Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Mark R. Plummer"'
Publikováno v:
J Neurosci
Neural response properties that typify primary sensory afferents are critical to fully appreciate because they establish and, ultimately represent, the fundamental coding design used for higher-level processing. Studies illuminating the center-surrou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8a33ebd0da440994ceb9617144bc411
https://doi.org/10.1523/jneurosci.0924-20.2021
https://doi.org/10.1523/jneurosci.0924-20.2021
Publikováno v:
J Neurophysiol
A defining feature of type I primary auditory afferents that compose ∼95% of the spiral ganglion is their intrinsic electrophysiological heterogeneity. This diversity is evident both between and within unitary, rapid, and slow adaptation (UA, RA, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41b02458edabab8946602dfa9d98cdec
https://europepmc.org/articles/PMC9054264/
https://europepmc.org/articles/PMC9054264/
Autor:
Karl Herrup, Aifang Cheng, Teng Zhao, Shengwang Du, Mark R. Plummer, Yu Ray Han, Graham Vail, Michael Ming-tak Loy
Publikováno v:
Journal of neurophysiology. 116(1)
Ataxia telangiectasia is a multisystemic disorder that includes a devastating neurodegeneration phenotype. The ATM (ataxia-telangiectasia mutated) protein is well-known for its role in the DNA damage response, yet ATM is also found in association wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ebca30c5dfe235f1a3adc449737e4c0
https://pubmed.ncbi.nlm.nih.gov/27075534
https://pubmed.ncbi.nlm.nih.gov/27075534
Publikováno v:
Journal of Neurophysiology. 105:2364-2374
The adult pattern of neural connectivity is shaped by repulsive and attractive factors, many of which are modulated by activity. Although much is known about the actions of these factors when studied in isolation, little is known about how they inter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0f4e3243f35f79199b421d5ca906df0
https://doi.org/10.1152/jn.00564.2010
https://doi.org/10.1152/jn.00564.2010
Publikováno v:
Current Biology. 19(24):2091-2096
ATM is a PI3 kinase family member that plays an important role in DNA double strand break repair. ATM deficiency leads to ataxia-telangiectasia (AT), a syndrome involving cancer susceptibility, hypersensitivity to ionizing radiation, immune deficienc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52b7837e12f2335e87a1ebdb77f85fbc
Autor:
Mark R. Plummer, Patrick J. Sinko, Yong-Jiu Jin, Xiaoping Zhang, Simi Gunaseelan, Shahriar Pooyan
Publikováno v:
Molecular Pharmaceutics. 6:836-848
Cell-penetrating peptides (CPPs) can enter many types of cells and have become useful tools for introducing a variety of cargo such as exogenous peptides, proteins, and nucleic acids into cultured cells in vitro. Tat CPPs derived from the HIV-1 Tat p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15b5789dc7e7fb8db5b41bdcd90124fa
https://doi.org/10.1021/mp800121f
https://doi.org/10.1021/mp800121f
Publikováno v:
Journal of Neurophysiology. 100:3264-3274
Brain-derived neurotrophic factor (BDNF), a potent modulator of synaptic transmission, is known to influence associative synaptic plasticity and refinement of neural connectivity. We now show that BDNF modulation of glutamate currents in hippocampal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e2319f3f3bc8fd30ce636266b2a905f
https://doi.org/10.1152/jn.90418.2008
https://doi.org/10.1152/jn.90418.2008
Autor:
Loyal A. Goff, Cynthia Camarillo, Ronald P. Hart, Kevin Thompson, Yu R. Han, Mavis R. Swerdel, Jonathan Davila, Hedong Li, Caixia Bi, Martin Grumet, Mark R. Plummer, Christopher L. Ricupero
Publikováno v:
Developmental Neurobiology. 68:1549-1564
We have generated clones (L2.3 and RG3.6) of neural progenitors with radial glial properties from rat E14.5 cortex that differentiate into astrocytes, neurons, and oligodendrocytes. Here, we describe a different clone (L2.2) that gives rise exclusive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f669672e916af3a98f1a6315d2f3893
https://doi.org/10.1002/dneu.20679
https://doi.org/10.1002/dneu.20679
Publikováno v:
Developmental Neurobiology. 67:1687-1698
Neurotrophin activation of Trk receptors elicits diverse effects on neuronal survival, differentiation, and synaptic plasticity. One of the central questions is how specificity is encoded in neurotrophin receptor signaling and actions. A unique downs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0ba17365015bccf0aca540d5c8a9174
https://doi.org/10.1002/dneu.20542
https://doi.org/10.1002/dneu.20542
Ataxia-telangiectasia (AT) is an autosomal-recessive multisystem neurodegenerative disorder characterized by prominent involvement of cerebellar Purkinje cells. Immune deficiency is associated with increased risk of recurrent infections and cancer. M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::94925a288d17e9a0f6fa9834d77fa0ed
https://doi.org/10.1016/b978-0-12-405195-9.00066-4
https://doi.org/10.1016/b978-0-12-405195-9.00066-4