II HIV vaccine trials internationally necessitates the development of region-specific clinical reference ranges for trial enrollment and participant monitoring. A population based cohort of adults in Kericho, Kenya, a potential
Externí odkaz:
https://doaj.org/article/2d767b7229d54e6c9f4350294401b402
Autor:
Leigh Anne Eller, Michael A Eller, Benson Ouma, Peter Kataaha, Denis Kyabaggu, Richard Tumusiime, Joseph Wandege, Ronald Sanya, Warren B Sateren, Fred Wabwire-Mangen, Hannah Kibuuka, Merlin L Robb, Nelson L Michael, Mark S de Souza
Publikováno v:
PLoS ONE, Vol 3, Iss 12, p e3919 (2008)
BACKGROUND: Clinical trials are increasingly being conducted internationally. In order to ensure enrollment of healthy participants and proper safety evaluation of vaccine candidates, established reference intervals for clinical tests are required in
Externí odkaz:
https://doaj.org/article/d27685a847dc4f50b961916bbc05925e
Autor:
Dominic, Paquin-Proulx, Kerri G, Lal, Yuwadee, Phuang-Ngern, Matthew, Creegan, Andrey, Tokarev, Suchada, Suhkumvittaya, Aljawharah, Alrubayyi, Eugène, Kroon, Suteeraporn, Pinyakorn, Bonnie M, Slike, Diane L, Bolton, Shelly J, Krebs, Leigh Anne, Eller, Chayada, Sajjaweerawan, Amélie, Pagliuzza, Nicolas, Chomont, Rungsun, Rerknimitr, Nitiya, Chomchey, Nittaya, Phanuphak, Mark S, de Souza, Nelson L, Michael, Merlin L, Robb, Jintanat, Ananworanich, Johan K, Sandberg, Michael A, Eller, Alexandra, Schuetz
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Evidence suggests that HIV-1 disease progression is determined in the early stages of infection. Here, preinfection invariant natural killer T (iNKT) cell levels were predictive of the peak viral load during acute HIV-1 infection (AHI).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::527aab0e156c96177b08874656a772c1
https://pubmed.ncbi.nlm.nih.gov/34753817
https://pubmed.ncbi.nlm.nih.gov/34753817