Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Mark R. Klein"'
Autor:
Joost A Aalberse, Berber Kapitein, Sytze de Roock, Mark R Klein, Wilco de Jager, Ruurd van der Zee, Maarten O Hoekstra, Femke van Wijk, Berent J Prakken
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e24119 (2011)
BACKGROUND: To prevent harmful autoimmunity most immune responses to self proteins are controlled by central and peripheral tolerance. T cells specific for a limited set of self-proteins such as human heat shock protein 60 (HSP60) may contribute to p
Externí odkaz:
https://doaj.org/article/655d914378b049f98944337f9f9b636e
Autor:
Berent J. Prakken, Lianne M. Haveman, Marc Bierings, Elisabeth Legger, Henny G. Otten, Wilco de Jager, Salvatore Albani, Mark R. Klein, Alessandro Sette, W. Kuis
Publikováno v:
International Immunology. 18:1521-1529
Adenovirus can cause fatal infections in the immunocompromised host. To date, no effective anti-viral therapy is available. Adoptive therapy with adenovirus-specific T cells could be a promising treatment, but requires the identification of such T ce
Autor:
Berent J. Prakken, Mark R. Klein, Nico M. Wulffraat, Gijs Teklenburg, Ger J. A. Arkesteijn, Gisella Puga Yung, S. Albani, Bas Vastert, Ismé M. de Kleer, Wietse Kuis
Publikováno v:
Blood. 107:1696-1702
Despite a rapidly accumulating clinical experience with autologous stem cell transplantation (ASCT) as a treatment for severe refractory autoimmune disease, data on the mechanisms by which ASCT induces immune tolerance are still very scarce. In this
Autor:
Sylvia, Kamphuis, Kolbrún, Hrafnkelsdóttir, Mark R, Klein, Wilco, de Jager, Margje H, Haverkamp, Jolanda H M, van Bilsen, Salvatore, Albani, Wietse, Kuis, Marca H M, Wauben, Berent J, Prakken
Publikováno v:
Arthritis Research & Therapy
Juvenile idiopathic arthritis (JIA) is a heterogeneous autoimmune disease characterized by chronic joint inflammation. Knowing which antigens drive the autoreactive T-cell response in JIA is crucial for the understanding of disease pathogenesis and a
Autor:
William W. Kwok, Patrizia Marchese, Joellen Barnett, Amnon Altman, Berent J. Prakken, Francesca Giannoni, Rodrigo Samodal, Salvatore Albani, Eli E. Sercarz, Rosario Billetta, Mark R. Klein, Kun Bi, Paola Lanza, Randi Vita
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 174(6)
T cell activation is associated with active clustering of relevant molecules in membrane microdomains defined as the supramolecular activation cluster. The contact area between these regions on the surface of T cells and APC is defined as the immunol
Publikováno v:
Blood. 106:3238-3238
In the immunocompromised host adenovirus may cause fatal infections, especially after stem cell transplantation. No effective antiviral medication exists for severe adenoviral infection. Adoptively transferring adenoviral (Adv) specific T-cells from