Zobrazeno 1 - 10
of 105
pro vyhledávání: '"Mark S, Gresnigt"'
Autor:
Sebastian Schaefer, Raghav Vij, Jakob L. Sprague, Sophie Austermeier, Hue Dinh, Peter R. Judzewitsch, Sven Müller-Loennies, Taynara Lopes Silva, Eric Seemann, Britta Qualmann, Christian Hertweck, Kirstin Scherlach, Thomas Gutsmann, Amy K. Cain, Nathaniel Corrigan, Mark S. Gresnigt, Cyrille Boyer, Megan D. Lenardon, Sascha Brunke
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-22 (2024)
Abstract More than two million people worldwide are affected by life-threatening, invasive fungal infections annually. Candida species are the most common cause of nosocomial, invasive fungal infections and are associated with mortality rates above 4
Externí odkaz:
https://doaj.org/article/4855006eb2384c85b16fca8c8d5c88bf
Autor:
Martin Jaeger, Axel Dietschmann, Sophie Austermeier, Sude Dinçer, Pauline Porschitz, Larsen Vornholz, Ralph J.A. Maas, Evelien G.G. Sprenkeler, Jürgen Ruland, Stefan Wirtz, Tania Azam, Leo A.B. Joosten, Bernhard Hube, Mihai G. Netea, Charles A. Dinarello, Mark S. Gresnigt
Publikováno v:
Virulence, Vol 15, Iss 1 (2024)
ABSTRACTOur immune system possesses sophisticated mechanisms to cope with invading microorganisms, while pathogens evolve strategies to deal with threats imposed by host immunity. Human plasma protein α1-antitrypsin (AAT) exhibits pleiotropic immune
Externí odkaz:
https://doaj.org/article/69c249b8532c4a85b4278d546bfe2770
Autor:
Marisa Valentine, Paul Rudolph, Axel Dietschmann, Antzela Tsavou, Selene Mogavero, Sejeong Lee, Emily L. Priest, Gaukhar Zhurgenbayeva, Nadja Jablonowski, Sandra Timme, Christian Eggeling, Stefanie Allert, Edward Dolk, Julian R. Naglik, Marc T. Figge, Mark S. Gresnigt, Bernhard Hube
Publikováno v:
mBio, Vol 15, Iss 3 (2024)
ABSTRACT Candida albicans can cause mucosal infections in humans. This includes oropharyngeal candidiasis, which is commonly observed in human immunodeficiency virus infected patients, and vulvovaginal candidiasis (VVC), which is the most frequent ma
Externí odkaz:
https://doaj.org/article/eeea74a6fcf24d4883ccc5fbc280c9a4
Publikováno v:
Frontiers in Fungal Biology, Vol 4 (2023)
Externí odkaz:
https://doaj.org/article/57518534f35f417082d1371b69edd411
Autor:
Raquel Alonso-Roman, Antonia Last, Mohammad H. Mirhakkak, Jakob L. Sprague, Lars Möller, Peter Großmann, Katja Graf, Rena Gratz, Selene Mogavero, Slavena Vylkova, Gianni Panagiotou, Sascha Schäuble, Bernhard Hube, Mark S. Gresnigt
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Commensal bacteria such as Lactobacillus rhamnosus can inhibit the pathogenicity of the fungus Candida albicans. Here, Alonso-Roman et al. investigate the interplay between C. albicans, L. rhamnosus and intestinal epithelial cells, showing that chang
Externí odkaz:
https://doaj.org/article/4b43000037904e2aabfc1a7cd0eee186
Autor:
Vasiliki Matzaraki, Alexandra Beno, Martin Jaeger, Mark S. Gresnigt, Nick Keur, Collins Boahen, Cristina Cunha, Samuel M. Gonçalves, Luis Leite, João F. Lacerda, António Campos, Jr., Frank L. van de Veerdonk, Leo Joosten, Mihai G. Netea, Agostinho Carvalho, Vinod Kumar
Publikováno v:
Redox Biology, Vol 55, Iss , Pp 102391- (2022)
Reactive oxygen species (ROS) are an essential component of the host defense against fungal infections. However, little is known about how common genetic variation affects ROS-mediated antifungal host defense. In the present study, we investigated th
Externí odkaz:
https://doaj.org/article/fcd8061a616c4cb0bb8c1cf57bf65f74
Publikováno v:
PLoS Pathogens, Vol 18, Iss 8, p e1010740 (2022)
Externí odkaz:
https://doaj.org/article/91af9288564f46769aa99727fe4cfb6e
Autor:
Mariolina Bruno, Intan M.W. Dewi, Vicky Matzaraki, Rob ter Horst, Marina Pekmezovic, Berenice Rösler, Laszlo Groh, Rutger J. Röring, Vinod Kumar, Yang Li, Agostinho Carvalho, Mihai G. Netea, Jean-Paul Latgé, Mark S. Gresnigt, Frank L. van de Veerdonk
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss , Pp 647-663 (2021)
Candidiasis, aspergillosis, and mucormycosis cause the majority of nosocomial fungal infections in immunocompromised patients. Using an unbiased transcriptional profiling in PBMCs exposed to the fungal species causing these infections, we found a cor
Externí odkaz:
https://doaj.org/article/d6e9c6589cca465baf966bc074e18354
Autor:
Marina Pekmezovic, Ann-Kristin Kaune, Sophie Austermeier, Sophia U. J. Hitzler, Selene Mogavero, Hrant Hovhannisyan, Toni Gabaldón, Mark S. Gresnigt, Bernhard Hube
Publikováno v:
PLoS Pathogens, Vol 17, Iss 10 (2021)
The opportunistic pathogen Candida glabrata is the second most frequent causative agent of vulvovaginal candidiasis (VVC), a disease that affects 70–75% of women at least once during their life. However, C. glabrata is almost avirulent in mice and
Externí odkaz:
https://doaj.org/article/c51d4598ebda49c1bf0b710fc4b9ddbf
Publikováno v:
PLoS Pathogens, Vol 17, Iss 7, p e1009710 (2021)
Externí odkaz:
https://doaj.org/article/5e93289fdfb54552b4a842a4199612b8