Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Mark Richard Ashton"'
Autor:
Yun-Chia Sophia Chen, Gopichand Yalamanchili, Christopher John Yarnold, Stephen M.G. Duff, Edward Andrew Boyd, Mark Richard Ashton, Daniel M. Walker, Bruce C. Hamper, Frederick Arthur Brookfield, Brad J. Fabbri, Claire A. CaJacob
Publikováno v:
Pesticide Biochemistry and Physiology. 88:1-13
The carboxyterminal processing protease of D1 protein (CtpA) is predicted to be an excellent target for the discovery of a general broad-spectrum herbicide. Directed and random screening of compounds against recombinant spinach CtpA (rCtpA) has led t
Autor:
Luzheng Xue, Mark Richard Ashton, Frederick Arthur Brookfield, Shân L. Gyles, Mark Cowley Whittaker, Roy Pettipher, Richard Edward Armer, Edward Andrew Boyd, Michael G. Hunter, Christopher James Brennan, Philip Andrew Hay, David Middlemiss, Lucien Gazi
Publikováno v:
Journal of Medicinal Chemistry. 48:6174-6177
Prostaglandin D2 (PGD2) acting at the CRTH2 receptor (chemoattractant receptor-homologous molecule expressed on Th2 cells) has been linked with a variety of allergic and other inflammatory diseases. We describe a family of indole-1-sulfonyl-3-acetic
Autor:
Russell J. Thomas, Michael H. Charlton, Mark Richard Ashton, Matthias Schwarz, Mark Whittaker
Publikováno v:
Combinatorial chemistryhigh throughput screening. 7(5)
Virtual screening methods using structure-based, pharmacophore-based and descriptor based protocols may be used to identify ligands for the G-protein coupled receptor target family. A complementary approach is the synthesis and screening of compound