Mice deficient in galectin-1 exhibit attenuated physiological responses to chronic hypoxia-induced pulmonary hypertension

Autor: Edward C. Dempsey, David Irwin, Charles Ivester, Moira Hagen, Katharine A Young, Joseph T. Crossno, David Case, Julie W. Harral, Susan M. Majka, Kenneth G. Morris, Françoise Poirier, Masatoshi Imamura, Michelle Carr, Mark Roedersheimer, James West, Abby Patterson, Milene Saavedra

Publikováno v: American Journal of Physiology-Lung Cellular and Molecular Physiology
American Journal of Physiology-Lung Cellular and Molecular Physiology, American Physiological Society, 2007, 292 (1), pp.L154-64. ⟨10.1152/ajplung.00192.2006⟩

Pulmonary hypertension (PH) is characterized by sustained vasoconstriction, with subsequent extracellular matrix (ECM) production and smooth muscle cell (SMC) proliferation. Changes in the ECM can modulate vasoreactivity and SMC contraction. Galectin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a6ef588e8020e14e097c078c0ada105
https://doi.org/10.1152/ajplung.00192.2006

Solving the Measurement Problem and then Steppin' Out over the Line Riding the Rarest Italian: Crossing the Streams to Retrieve Stable Bioactivity in Majorana Bound States of Dialy zed Human Platelet Lysates

Autor: Mark Roedersheimer

Publikováno v: The Open Neurology Journal

Exhaustive dialysis (ED) of lysed human platelets against dilute HCl yields stable angiogenic activity. Dialysis against a constrained external volume, with subsequent relaxation of the separation upon opening the dialysis bag, produces material able

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f333a6e49d70a716cb0886d31b6da82
https://pubmed.ncbi.nlm.nih.gov/26191092

Extracellular ATP is a pro‐angiogenic factor for systemic microvascular endothelial cells

Autor: Evgenia V. Gerasimovskaya, Kurt R. Stenmark, Heather Woodward, Mark Roedersheimer, Doug A. Tucker

Publikováno v: The FASEB Journal. 22

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cec72398d3f376fe97012c28006ff320
https://doi.org/10.1096/fasebj.22.1_supplement.49.8

Complementary effects of extracellular nucleotides and platelet-derived extracts on angiogenesis of vasa vasorum endothelial cells in vitro and subcutaneous Matrigel plugs in vivo

Autor: Evgenia V. Gerasimovskaya, Nana Burns, Kurt R. Stenmark, Hala Nijmeh, Asya A Sidiakova, Mark Roedersheimer

Publikováno v: Vascular Cell

Background Platelets contribute to vascular homeostasis and angiogenesis through the release of multiple growth factors, cytokines and nucleotides, such as ATP and ADP. Recent reports have demonstrated a marked growth-promoting effect of total platel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65c2738a1f886a01ffd687e888b93f88
https://doi.org/10.1186/2045-824x-3-4