Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Mark R. McCall"'
Publikováno v:
Journal of Lipid Research, Vol 40, Iss 1, Pp 85-92 (1999)
Apolipoprotein E (apoE) is synthesized and secreted by arterial macrophages while apolipoprotein A-I (apoA-I) is present in surrounding interstitial fluids. Both apolipoproteins play important roles in macrophage cholesterol homeostasis by forming li
Externí odkaz:
https://doaj.org/article/f8879e16ad5b4e4cb519aa25e45ad6c2
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 21:1040-1045
Abstract —Modification of low density lipoprotein (LDL) by myeloperoxidase-generated HOCl has been implicated in human atherosclerosis. Incubation of LDL with HOCl generates several reactive intermediates, primarily N -chloramines, which may react
Autor:
Ronald M. Krauss, Mark R. McCall, Trudy M. Forte, Diane L. Tribble, Yoshikazu Takanami, Michael La Belle
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 1437:23-36
Platelet-activating factor acetylhydrolase (PAF-AH) is transported by lipoproteins in plasma and is thought to possess both anti-inflammatory and anti-oxidative activity. It has been reported that PAF-AH is recovered primarily in small, dense LDL and
Autor:
L J Stoltzfus, Giulia Chiesa, C R Sirtori, G Franceschini, Trudy M. Forte, John K. Bielicki, Mark R. McCall, Edward M. Rubin
Publikováno v:
Journal of Lipid Research, Vol 38, Iss 11, Pp 2314-2321 (1997)
Human carriers of apolipoprotein A-I(Milano) (Arg173 --> Cys substitution in apolipoprotein A-I) are characterized by an HDL deficiency in which small, dense HDL accumulate in plasma. Because affected individuals are heterozygous for this mutation, t
Publikováno v:
Journal of Lipid Research, Vol 37, Iss 5, Pp 1076-1085 (1996)
Apolipoprotein A-I (apoA-I) incubated with CHO cells assembles three major nascent lipid complexes with diameters of 7.3, 9, and 11 nm. Previous studies suggested that the smaller nascent particles were precursors for the larger nascent ones. To test
Publikováno v:
Journal of Lipid Research, Vol 37, Iss 5, Pp 1012-1021 (1996)
The oxidation of low density lipoproteins (LDL) has been implicated in the development of atherosclerosis. As a variety of highly reactive lipid peroxidation products can transfer from oxidized LDL to HDL, we evaluated the potential deleterious effec
Publikováno v:
Journal of Lipid Research, Vol 36, Iss 2, Pp 322-331 (1995)
Cigarette smokers have reduced levels of plasma high density lipoprotein (HDL) compared to nonsmokers and are at risk of premature cardiovascular disease. Previous work from this laboratory has shown that exposure of human plasma to gas-phase cigaret
Publikováno v:
Journal of Lipid Research, Vol 36, Iss 1, Pp 148-157 (1995)
Studies were carried out to determine whether apolipoprotein (apo) A-II, like apoA-I, can recruit phospholipid and cholesterol from cell membranes, thereby forming nascent apoA-II-specific HDL. ApoA-II and apoA-I were purified from plasma and each wa
Autor:
Mark R. McCall, Trudy M. Forte
Publikováno v:
Current Opinion in Lipidology. 5:354-364
The inverse relationship between HDL and apolipoprotein A-I concentrations and the risk for premature atherosclerosis is well established, but the mechanism whereby apolipoprotein A-I offers protection is still somewhat elusive. Recent studies sugges
Publikováno v:
Journal of Lipid Research, Vol 34, Iss 2, Pp 317-324 (1993)
The ability of lipid-free human apoA-I expressed by transfected Chinese hamster ovary (CHO) cells to form apoA-I-lipid complexes extracellularly when incubated with CHO cell monolayers was investigated. Lipid-free apoA-I was incubated with nontransfe